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Anti-PSME1 Antibody (R2C83)

Catalog #:   RHG08501 Specific References (31) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IP, WB
Accession: Q06323
Overview

Catalog No.

RHG08501

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

11S regulator complex subunit alpha, Proteasome activator complex subunit 1, Proteasome activator 28 subunit alpha, IGUP I-5111, Interferon gamma up-regulated I-5111 protein, PA28a, Activator of multicatalytic protease subunit 1, PSME1, IFI5111, REG-alpha, PA28alpha

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q06323

Applications

IF, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2C83

Data Image
  • Western blot
    Western blot analysis of PSME1 expression in Jurkat cell lysate.
References

Obesity enhances the response to neoadjuvant anti-PD1 therapy in oral tongue squamous cell carcinoma., PMID:38923758

iTRAQ-based proteomic analysis of differentially expressed proteins in sera of seronegative and seropositive rheumatoid arthritis patients., PMID:34812532

Downregulation of PA28α induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma., PMID:33318477

Proteomics show antigen presentation processes in human immune cells after AS03-H5N1 vaccination., PMID:28508465

Antibody-validated proteins in inflamed islets of fulminant type 1 diabetes profiled by laser-capture microdissection followed by mass spectrometry., PMID:25329145

Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy., PMID:25226551

Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies., PMID:23918357

Molecular and functional characterization of a putative PA28γ proteasome activator orthologue in Schistosoma mansoni., PMID:23611749

The C-terminal fragment of the immunoproteasome PA28S (Reg alpha) as an early diagnosis and tumor-relapse biomarker: evidence from mass spectrometry profiling., PMID:22532226

Using proteomic approach to identify tumor-associated proteins as biomarkers in human esophageal squamous cell carcinoma., PMID:21517111

The immunoproteasome in steatohepatitis: its role in Mallory-Denk body formation., PMID:21256843

Enhancement of proteasome function by PA28α overexpression protects against oxidative stress., PMID:21098724

Anti-proteasome activator 28alpha is a novel anti-cytoplasmic antibody in patients with systemic lupus erythematosus and Sjögren's syndrome., PMID:19688289

Specific MALDI imaging and profiling for biomarker hunting and validation: fragment of the 11S proteasome activator complex, Reg alpha fragment, is a new potential ovary cancer biomarker., PMID:17939699

Comparative proteomics analysis to annexin B1 DNA and protein vaccination in mice., PMID:17027125

Anti-20S proteasome autoantibodies inhibit proteasome stimulation by proteasome activator PA28., PMID:16802355

The ubiquitin-proteasome system plays essential roles in presenting an 8-mer CTL epitope expressed in APC to corresponding CD8+ T cells., PMID:16569681

Proteasomes and antigen presentation: evidence that a KEKE motif does not promote presentation of the class I epitope SIINFEKL., PMID:16423396

Antigen presentation and immune regulatory capacity of immature and mature-enriched antigen presenting (dendritic) cells derived from human bone marrow., PMID:14969764

Autoimmune response to proteasome activator 28alpha in patients with connective tissue diseases., PMID:14760793

Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells., PMID:12407112

Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation., PMID:11717192

Interferon gamma regulates accumulation of the proteasome activator PA28 and immunoproteasomes at nuclear PML bodies., PMID:11112687

Tissue distribution of constitutive proteasomes, immunoproteasomes, and PA28 in rats., PMID:11032729

The proteasome activator 11 S REG (PA28) and class I antigen presentation., PMID:10600633

Proteasome activator subunit PA28 alpha and related Ki antigen (PA28 gamma) are absent from the nuclear fraction purified by sucrose gradient centrifugation., PMID:10216960

Conformational changes in the 20S proteasome upon macromolecular ligand binding analyzed with monoclonal antibodies., PMID:9989942

Invasion by Salmonella typhimurium induces increased expression of the LMP, MECL, and PA28 proteasome genes and changes in the peptide repertoire of HLA-B27., PMID:9746558

Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes., PMID:9620878

Molecular properties of the proteasome activator PA28 family proteins and gamma-interferon regulation., PMID:9189757

Phosphorylation of the proteasome activator PA28 is required for proteasome activation., PMID:8780702

Datasheet

Document Download

Anti-PSME1 Antibody (R2C83).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-PSME1 Antibody (R2C83) [RHG08501]
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