Catalog No.
YHC84001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp239-Glu457
Predicted molecular weight
27.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10828
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ERBA2, Nuclear receptor subfamily 1 group A member 2, c-erbA-beta, THRB, c-erbA-2, Thyroid hormone receptor beta, THR1, NR1A2
Loss of adult visual responses by developmental BPA exposure is correlated with altered estrogenic signaling., PMID:40456881
Disease-associated SNP variants of THRβ: Insights into the molecular determinants of aberrant receptor function., PMID:40419015
Canagliflozin alleviates progestin resistance by suppressing RARβ/CRABP2 signaling in THRB knockout endometrial cancer cells., PMID:40371351
Identification of new families and variants in autosomal dominant macular dystrophy associated with THRB., PMID:40295579
Multiomic insight into the involvement of cell aging related genes in the pathogenesis of endometriosis., PMID:40269081
Avian photoreceptor homologies and the origin of double cones., PMID:40250431
A high-fructose diet leads to osteoporosis by suppressing the expression of Thrb and facilitating the accumulation of cholesterol., PMID:40204733
Exploration of non-coding RNAs related to intramuscular fat deposition Xinjiang Brown cattle and Angus × Wagyu cattle., PMID:40087563
Thyroid hormone signaling is essential for the maturation and survival of cochlear root cells in mice., PMID:40024091
Exposure to bisphenol A and sodium nitrate found in processed meat induces endocrine disruption and dyslipidemia through PI3K/AKT/SREBP pathway in zebrafish larvae., PMID:40023200
Audiological alterations in resistance to thyroid hormone syndrome: emphasizing lifelong assessment., PMID:39945573
A preliminary report to discern the association of SNPs rs1505287 and rs4858608 of THRB gene and their haplotype analysis with hypothyroidism and hyperthyroidism among Indian population: A case-control study., PMID:39921048
Comparative analysis of chromatin accessibility in porcine oocytes from follicles of different sizes., PMID:39908890
Clinical Characteristics and Genotype-phenotype Correlation in Turkish Patients with a Diagnosis of Resistance to Thyroid Hormone Beta., PMID:39713907
Ontogeny of Thyroid Hormone Signaling in the Retina of Zebrafish: Effects of Thyroidal Status on Retinal Morphology, Cell Survival, and Color Preference., PMID:39596289
Structural Insights Into Thyroid Hormone Receptors., PMID:39541421
The effect of diet-induced weight-loss on subcutaneous adipose tissue expression of genes associated with thyroid hormone action., PMID:39527910
Thyroid hormone receptor beta (THRβ1) is the major regulator of T3 action in human iPSC-derived hepatocytes., PMID:39481850
The Clinical and Genetic Diversity of Thyroid Hormone Resistance: Four Clinical Vignettes., PMID:39476806
Valencene as a novel potential downregulator of THRB in NSCLC: network pharmacology, molecular docking, molecular dynamics simulation, ADMET analysis, and in vitro analysis., PMID:39425858
Actions of thyroid hormones and thyromimetics on the liver., PMID:39420154
Increased cardiovascular morbidity and reduced life expectancy in a large Italian cohort of patients with resistance to thyroid hormone β (RTHβ)., PMID:39327977
Epigenetic regulation of thyroid hormone action in human metabolic dysfunction-associated steatohepatitis., PMID:39312733
Effects of L-NAME and air exposure on mitochondrial energetic markers, thyroid hormone receptor/regulator system and stress/ease-responsive receptor expression in the brain/gut axis of zebrafish., PMID:39306267
ToxDAR: A Workflow Software for Analyzing Toxicologically Relevant Proteomic and Transcriptomic Data, from Data Preparation to Toxicological Mechanism Elucidation., PMID:39273492
Cone photoreceptor differentiation regulated by thyroid hormone transporter MCT8 in the retinal pigment epithelium., PMID:39018199
Assessment of Cardiometabolic Risk Factors and Insulin Sensitivity by Hyperinsulinemic-Euglycemic Clamp in Resistance to Thyroid Hormone β Syndrome., PMID:38877800
Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression., PMID:38718793
Transcriptomic profiling of Rana [Lithobates] catesbeiana back skin during natural and thyroid hormone-induced metamorphosis under different temperature regimes with particular emphasis on innate immune system components., PMID:38714098
Nr1h4 and Thrb ameliorate ER stress and provide protection in the MPTP mouse model of Parkinson's., PMID:38609183
Identification of relevant differential genes to the divergent development of pectoral muscle in ducks by transcriptomic analysis., PMID:38575126
A rare mutation in THRB gene of resistance to thyroid hormone: a case report of a Chinese pedigree., PMID:38547395
The dynamic landscape of chromatin accessibility and active regulatory elements in the mediobasal hypothalamus influences the seasonal activation of the reproductive axis in the male quail under long light exposure., PMID:38373887
Molecular mechanisms of hypothalamic-pituitary-ovarian/thyroid axis regulating age at first egg in geese., PMID:38295497
Generation of THRB-GS(E125G_G126S) and THRB-KO human iPSC lines to study noncanonical thyroid hormone signalling., PMID:38100912
Thyroid hormone-regulated chromatin landscape and transcriptional sensitivity of the pituitary gland., PMID:38081939
Thyroid hormone receptor Thra and Thrb knockout differentially affects osteoblast biology and thyroid hormone responsiveness in vitro., PMID:37992217
Functional enrichment analysis of mutated genes in children with hyperthyroidism., PMID:37876543
Mapping temperature-sensitive mutations at a genome scale to engineer growth switches in Escherichia coli., PMID:37642940
The Relationship Between Fetal THRB Genotype and Maternal Thyroid Function., PMID:37597194
A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action., PMID:37594753
Expanding the phenotype of THRB: a range of macular dystrophies as the major clinical manifestations in patients with a dominant splicing variant., PMID:37547476
An extended transcription factor regulatory network controls hepatocyte identity., PMID:37424431
Thyroid hormone regulates proximodistal patterning in fin rays., PMID:37186843
Regulation of Thyroid Hormone Levels by Hypothalamic Thyrotropin-Releasing Hormone Neurons., PMID:37166378
Effect of the Fetal THRB Genotype on the Placenta., PMID:37149816
Thyroid hormone resistance resulting from a novel mutation in the THRB gene in a Chinese child: A case report., PMID:37115071
Biphasic expression of thyroid hormone receptor TRβ1 in mammalian retina and anterior ocular tissues., PMID:37033230
Reactivated thyroid hormone receptor β attenuates anaplastic thyroid cancer (ATC) stem cell activity., PMID:36939877
Single-cell profiling reveals Müller glia coordinate retinal intercellular communication during light/dark adaptation via thyroid hormone signaling., PMID:36930538
For research use only. Not for human or drug use.
