Anti-TFF3 Antibody (R2D07)

Catalog No.

RHG12801

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

Polypeptide P1.B, Trefoil factor 3, TFF3, hITF, ITF, Intestinal trefoil factor, TFI, hP1.B

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q07654

Applications

FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2D07

Protective effect of Dulaglutide, a GLP1 agonist, on acetic acid-induced ulcerative colitis in rats: involvement of GLP-1, TFF-3, and TGF-β/PI3K/NF-κB signaling pathway., PMID:39579211

Protective Effect of IgY Embedded in W/O/W Emulsion on LPS Enteritis-Induced Colonic Injury in Mice., PMID:39408328

Different Forms of TFF3 in the Human Endocervix, including a Complex with IgG Fc Binding Protein (FCGBP), and Further Aspects of the Cervico-Vaginal Innate Immune Barrier., PMID:38396964

Intestinal injury and vasculitis biomarkers in cats with feline enteric coronavirus and effusive feline infectious peritonitis., PMID:37872840

Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole-slide imaging and accurate segmentation., PMID:37741277

Different Molecular Forms of TFF3 in the Human Respiratory Tract: Heterodimerization with IgG Fc Binding Protein (FCGBP) and Proteolytic Cleavage in Bronchial Secretions., PMID:36499686

Deciphering the Immune Complexity in Esophageal Adenocarcinoma and Pre-Cancerous Lesions With Sequential Multiplex Immunohistochemistry and Sparse Subspace Clustering Approach., PMID:35663986

The Association of Trefoil Factors with Gastric Cancer and Premalignant Lesions: A Cross-Sectional Population-Based Cohort Study., PMID:35027436

HOXB13 and TFF3 can contribute to the prognostic stratification of prostate adenocarcinoma., PMID:34609407

Structural and quantitative alterations of gut microbiota in experimental small bowel obstruction., PMID:34347831

CD147 receptor is essential for TFF3-mediated signaling regulating colorectal cancer progression., PMID:34262017

Expression of trefoil factor 3 is decreased in colorectal cancer., PMID:33210724

Gene Expression Analysis by Real-Time PCR in Nasal Brushings of Adult Patients with Allergic Rhinitis, Suspected Allergic Rhinitis, and Nonallergic Rhinitis., PMID:33171477

Cytokine Profiling in Chinese SLE Patients: Correlations with Renal Dysfunction., PMID:33134397

Dietary Soy Protein Isolate Attenuates Intestinal Immunoglobulin and Mucin Expression in Young Mice Compared with Casein., PMID:32911830

Trefoil factor(s) and CA19.9: A promising panel for early detection of pancreatic cancer., PMID:30956167

Production of Monoclonal Antibodies against Human Trefoil Factor 3 and Development of a Modified-Sandwich ELISA for Detection of Trefoil Factor 3 Homodimer in Saliva., PMID:29151819

Hypomethylation associated enhanced transcription of trefoil factor-3 mediates tamoxifen-stimulated oncogenicity of ER+ endometrial carcinoma cells., PMID:29100386

MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance., PMID:29099279

Obstructive sleep apnea and rhonchopathy are associated with downregulation of trefoil factor family peptide 3 (TFF3)-Implications of changes in oral mucus composition., PMID:29028798

Localization of trefoil factor family peptide 3 (TFF3) in epithelial tissues originating from the three germ layers of developing mouse embryo., PMID:28485250

Trefoil factor-3 is not a useful marker of mucosal healing in Crohn's disease treated with anti-TNF-α antibodies., PMID:28104989

Trefoil Factor-3 (TFF3) Stimulates De Novo Angiogenesis in Mammary Carcinoma both Directly and Indirectly via IL-8/CXCR2., PMID:26559818

Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation., PMID:26307678

Heterogeneous Nuclear Ribonucleoprotein A1 Improves the Intestinal Injury by Regulating Apoptosis Through Trefoil Factor 2 in Mice with Anti-CD3-induced Enteritis., PMID:25901972

TFF3 is a valuable predictive biomarker of endocrine response in metastatic breast cancer., PMID:25900183

Dietary intervention with serum-derived bovine immunoglobulins protects barrier function in a mouse model of colitis., PMID:25882614

Proteomics urine analysis of pregnant women suffering from multiple sclerosis., PMID:25793971

Trefoil factor family peptides TFF1 and TFF3 in the nervous tissues of developing mouse embryo., PMID:25725142

mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer., PMID:25710561

Carbonic anhydrase 4 and crystallin α-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology., PMID:24880201

Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China., PMID:24720760

Inhibition of ErbB-2 induces TFF3 downregulation in breast cancer cell lines., PMID:24164280

Mucosal barrier in ulcerative colitis and Crohn's disease., PMID:23737764

A variant form of the human deleted in malignant brain tumor 1 (DMBT1) gene shows increased expression in inflammatory bowel diseases and interacts with dimeric trefoil factor 3 (TFF3)., PMID:23691218

Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns., PMID:23660296

Trefoil factor family 3 (TFF3) expression and its interaction with estrogen receptor (ER) in endometrial adenocarcinoma., PMID:23578537

Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice., PMID:23178499

Influence of Helicobacter pylori status and eradication on the serum levels of trefoil factors and pepsinogen test: serum trefoil factor 3 is a stable biomarker., PMID:22907485

Trefoil factor family protein 3 (TFF3) is present in cartilage during endochondral ossification in the developing mouse fetus., PMID:22818426

TFF3 is a normal breast epithelial protein and is associated with differentiated phenotype in early breast cancer but predisposes to invasion and metastasis in advanced disease., PMID:22341453

The rat IgGFcγBP and Muc2 C-terminal domains and TFF3 in two intestinal mucus layers bind together by covalent interaction., PMID:21629776

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk., PMID:21455714

Trefoil factor family peptides in human saliva and cyclical cervical mucus. Method evaluation and results on healthy individuals., PMID:21275809

A chimeric peptide of intestinal trefoil factor containing cholesteryl ester transfer protein B cell epitope significantly inhibits atherosclerosis in rabbits after oral administration., PMID:21192999

Trefoil factor 3 is oncogenic and mediates anti-estrogen resistance in human mammary carcinoma., PMID:21170268

Pseudopod-like basal cell processes in intestinal cholecystokinin cells., PMID:20582553

Butyrate enemas do not affect human colonic MUC2 and TFF3 expression., PMID:20461009

[Expression of human TFF3 in Escherichia coli]., PMID:20369483

Trefoil factor family 3 expression in the oral cavity., PMID:20121925

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