Catalog No.
YHC83901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro490
Predicted molecular weight
57.12 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10827
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NR1A1, EAR7, c-erbA-alpha, Thyroid hormone receptor alpha, EAR-7, THRA, c-erbA-1, Nuclear receptor subfamily 1 group A member 1, ERBA1, THRA2, V-erbA-related protein 7, THRA1
Visceral adipocyte metabolic dysfunction in obesity related to altered chromatin accessibility to thyroid hormone receptor., PMID:40367997
Generation of hiPSC lines with fusion tagged thyroid hormone receptor α isoforms to study isoform-specific actions of TRα1 and TRα2., PMID:40286604
Thyroid hormone signaling is essential for the maturation and survival of cochlear root cells in mice., PMID:40024091
TRα1 mutant suppresses KLF9 to cause endometrial metaplasia with ectopic IL-33 expression leading to uterine fibrosis and infertility., PMID:39890871
Bichromatic Splicing Detector Allows Quantification of THRA1 and THRA2 Splicing Isoforms in Single Cells by Fluorescent Live-Cell Imaging., PMID:39769274
Metabolic Engineering of Escherichia coli for Efficient Production of Ectoine., PMID:39723826
Structural Insights Into Thyroid Hormone Receptors., PMID:39541421
The effect of diet-induced weight-loss on subcutaneous adipose tissue expression of genes associated with thyroid hormone action., PMID:39527910
The Clinical and Genetic Diversity of Thyroid Hormone Resistance: Four Clinical Vignettes., PMID:39476806
Actions of thyroid hormones and thyromimetics on the liver., PMID:39420154
RNA Sequencing Reveals a Strong Predominance of THRA Splicing Isoform 2 in the Developing and Adult Human Brain., PMID:39337374
Epigenetic regulation of thyroid hormone action in human metabolic dysfunction-associated steatohepatitis., PMID:39312733
Effects of L-NAME and air exposure on mitochondrial energetic markers, thyroid hormone receptor/regulator system and stress/ease-responsive receptor expression in the brain/gut axis of zebrafish., PMID:39306267
Normal Values for the fT3/fT4 Ratio: Centile Charts (0-29 Years) and Their Application for the Differential Diagnosis of Children with Developmental Delay., PMID:39201272
Unraveling the molecular pathogenesis of Type 2 Diabetes and its impact on female infertility: A bioinformatics and systems biology approach., PMID:39116715
Fine and combinatorial regulation of key metabolic pathway for enhanced β-alanine biosynthesis with non-inducible Escherichia coli., PMID:38978393
Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization., PMID:38867170
Combined transcriptome and metabolome analyses reveal the effects of selenium on the growth and quality of Lilium lancifolium., PMID:38828223
Effectiveness and safety of PD-1/PD-L1 inhibitors monotherapy in patients with endometrial cancer., PMID:38750182
Spatiotemporal expression of thyroid hormone transporter MCT8 and THRA mRNA in human cerebral organoids recapitulating first trimester cortex development., PMID:38654093
The dynamic landscape of chromatin accessibility and active regulatory elements in the mediobasal hypothalamus influences the seasonal activation of the reproductive axis in the male quail under long light exposure., PMID:38373887
Overlaps Between CDS Regions of Protein-Coding Genes in the Human Genome: A Case Study on the NR1D1-THRA Gene Pair., PMID:38006429
Thyroid hormone receptor Thra and Thrb knockout differentially affects osteoblast biology and thyroid hormone responsiveness in vitro., PMID:37992217
Thyroid hormone receptor α1: a novel regulator of thyroid cancer cell differentiation., PMID:37634007
A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action., PMID:37594753
Genome-wide analysis of sex-specific differences in the mother-child PELAGIE cohort exposed to organophosphate metabolites., PMID:37198424
Effect of the Fetal THRB Genotype on the Placenta., PMID:37149816
The Genetic Landscape of Children Born Small for Gestational Age with Persistent Short Stature., PMID:37019085
AflQ1-Q2 represses lincomycin biosynthesis via multiple cascades in Streptomyces lincolnensis., PMID:36930277
Relationship between serum thyroid hormones and their associated metabolites, and gene expression bioindicators in the back skin of Rana [Lithobates] catesbeiana tadpoles and frogs during metamorphosis., PMID:36743912
Organ-specific effects on target binding due to knockout of thyroid hormone receptor α during Xenopus metamorphosis., PMID:36397722
CycA-Dependent Glycine Assimilation Is Connected to Novobiocin Susceptibility in Escherichia coli., PMID:36377953
Genes Whose Gain or Loss of Function Changes Type 1, 2A, 2X, or 2B Muscle Fibre Proportions in Mice-A Systematic Review., PMID:36361732
Thyroid Hormone Receptor β Knockdown Reduces Suppression of Progestins by Activating the mTOR Pathway in Endometrial Cancer Cells., PMID:36293372
Engineering Escherichia coli for l-homoserine production., PMID:36284486
Altricial Bird Early-Stage Embryos Express the Molecular "Machinery" to Respond to and Modulate Maternal Thyroid Hormone Cues., PMID:36240021
Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions., PMID:36217307
LEDGF is a new growth factor in fetal serum., PMID:35970411
A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice., PMID:35700264
Overexpression of the key genes in the biosynthetic pathways of lipid A and peptidoglycan in Escherichia coli., PMID:35644907
Proteomic Analysis of the Intestinal Resistance to Thyroid Hormone Mouse Model With Thyroid Hormone Receptor Alpha Mutations., PMID:35574030
What is the Role of Thyroid Hormone Receptor Alpha 2 (TRα2) in Human Physiology?, PMID:35255520
Molecular genetic approaches to decrease the uncontrolled misincorporation of non-canonical branched chain amino acids into recombinant mini-proinsulin expressed in Escherichia coli., PMID:35246127
T3 Promotes Glioma Cell Senescence and Apoptosis via THRA and THRB., PMID:34936295
Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores., PMID:34916557
Tanshinone IIA suppresses the progression of lung adenocarcinoma through regulating CCNA2-CDK2 complex and AURKA/PLK1 pathway., PMID:34880385
mRNA expression of specific HER ligands and their association with clinical outcome in patients with metastatic breast cancer treated with trastuzumab., PMID:34868360
Effect assessment of reclaimed waters and carbamazepine exposure on the thyroid axis of Xenopus laevis: Gene expression modifications., PMID:34563849
3,3',5-Triiodothyroacetic acid (TRIAC) induces embryonic ζ-globin expression via thyroid hormone receptor α., PMID:34174920
Single-Cell Transcriptome Profiling of Thyroid Hormone Effectors in the Human Fetal Neocortex: Expression of SLCO1C1, DIO2, and THRB in Specific Cell Types., PMID:34114484
For research use only. Not for human or drug use.
