Catalog No.
RHG14501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
CYP24A1, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450-CC24, 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, CYP24, Cytochrome P450 24A1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q07973
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D19
Differential Expression of Proteins Involved in Skin Barrier Maintenance and Vitamin D Metabolism in Atopic Dermatitis: A Cross-Sectional, Exploratory Study., PMID:39796069
Focusing on non-responders to infliximab with ulcerative colitis, what can we do first and next?, PMID:39191122
In ovo administration of the Marek's disease vaccine in conjunction with 25-hydroxyvitamin D3 and its subsequent effects on the performance and immunity-related characteristics of Ross 708 broiler hatchlings1,2,3., PMID:37939590
CYP24A1 Involvement in Inflammatory Factor Regulation Occurs via the Wnt Signaling Pathway., PMID:36255661
Plasma Protein Levels Analysis in Multiple Sclerosis Sardinian Families Identified C9 and CYP24A1 as Candidate Biomarkers., PMID:35207439
Vitamin D3 Treatment Alters Thyroid Functional Morphology in Orchidectomized Rat Model of Osteoporosis., PMID:35054977
Vitamin D-Related Genetics as Predictive Biomarker of Clinical Remission in Adalimumab-Treated Patients Affected by Crohn's Disease: A Pilot Study., PMID:34959633
Pollutants enhance IgE sensitization in the gut via local alteration of vitamin D-metabolizing enzymes., PMID:34504311
Impaired Vitamin D Signaling Is Associated With Frequent Development of Renal Cell Tumor in End-stage Kidney Disease., PMID:33109593
9-cis Retinoic acid and 1.25-dihydroxyvitamin D3 drive differentiation into IgA+ secreting plasmablasts in human naïve B cells., PMID:33107588
Association of increased renal Cyp24a1 gene expression with low plasma 1,25-dihydroxyvitamin D levels in rats with streptozotocin-induced diabetes., PMID:32001956
A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab., PMID:29208668
Diseases associated with calcium-sensing receptor., PMID:28122587
Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy., PMID:26238339
Comparable vitamin D3 metabolism in the endometrium of patients with recurrent spontaneous abortion and fertile controls., PMID:25914243
Anticancer activity of VDR-coregulator inhibitor PS121912., PMID:25107568
The vitamin D receptor (VDR) is expressed in skeletal muscle of male mice and modulates 25-hydroxyvitamin D (25OHD) uptake in myofibers., PMID:24949660
Vitamin D effects on B cell function in autoimmunity., PMID:24761763
Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice., PMID:24470103
Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease., PMID:23426901
Tumor-produced versican V1 enhances hCAP18/LL-37 expression in macrophages through activation of TLR2 and vitamin D3 signaling to promote ovarian cancer progression in vitro., PMID:23424670
Evidence for a genetic interaction in allergy-related responsiveness to vitamin D deficiency., PMID:22686937
Steroid requirements and immune associations with vitamin D are stronger in children than adults with asthma., PMID:22330698
Associations between genetic variants in vitamin D metabolism and asthma characteristics in young African Americans: a pilot study., PMID:21613960
The impact of chromatin organization of vitamin D target genes., PMID:16886674
Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway., PMID:16600026
Vitamin D(3) metabolism in human glioblastoma multiforme: functionality of CYP27B1 splice variants, metabolism of calcidiol, and effect of calcitriol., PMID:16061850
Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3., PMID:15919092
Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter., PMID:15863722
Using chromatin immunoprecipitation to monitor 1alpha,25-dihydroxyvitamin D3-dependent chromatin activity on the human CYP24 promoter., PMID:15225785
Calcitonin stimulates expression of the rat 25-hydroxyvitamin D3-24-hydroxylase (CYP24) promoter in HEK-293 cells expressing calcitonin receptor: identification of signaling pathways., PMID:14765994
Isoflavonoids inhibit catabolism of vitamin D in prostate cancer cells., PMID:12270218
1alpha,25-(OH)2D3 regulates 25-hydroxyvitamin D3 24R-hydroxylase activity in growth zone costochondral growth plate chondrocytes via protein kinase C., PMID:11800234
Vitamin D and prostate cancer., PMID:11384870
Differential regulation of direct repeat 3 vitamin D3 and direct repeat 4 thyroid hormone signaling pathways by the human TR4 orphan receptor., PMID:10347174
Differential regulation of gene transcription in subpopulations of human B lymphocytes by vitamin D3., PMID:9886849
Additional protein factors play a role in the formation of VDR/RXR complexes on vitamin D response elements., PMID:9827697
Anchorage-dependent expression of the vitamin D receptor in normal human keratinocytes., PMID:9764832
A highly sensitive method for large-scale measurements of 1,25-dihydroxyvitamin D., PMID:9448854
Retinoid X receptor-specific ligands synergistically upregulate 1, 25-dihydroxyvitamin D3-dependent transcription in epidermal keratinocytes in vitro and in vivo., PMID:9077482
Assay of 1,25-dihydroxyvitamin D3 from serum samples: use of receptor-binding or enzyme-coupled reporter analysis., PMID:9330286
Cloning of the human 1 alpha,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements., PMID:7632726
Identification of the porcine intestinal accessory factor that enables DNA sequence recognition by vitamin D receptor., PMID:7708726
Quantitative immunoelectron microscopic analysis of the localization and induction of 25-hydroxyvitamin D3 24-hydroxylase in rat kidney., PMID:7868855
The vitamin D3 hydroxylase-associated protein is a propionamide-metabolizing amidase enzyme., PMID:7840608
Further oxidation of hydroxycalcidiol by calcidiol 24-hydroxylase. A study with the mature enzyme expressed in Escherichia coli., PMID:7925346
Immunolocalization of calcitriol receptor, 24-hydroxylase cytochrome P-450, and calbindin D28k in human kidney., PMID:8160797
cDNA cloning and characterization of a vitamin D3 hydroxylase-associated protein., PMID:8276793
Separation of two forms of chick 1,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 24-hydroxylase., PMID:8115349
Immunopurified 25-hydroxyvitamin D 1 alpha-hydroxylase and 1,25-dihydroxyvitamin D 24-hydroxylase are closely related but distinct enzymes., PMID:1310688
For research use only. Not for human or drug use.
