Catalog No.
RHG05503
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Sphingosine-dependent protein kinase-1, PRKCD, Protein kinase C delta type, PKCD, nPKC-delta, Tyrosine-protein kinase PRKCD, SDK1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q05655, Q04759, P28867
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2C68
Neuroprotective effects of Elaeagnus glabra f. oxyphylla extract in amyloid-beta-induced cognitive deficit mice: Involvement of the PKC-delta, MYL2, and FER pathways., PMID:39532004
TLR Engagement Induces an Alternate Pathway for BCR Signaling that Results in PKCδ Phosphorylation., PMID:38629913
Role of Arctiin in Fibrosis and Apoptosis in Experimentally Induced Hepatocellular Carcinoma in Rats., PMID:38205087
Effects of Simvastatin on RBL-2H3 Cell Degranulation., PMID:37394638
Extracellular Release of Citrullinated Vimentin Directly Acts on Osteoclasts to Promote Bone Resorption in a Mouse Model of Periodontitis., PMID:37190018
Signal responses to neutral TSH receptor antibody - A cycle of damage in the pathophysiology of Graves' disease., PMID:36898184
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics., PMID:36503013
Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria., PMID:34693907
TREM (Triggering Receptor Expressed on Myeloid Cells)-1 Inhibition Attenuates Neuroinflammation via PKC (Protein Kinase C) δ/CARD9 (Caspase Recruitment Domain Family Member 9) Signaling Pathway After Intracerebral Hemorrhage in Mice., PMID:33947214
Unconventional Secretion of PKCδ Exerts Tumorigenic Function via Stimulation of ERK1/2 Signaling in Liver Cancer., PMID:33318039
Actin reorganization at the centrosomal area and the immune synapse regulates polarized secretory traffic of multivesicular bodies in T lymphocytes., PMID:32939232
The Laminin-Induced Phosphorylation of PKCδ Regulates AQP4 Distribution and Water Permeability in Rat Astrocytes., PMID:32851539
Obligatory role for PKCδ in PIP2 -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cells., PMID:32627185
Protein Kinase C δ (PKCδ) Attenuates Bleomycin Induced Pulmonary Fibrosis via Inhibiting NF-κB Signaling Pathway., PMID:32390869
Activation of Protein Kinase Cδ Contributes to the Induction of Src/EGF Receptor/ERK Signaling in Ammonia-treated Astrocytes., PMID:32125625
Suppression of β1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats., PMID:31947691
Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ., PMID:31330227
Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cells., PMID:31239481
Identification and characterisation of lamprey protein kinase C delta-like gene., PMID:28939820
PKC-δ attenuates the cancer stem cell among squamous cell carcinoma cells through down-regulating p63., PMID:28756980
Requirement of Gαq/Gα11 Signaling in the Preservation of Mouse Intestinal Epithelial Homeostasis., PMID:28174748
Distinctive and selective route of PI3K/PKCα-PKCδ/RhoA-Rac1 signaling in osteoclastic cell migration., PMID:27576187
Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin., PMID:27203386
Design of a PKCδ-specific small peptide as a theragnostic agent for glioblastoma., PMID:26739937
Inhibitory effect of fermented Arctium lappa fruit extract on the IgE-mediated allergic response in RBL‑2H3 cells., PMID:26707911
Overcoming rituximab drug-resistance by the genetically engineered anti-CD20-hIFN-α fusion protein: Direct cytotoxicity and synergy with chemotherapy., PMID:26398317
'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma, anti-GluR-delta2, anti-Ca/ARHGAP26 and anti-VGCC., PMID:26377184
Melatonin-mediated inhibition of Purkinje neuron P-type Ca²⁺ channels in vitro induces neuronal hyperexcitability through the phosphatidylinositol 3-kinase-dependent protein kinase C delta pathway., PMID:25707622
Bacterial flagellin induces IL-6 expression in human basophils., PMID:25660969
Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: involvement of protein kinase C-θ activation., PMID:25638159
CDCP1 identifies a CD146 negative subset of marrow fibroblasts involved with cytokine production., PMID:25275584
PKCδ/midkine pathway drives hypoxia-induced proliferation and differentiation of human lung epithelial cells., PMID:24500281
Apigenin in combination with Akt inhibition significantly enhances thyrotropin-stimulated radioiodide accumulation in thyroid cells., PMID:24400871
Inhibitory effects of mulberry fruit extract in combination with naringinase on the allergic response in IgE-activated RBL-2H3 cells., PMID:24336971
Ligand- and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists., PMID:24022593
Protein kinase C-δ-mediated recycling of active KIT in colon cancer., PMID:23881925
PKC-ε pseudosubstrate and catalytic activity are necessary for membrane delivery during IgG-mediated phagocytosis., PMID:23670290
Epigenetic dysregulation in salivary glands from patients with primary Sjögren's syndrome may be ascribed to infiltrating B cells., PMID:23478041
Parathyroid hormone (1-34) counteracts the suppression of interleukin-11 expression by glucocorticoid in murine osteoblasts: a possible mechanism for stimulating osteoblast differentiation against glucocorticoid excess., PMID:23397032
Expression pattern of protein kinase Cδ during mouse embryogenesis., PMID:23305608
Glycoxidised LDL induced the upregulation of Axl receptor tyrosine kinase and its ligand in mouse mesangial cells., PMID:23226259
Carbon tetrachloride-induced hepatic injury through formation of oxidized diacylglycerol and activation of the PKC/NF-κB pathway., PMID:23207450
Protein kinase Cβ is critical for the metabolic switch to glycolysis following B-cell antigen receptor engagement., PMID:22994860
Analysis of substrates of protein kinase C isoforms in human breast cells by the traceable kinase method., PMID:22897107
Polymeric black tea polyphenols modulate the localization and activity of 12-O-tetradecanoylphorbol-13-acetate-mediated kinases in mouse skin: mechanisms of their anti-tumor-promoting action., PMID:22841871
Neuromedin S increases L-type Ca(2+) channel currents through G(i)α-protein and phospholipase C-dependent novel protein kinase C delta pathway in adult rat ventricular myocytes., PMID:22832358
Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling., PMID:22761689
PKC activation is required for TSH-mediated lipolysis via perilipin activation., PMID:22730012
Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2., PMID:22544939
Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation., PMID:22540228
For research use only. Not for human or drug use.
