Catalog No.
YHC83801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu205-Ser451
Predicted molecular weight
29.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10826
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Retinoic acid receptor beta, Nuclear receptor subfamily 1 group B member 2, RARB, HBV-activated protein, RAR-beta, RAR-epsilon, NR1B2, HAP
Effect of MiRNA 204-5P Mimics and Lipopolysaccharide-Induced Inflammation on Transcription Factor Levels, Cell Maintenance, and Retinoic Acid Signaling in Primary Limbal Epithelial Cells., PMID:40332443
Retinoic Acid Receptor Alpha- and Beta-Mediated Signaling Regulates Conjunctival Epithelial Cell Keratinization., PMID:40314655
A novel family of beta mixture models for the differential analysis of DNA methylation data: An application to prostate cancer., PMID:39661598
Detection of Genetic Variations in Children with Tetralogy of Fallot Using Whole Exome Sequencing Technology Integrated Bioinformatics Analysis., PMID:39653367
A De Novo Noncoding RARB Variant Associated with Complex Microphthalmia Alters a Putative Regulatory Element., PMID:39450403
TMT-based quantitative proteomic analysis of IBDV-infected CEF cells reveals a favorable role of chicken IRF10 in IBDV replication via suppressing type-I interferon expression., PMID:39442197
Valencene as a novel potential downregulator of THRB in NSCLC: network pharmacology, molecular docking, molecular dynamics simulation, ADMET analysis, and in vitro analysis., PMID:39425858
Successfully treatment of PLZF-RARα positive acute promyelocytic leukemia by Venetoclax combining with decitabine: a case report and literature review., PMID:39279268
Single-nucleus RNA sequencing reveals cell types, genes, and regulatory factors influencing melanogenesis in the breast muscle of Xuefeng black-bone chicken., PMID:39278114
Unveiling the role of RARs in stomach adenocarcinoma: clinical implications and prognostic biomarkers., PMID:39262490
RARB associated with MSI, affects progression and prognosis of gastric cancer., PMID:39179979
miR-190 restores the innate immune homeostasis of Drosophila by directly inhibiting Tab2 in Imd pathway., PMID:39084397
Alteration of Gene Expression in Pathological Keratinization of the Ocular Surface., PMID:38935029
A HNRNPC::RARB variant of acute promyelocytic leukemia with concurrent myeloid sarcoma of the spine., PMID:38864905
GSK-126 Enhances All-Trans-Retinoic Acid (ATRA) Response in Hepatocellular Carcinoma (HCC) by Upregulating RARG Expression., PMID:38798263
Inflammasome-related gene signatures as prognostic biomarkers in osteosarcoma., PMID:38742843
A founder variant expands the phenotype of WNT7B-related PDAC syndrome., PMID:38417950
Genetics and measles, mumps and rubella vaccine response in childhood and adolescence-A systematic review., PMID:38157324
Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment., PMID:37947765
Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States., PMID:37932662
In vitro regulation of fibroblast growth factor 23 by 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D synthesized by osteocyte-like MC3T3-E1 cells., PMID:37796032
Impaired bone morphogenetic protein signaling pathways disrupt decidualization in endometriosis., PMID:37790548
Combination of DNA methylation biomarkers with multiparametric magnetic resonance and ultrasound imaging fusion biopsy to detect the local spread of prostate cancer., PMID:37614027
Promoter hypermethylation of RARB and GSTP1 genes in plasma cell-free DNA as breast cancer biomarkers in Peruvian women., PMID:37548362
Am80, a retinoic acid receptor agonist, activates the cardiomyocyte cell cycle and enhances engraftment in the heart., PMID:37451261
DNA Methylation of Genes Participating in Hepatic Metabolisms and Function in Fetal Calf Liver Is Altered by Maternal Undernutrition during Gestation., PMID:37445858
Exploring the interactions of antihistamine with retinoic acid receptor beta (RARB) by molecular dynamics simulations and genome-wide meta-analysis., PMID:37331258
De novo retinoic acid receptor beta (RARB) variant associated with microphthalmia and dystonia., PMID:37321544
Clinical and genomic characterization of an ATRA-insensitive acute promyelocytic leukemia variant with a FNDC3B::RARB fusion., PMID:37283355
Report of PRPF19 as a novel partner of RARG and the recurrence of interposition-type fusion in variant acute promyelocytic leukemia., PMID:37132198
Clinical and functional heterogeneity associated with the disruption of retinoic acid receptor beta., PMID:37092537
Epigenetics regulation of prostate cancer: Biomarker and therapeutic potential., PMID:37032230
Molecular Heterogeneity of Pediatric AML with Atypical Promyelocytes Accumulation in Children-A Single Center Experience., PMID:36980947
[Childhood acute promyelocytic leukemia (APL) with TBL1XR1-RARB fusion: a case report]., PMID:36709161
Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway., PMID:36681687
Muscle Regeneration in Holothurians without the Upregulation of Muscle Genes., PMID:36555677
Copy number variations analysis in a cohort of 47 fetuses and newborns with congenital diaphragmatic hernia., PMID:36403094
All-trans retinoic acid (ATRA) regulates key genes in the RARG-TOP2B pathway and reduces anthracycline-induced cardiotoxicity., PMID:36331922
Bisulfite-Free and Single-Base Resolution Detection of Epigenetic DNA Modification of 5-Methylcytosine by Methyltransferase-Directed Labeling with APOBEC3A Deamination Sequencing., PMID:36280344
Epigenetic regulation of RARB overcomes the radio-resistance of colorectal carcinoma cells via cancer stem cells., PMID:36214504
Treatment of STAT5b-RARA positive acute promyelocytic leukemia by Venetoclax combining with homoharringtonine, cytarabine: A case report and literature review., PMID:35957665
Retinoid metabolism: new insights., PMID:35900851
Bi-allelic variants in WNT7B disrupt the development of multiple organs in humans., PMID:35790350
Deleted in lymphocytic leukemia 2 induces retinoic acid receptor beta promoter methylation and mitogen activated kinase-like protein activation to enhance viability and mobility of colorectal cancer cells., PMID:35611845
A short report of novel RARG-HNRNPM fusion gene in resembling acute promyelocytic leukemia., PMID:35544458
Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example., PMID:35483669
All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells., PMID:35464301
Correlations between histological characterizations and methylation statuses of tumour suppressor genes in Wilms' tumours., PMID:35436013
Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease., PMID:35275975
Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity., PMID:34706256
For research use only. Not for human or drug use.
