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Anti-Histone H4 Antibody (R2A46)

Catalog #:   RHF53204 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: P62805
Overview

Catalog No.

RHF53204

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000

Target

HIST1H4D, HIST2H4A, H4FE, H4FO, H4/D, H4/A, HIST1H4E, HIST1H4F, H4FG, HIST1H4L, H4FD, H4/H, HIST1H4B, HIST1H4I, H4FN, HIST1H4C, H4FI, H4FC, H4/C, H4/E, Histone H4, H4/G, H4/O, H4FB, H4FK, H4/M, H4/B, H4C1, HIST2H4, H4F2, HIST2H4B, HIST1H4A, HIST1H4J, H4/N, H4FH, H4/I, H4/J, H4/K, H4FJ, HIST1H4H, HIST1H4K, HIST4H4, H4FM, H4FA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P62805

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2A46

Data Image
References

Immune-modulatory effects of Spindlin-1 inhibitors., PMID:40512144

Mechanistic insights into the stimulation of the histone H3K9 methyltransferase Clr4 by proximal H3K14 ubiquitination., PMID:40446033

Acetylation profiling by Iseq-Kac reveals insights into HSC aging and lineage decision., PMID:40419771

Radiation-Induced Gamma-H2AX Foci Staining and Analysis., PMID:40418470

Anti-DAMP therapies for acute inflammation., PMID:40406124

Epigenomic Profiling of Histone Posttranslational Modifications in Frozen Cancer Tissue Using CUT&RUN., PMID:40402458

Tissue-specific localization of the ING4 targeting subunit of the HBO1 histone acetyltransferase in the cytoplasm and nucleus of secretory cells., PMID:40402282

Synergistic inhibition of CitH3 and S100A8/A9: A novel therapeutic strategy for mitigating sepsis-induced inflammation and lung injury., PMID:40390290

ATAD2 bromodomain in cancer therapy: current status and future perspectives., PMID:40334884

Surgical and radiological outcomes of giant cell tumor of the bone: prognostic value of Campanacci grading and selective use of denosumab., PMID:40317378

Neutrophil extracellular traps aggravate placental injury in OAPS by facilitating activation of BNIP3 mediated mitophagy., PMID:40286883

Detection of γ-H2A.X for Rapid Assessment of Genotoxic Agent-induced Double-strand DNA Breaks by Immunofluorescence., PMID:40257558

SIRT3 Functions as an Eraser of Histone H3K9 Lactylation to Modulate Transcription for Inhibiting the Progression of Esophageal Cancer., PMID:40252727

Valproic acid promotes transcriptional activation of Drd2 by mediating histone acetylation to inhibit the mTOR-Pttg1 signaling axis and exerts anti-PitNETs activity., PMID:40220407

The mechanism of EZH2/H3K27me3 downregulating CXCL10 to affect CD8+ T cell exhaustion to participate in the transformation from myelodysplastic syndrome to acute myeloid leukaemia., PMID:40201935

Multiplexed cytometry for single cell chemical biology., PMID:40180452

Platelet activating histone/antihistone IgG complexes in anti-PF4 negative thrombosis and thrombocytopenia syndrome., PMID:40179418

Immune Response and Production of Abzymes in Patients with Autoimmune and Neurodegenerative Diseases., PMID:40164167

Mind Your Spectra: Points to be Aware of When Validating the Identification of Isobaric Histone Peptidoforms., PMID:40163023

PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth., PMID:40132583

Role of H3F3A (H3G34W) antibody in the diagnosis of giant cell tumour of bone in the paediatric age group., PMID:40107010

Targeted DamID detects cell-type-specific histone modifications in intact tissues or organisms., PMID:40067796

Appraising histone H4 lysine 5 lactylation as a novel biomarker in breast cancer., PMID:40065036

Inhibition of EETosis with an anti-citrullinated histone antibody: a novel therapeutic approach for eosinophilic inflammatory disorders., PMID:40051617

Hepatocytes and Hepatic Stellate Cells Carry Different Levels of DNA Damage due to Their Sensitivity to Oxidative Stress in Chronic Hepatitis B., PMID:39991880

Histone H3 K4 trimethylation occurs mainly at the origins of polycistronic transcription in the genome of Leishmania infantum promastigotes and intracellular amastigotes., PMID:39979847

The effect of chemical fixation with paraformaldehyde, glutardialdehyde or methanol on immunofluorescence staining of neutrophils and neutrophil extracellular traps., PMID:39967319

The added value of coupling anti-dsDNA and anti-chromatin antibodies in follow-up monitoring of systemic lupus erythematosus patients., PMID:39917317

SDG8 and HUB2 depositing euchromatin histone marks play important roles in meiosis and crossing-over regulation., PMID:39916632

Protocol for visualizing the chromatin assembly properties of epigenetic protein complexes via an HTM module-mediated artificial tethering system., PMID:39879359

Mineral Stress Drives Loss of Heterochromatin: An Early Harbinger of Vascular Inflammaging and Calcification., PMID:39840455

T-2 toxin triggers immunotoxic effects in goats by inducing ferroptosis and neutrophil extracellular traps., PMID:39832565

Distinct structural and functional heterochromatin partitioning of lamin B1 and lamin B2 revealed using genome-wide nicking enzyme epitope targeted DNA sequencing., PMID:39817518

Chemical proteomic profiling of lysine crotonylation using minimalist bioorthogonal probes in mammalian cells., PMID:39817196

Binding mode-guided development of high-performance antibodies targeting site-specific posttranslational modifications., PMID:39793060

Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression., PMID:39789354

Quantitative Analysis of Nonhistone Lysine Methylation Sites and Lysine Demethylases in Breast Cancer Cell Lines., PMID:39778878

By activating endothelium histone H4 mediates oleic acid-induced acute respiratory distress syndrome., PMID:39757148

Quantification of Citrullinated Histone H3 as a Marker for Neutrophil Extracellular Traps Correlated to Clinical Characteristics of Patients with Systemic Lupus Erythematosus., PMID:39752730

Monoallelic expression can govern penetrance of inborn errors of immunity., PMID:39743591

Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling., PMID:39709039

Selective Recruitment of a Synthetic Histone Acetyltransferase Can Boost CHO Cell Productivity., PMID:39655408

Aberrantly Expressed Mitochondrial Lipid Kinase, AGK, Activates JAK2-Histone H3 Axis and BCR Signal: A Mechanistic Study with Implication in CLL Therapy., PMID:39636206

Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation., PMID:39627218

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion., PMID:39561764

RADIP technology comprehensively identifies H3K27me3-associated RNA-chromatin interactions., PMID:39558168

Histone H1 kills MRSA., PMID:39546397

Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1., PMID:39545415

Comparison of cell type and disease subset chromatin modifications in SLE., PMID:39543716

Genome-Wide Profiling of Histone Modifications in Fission Yeast Using CUT&Tag., PMID:39527210

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-Histone H4 Antibody (R2A46) [RHF53204]
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