Catalog No.
RHG34202
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20-1:50, WB: 1:1000-1:2000
Target
TNFR-associated protein 1, Heat shock protein 75 kDa, mitochondrial, HSP 75, Tumor necrosis factor type 1 receptor-associated protein, HSP75, TRAP-1, TRAP1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q12931
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D56
A prime-boost combination of a three-protein cocktail and multiepitopic MVA as a vaccine against Babesia bigemina elicits neutralizing antibodies and a Th1 cellular immune response in mice., PMID:35792436
Ruscogenin attenuated tight junction injury and tumor migration in colorectal liver metastasis mice via regulating TRAP1., PMID:35116472
TRAP1 Shows Clinical Significance in the Early Diagnosis of Small Cell Lung Cancer., PMID:34163209
Identification and characterization of a Babesia bigemina thrombospondin-related superfamily member, TRAP-1: a novel antigen containing neutralizing epitopes involved in merozoite invasion., PMID:33261638
TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas., PMID:33025742
TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening., PMID:32626957
Association of TRAP1 with infliximab-induced mucosal healing in Crohn's disease., PMID:31039275
Dnase1-deficient mice spontaneously develop a systemic lupus erythematosus-like disease., PMID:30758851
Identification and molecular characterization of a novel Babesia orientalis thrombospondin-related anonymous protein (BoTRAP1)., PMID:30587207
[Mechanism of protective effects of tumor necrosis factor receptor associated protein 1 on hypoxic cardiomyocytes of rats]., PMID:28043299
TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form., PMID:26065428
Impact of the tumor necrosis factor receptor-associated protein 1 (Trap1) on renal DNaseI shutdown and on progression of murine and human lupus nephritis., PMID:23273922
Impairment of oxidative stress-induced heme oxygenase-1 expression by the defect of Parkinson-related gene of PINK1., PMID:21366594
CD40/CD40L interaction induces E-selectin dependent leukocyte adhesion to human endothelial cells and inhibits endothelial cell migration., PMID:21138731
Antibody responses to galectin-8, TARP and TRAP1 in prostate cancer patients treated with a GM-CSF-secreting cellular immunotherapy., PMID:20499060
Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymphoma., PMID:20393185
Matrix metalloproteinase-10 is upregulated by thrombin in endothelial cells and increased in patients with enhanced thrombin generation., PMID:19762781
Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA)., PMID:17994629
Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network., PMID:17956728
Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium., PMID:17938804
A new role for FcgammaRIIA in the potentiation of human platelet activation induced by weak stimulation., PMID:16169188
A comprehensive study on the immunological reactivity of the Hsp90 molecular chaperone., PMID:15632312
Translocation of the Dictyostelium TRAP1 homologue to mitochondria induces a novel prestarvation response., PMID:15507488
Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the G(i)-independent activation of platelet Rap1B by thrombin., PMID:15078882
CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation., PMID:12676820
Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells., PMID:12379582
Unique behavior of a dictyostelium homologue of TRAP-1, coupling with differentiation of D. discoideum cells., PMID:12372338
Immunogold localization of mitochondrial aspartate aminotransferase in mitochondria and on the cell surface in normal rat tissues., PMID:11962739
Immunoelectron microscopy provides evidence that tumor necrosis factor receptor-associated protein 1 (TRAP-1) is a mitochondrial protein which also localizes at specific extramitochondrial sites., PMID:11010808
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties., PMID:10652318
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock., PMID:8756626
Ontogeny of CD40L [corrected] expression by activated peripheral blood lymphocytes in humans., PMID:8964605
For research use only. Not for human or drug use.
