Catalog No.
RHG29602
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
Fibulin-3, Fibrillin-like protein, EGF-containing fibulin-like extracellular matrix protein 1, FBNL, EFEMP1, FIBL-3, Extracellular protein S1-5, FBLN3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q12805
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D37
Inhibition of the extracellular matrix protein fibulin-3 reduces immunosuppressive signaling in tumor stem cells and increases macrophage activation against glioblastoma., PMID:39763756
The extracellular matrix protein fibulin-3/EFEMP1 promotes pleural mesothelioma growth by activation of PI3K/Akt signaling., PMID:36303838
Descriptive analysis of Fibulin-3 and the extracellular vesicle marker, Alix, in drusen from a small cohort of postmortem human eyes., PMID:33387484
Mesothelioma Biomarkers: Discovery in Search of Validation., PMID:33012429
The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice., PMID:31221853
Overexpressed fibulin-3 contributes to the pathogenesis of psoriasis by promoting angiogenesis., PMID:30146751
Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma., PMID:29146721
Interferon gamma-inducible protein 16 (IFI16) and anti-IFI16 antibodies in primary Sjögren's syndrome: findings in serum and minor salivary glands., PMID:26876186
Masquerade macular exudation in Mallatia Leventinese., PMID:26874169
Three cases of elastofibroma with immunohistochemical analysis of microfibrillar components., PMID:25672790
Comparison of drusen and modifying genes in autosomal dominant radial drusen and age-related macular degeneration., PMID:25077532
Responsiveness of choroidal neovascular membranes in patients with R345W mutation in fibulin 3 (Doyne honeycomb retinal dystrophy) to anti-vascular endothelial growth factor therapy., PMID:22159686
Identification of a preneoplastic gene expression profile in tubal epithelium of BRCA1 mutation carriers., PMID:21170264
Tropoelastin and fibulin overexpression in the subepithelial connective tissue of human pterygium., PMID:21094933
Proteome analysis of human aqueous humor., PMID:20463327
A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization., PMID:17324935
Aberrant accumulation of fibulin-3 in the endoplasmic reticulum leads to activation of the unfolded protein response and VEGF expression., PMID:16249470
Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells., PMID:16087305
Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family., PMID:14570714
Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration., PMID:12242346