Catalog No.
RHF90602
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Phospholipase C-beta-3, PLC-beta-3, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, Phosphoinositide phospholipase C-beta-3, PLCB3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q01970
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2C06
Cetuximab inhibits colorectal cancer development through inactivating the Wnt/β-catenin pathway and modulating PLCB3 expression., PMID:38724565
CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling., PMID:27191743
Short Stat5-interacting peptide derived from phospholipase C-β3 inhibits hematopoietic cell proliferation and myeloid differentiation., PMID:21949826
A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells., PMID:19592614
Sphingosine 1-phosphate-induced signal transduction in cat esophagus smooth muscle cells., PMID:16511346
Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation., PMID:15174099
1alpha,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-beta activity via phospholipase A2-dependent production of lysophospholipid., PMID:12798493
Subcellular localization of phospholipase C isoforms in vascular smooth muscle., PMID:12176394
Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction., PMID:11346454
Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4., PMID:11050147
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction., PMID:10669417
Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium., PMID:10570481
Activation of phospholipase C-beta1 via Galphaq/11 during calcium mobilization by calcitonin gene-related peptide., PMID:9685362
Gastrin induces IP3 formation through phospholipase C gamma 1 and pp60c-src kinase., PMID:9437736
Synthetic peptides containing a BXBXXXB(B) motif activate phospholipase C-beta1., PMID:9307015
Distribution of phospholipase C isozymes in normal human lung tissue and their immunohistochemical localization., PMID:8878798