Catalog No.
YHC84401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp11-Glu276
Predicted molecular weight
32.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10914
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interferon regulatory factor 1, IRF-1, IRF1
Identification of genes associated with liver ischemia-reperfusion injury after liver transplantation by WGCNA and PPI network analyses., PMID:40505700
Expression of Immune-Related Genes and Possible Regulatory Mechanisms in Chronic Antibody-Mediated Rejection after Kidney Transplantation., PMID:40495508
Transcriptional characterization of sepsis in a LPS porcine model., PMID:40471388
The AhR regulates IFN-induced immune checkpoints in lung cancer cells through HNRNPH1, an RNA-binding protein, and INCR1, a novel long non-coding RNA., PMID:40449595
Elucidating the chromatin-driven transcription regulatory networks response to Streptococcus agalactiae infection under low temperature in Nile tilapia., PMID:40441668
Interferon regulatory factor-1-expressing astrocytes are epigenetically controlled and exacerbate TBI-associated pathology in mice., PMID:40435213
Mapping Inherited Genetic Variation with Opposite Effects on Autoimmune Disease and Four Cancer Types Identifies Candidate Drug Targets Associated with the Anti-Tumor Immune Response., PMID:40428397
Uncovering dendritic cell specific biomarkers for diagnosis and prognosis of cardiomyopathy using single cell RNA sequencing and comprehensive bioinformatics analysis., PMID:40419517
Single cell RNA-sequencing identified CCR7+/RELB+/IRF1+ T cell responding for juvenile idiopathic arthritis pathogenesis., PMID:40406113
Regulation of Immune-Related Gene Expression by Salinity-Induced HPI Axis in Large Yellow Croaker, Larimichthys crocea., PMID:40362534
The role of DDIT3 in modulating proliferation and tamoxifen resistance in luminal A subtype breast cancer through the DDIT3-IRF1 axis., PMID:40359764
Licochalcone B attenuates pulmonary fibrosis via inhibiting ZBP1-dependent PANoptosis., PMID:40350052
Fludarabine attenuates inflammation and dysregulated autophagy in alveolar macrophages via inhibition of STAT1/IRF1 pathway., PMID:40336064
Reprograming Model of Human Monocyte-derived Macrophages for In-vitro Assays., PMID:40323795
Identification of PANoptosis related biomarkers to predict hepatic ischemia‒reperfusion injury after liver transplantation., PMID:40316717
Functional Attributes of Synovial Fluid from Osteoarthritic Knee Exacerbate Cellular Inflammation and Metabolic Stress, and Fosters Monocyte to Macrophage Differentiation., PMID:40299511
13C and 15N resonance assignments of the DNA binding domain of interferon regulatory factor-3., PMID:40293680
IL-10 targets IRF transcription factors to suppress IFN and inflammatory response genes by epigenetic mechanisms., PMID:40263613
Reversible downregulation of HLA class I in adenoid cystic carcinoma., PMID:40254393
Epigenomic regulation of stemness contributes to the low immunogenicity of the most mutated human cancer., PMID:40250424
Interferon Regulatory Factors as a Potential Therapeutic Target for Neuroinflammation: A Focus on Alzheimer's Disease., PMID:40243463
Down-Regulation of HLA-C Expression on Melanocytes May Contribute to the Therapeutic Efficacy of UVB Phototherapy in Psoriasis., PMID:40243413
Association of interferon regulator factor 1 upregulation with pulmonary arterial hypertension., PMID:40223959
Vascular smooth muscle cell-derived SO2 sulphenylated interferon regulatory factor 1 to inhibit VSMC senescence., PMID:40223932
A bovine pulmosphere model and multiomics reveal early host response signature in tuberculosis., PMID:40186000
The critical role of the ZBP1-NINJ1 axis and IRF1/IRF9 in ethanol-induced cell death, PANoptosis, and alcohol-associated liver disease., PMID:40161842
α-Hederin causes ferroptosis in triple-negative breast cancer through modulating IRF1 to suppress GPX4., PMID:40153970
Interferon regulatory factor 1 contributes to metabolic dysfunction associated steatotic liver disease., PMID:40132726
PARP7 as a new target for activating anti-tumor immunity in cancer., PMID:40128585
Unveiling the Hub Genes Associated with the Enhanced Effects of Selenium on Pancreas Function in Diabetic Mice., PMID:40128492
Aregs-IGFBP3-mediated SMC-like cells apoptosis impairs beige adipocytes formation in aged mice., PMID:40118146
LncRNA EMBP1 sponges miR-454-3p to upregulate IRF1 and activate NLRP3-mediated chondrocyte pyroptosis to drive osteoarthritis progression., PMID:40112602
Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia., PMID:40106574
IRF1 regulates autophagy and microglia polarization in retinal ischemia-reperfusion through NCOA1/Wnt/β-catenin signalling pathway., PMID:40096931
Bioinformatics identification and validation of pyroptosis-related gene for ischemic stroke., PMID:40091022
Interferon Regulatory Factor 1 Promotes Diabetic Vasculopathy by Mediating Endothelial Cell Pyroptosis., PMID:40086624
Loss of ARID1A leads to a cold tumor phenotype via suppression of IFNγ signaling., PMID:40082458
Analysis of the Transcriptional Control of Bcl11b in Chicken: IRF1 and GATA1 as Negative Regulators., PMID:40075948
A novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics., PMID:40072380
BATF2 is a regulator of interferon-γ signaling in astrocytes during neuroinflammation., PMID:40057949
Identification of a type I IFN- and IRF-inducible enhancer in the 5'-UTR intron of MAVS in large yellow croaker Larimichthys crocea., PMID:40020953
Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn's disease., PMID:40018047
Administration of a Recombinant Fusion Protein of IFN-γ and CD154 Inhibited the Infection of Chicks with Salmonella enterica., PMID:40005871
The Effects of Fisetin on Gene Expression Profile and Cellular Metabolism in IFN-γ-Stimulated Macrophage Inflammation., PMID:40002369
Identification of crucial genes for polycystic ovary syndrome and atherosclerosis through comprehensive bioinformatics analysis and machine learning., PMID:39981695
The MLL3/GRHL2 complex regulates malignant transformation and anti-tumor immunity in squamous cancer., PMID:39964485
Identification of benzo(a)pyrene-related toxicological targets and their role in chronic obstructive pulmonary disease pathogenesis: a comprehensive bioinformatics and machine learning approach., PMID:39962573
GAMG alleviates liver fibrosis through inducing ferroptosis in inflammatory macrophages via the IRF1/SLC7A11 signaling pathway., PMID:39904190
IRF1-RIG-I signaling defects in the aged alveolar epithelial cells may contribute to decreased pulmonary antiviral immune responses., PMID:39874992
ZBP1 senses Brucella abortus DNA triggering type I interferon signaling pathway and unfolded protein response activation., PMID:39850894
For research use only. Not for human or drug use.
