Catalog No.
RHF61202
Species reactivity
Human, Mouse, Rat, Hamster
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
Replication protein C, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, RP-C, PP2A-alpha, PPP2CA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P67775
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2A75
Measurement of Microcystin and Nodularin Activity in Human Urine by Immunocapture-Protein Phosphatase 2A Assay., PMID:31847123
Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium., PMID:29500169
Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair., PMID:25245035
Over one-third of African-American MGUS and multiple myeloma patients are carriers of hyperphosphorylated paratarg-7, an autosomal dominantly inherited risk factor for MGUS/MM., PMID:24443359
NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function., PMID:23921553
Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups., PMID:21590681
BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer., PMID:19711341
Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1., PMID:19622840
Cantharidin-induced mitotic arrest is associated with the formation of aberrant mitotic spindles and lagging chromosomes resulting, in part, from the suppression of PP2Aalpha., PMID:17121919
On the contractile function of protein phosphatases in isolated human coronary arteries., PMID:10551284
Molecular basis of alpha-tocopherol control of smooth muscle cell proliferation., PMID:9523023
Characterization of the PP2A alpha gene mutation in okadaic acid-resistant variants of CHO-K1 cells., PMID:7937753
Down-regulation by retinoic acid of the catalytic subunit of protein phosphatase type 2A during granulocytic differentiation of HL-60 cells., PMID:8386680
PPX, a novel protein serine/threonine phosphatase localized to centrosomes., PMID:8384557
For research use only. Not for human or drug use.
