Catalog No.
YHC81101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile17-Asn314
Predicted molecular weight
36.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10451
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Osteopontin, BNSP, Uropontin, OPN, SPP-1, Secreted phosphoprotein 1, Bone sialoprotein 1, Nephropontin, Urinary stone protein, SPP1
Sulfonated polyetheretherketone enriched with MXene V2C promotes bone formation via WNT/β-catenin signaling in bone marrow mesenchymal stem cells., PMID:40514103
Circulating protein biomarkers and their association with vulnerable plaque characteristics - a PROSPECT II substudy., PMID:40503438
Serum and Urine Biomarkers Can Predict Outcomes after Osteochondral Allograft Transplantation in the Knee., PMID:40499917
Osteopontin levels in the serum reflect anatomical disease progression in patients with amyotrophic lateral sclerosis., PMID:40493233
Alkaline Treatment Enhances the Anti-inflammatory and Reparative Potential of Dentin Matrix Proteins in Inflamed Pulp., PMID:40484223
GYY4137, a Slow-Releasing Hydrogen Sulfide Donor, Attenuates Skeletal Muscle Abnormalities in a Murine Model of Duchenne Muscular Dystrophy., PMID:40476490
Associations between seminal plasma osteopontin level and sperm motility in infertile men with asthenozoospermia., PMID:40458181
Histopathological and immunohistochemical characterization of pulp tissue reaction to ACTIVA BioACTIVE base/liner in primary teeth pulpotomy: a randomized clinical trial., PMID:40457274
Porphyromonas gingivalis induced DNA oxidative stress damage by iron overload to deplete CTCF expression and prevent osteogenic differentiation of periodontal ligament stem cells., PMID:40455363
The link between osteoporosis and cardiovascular diseases: a review of shared mechanisms, risk factors, and therapeutic approaches., PMID:40455217
Expression and Distribution of Osteopontin, Osteocalcin and Osteonectin in the Bull Reproductive Tract., PMID:40444545
Bone mineralization and the effects of elevated osteopontin: from symmetry-breaking foci to 3D space-filling tessellation., PMID:40439195
A green synthetic nanosilver photo-crosslinked injectable gelatin/hyaluronic acid hydrogel for infected cranial defect repair., PMID:40436171
Fibroblast growth factor 2 stimulates differentiation of mechanically-stressed human periodontal ligament fibroblasts into cementoblasts., PMID:40434329
Tartaric acid-branched polyethyleneimine carbon dots promote repair of bone defect via osteogenic differentiation., PMID:40416649
Enhancing radiosensitivity of osteosarcoma by ITGB3 knockdown: a mechanism linked to enhanced osteogenic differentiation status through JNK/c-JUN/RUNX2 pathway activation., PMID:40410897
An electrochemically charged nanoengineered bioelectronic immunosensing device for osteopontin detection in serum samples., PMID:40405794
Osteopontin protects from ovalbumin-induced asthma by preserving the microbiome and the intestinal barrier function., PMID:40401951
Osteopontin regulates right ventricular failure through integrin ανβ3/PERK/CHOP-dependent inflammatory and apoptotic pathways., PMID:40396173
Endothelial TIE2 Mutation Induced Contraction Deficiency of Vascular Smooth Muscle Cells via Phenotypic Transition Regulation in Venous Malformations., PMID:40386049
M2 macrophage-targeted metal-polyphenol networks (MPNs) for OPN siRNA delivery and idiopathic pulmonary fibrosis therapy., PMID:40383161
A serum biomarker panel and miniarray detection system for tracking disease activity and flare risk in lupus nephritis., PMID:40375995
[Effect of stretch on taurine upregulated gene 1-mediated miR-545-3p/cannbinoida receptor 2 pathway regulating distraction osteogenesis in rats]., PMID:40368863
BDNF alleviates senescence and enhances osteogenic differentiation in bone marrow mesenchymal stem cells via the TrkB/PI3K/AKT pathway., PMID:40367890
Acetylcholine Sustains LNCaP Prostate Cancer Cell Migration, Invasion and Proliferation Through Glyoxalase 1/MG-H1 Axis with the Involvement of Osteopontin., PMID:40362346
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury., PMID:40356152
Dysregulation of miR-106a-5p/PTEN axis associated with progression and diagnostic of postmenopausal osteoporosis., PMID:40355896
TSAb inhibits osteogenic differentiation of MC3T3-E1 cells and exacerbates bone loss in Graves' disease mice., PMID:40354515
Recent Progression and Treatment Approaches for the Kidney Stone Management., PMID:40353475
[Role of miR-140-5p/BCL2L1 in apoptosis and autophagy of HFOB1.19 and effect of Bushen Jianpi Huoxue Decoction]., PMID:40350835
Pro-Atherosclerotic Effects of Osteopontin Is Contributed to Promoting Foam Cell Formation Derived From VSMCs by Inhibiting Cholesterol Efflux., PMID:40332823
Multi - dimensional mechanism analysis of Choerospondias axillaris (Roxb.) Burtt et Hill in treating kidney stones: network pharmacology, molecular docking and in vitro experimental verification., PMID:40331191
Ability of SPP1 to Alleviate Post-Intracerebral Hemorrhage Ferroptosis via Nrf2/HO1 Pathway., PMID:40321093
Microparticles of Pereskia aculeata miller mucilage and sodium alginate for the encapsulation of Lactobacillus acidophilus ATCC 4356., PMID:40318711
Functions of secretory calcium-binding phosphoproteins in dental mineralization., PMID:40318225
Exercise ameliorates cardiac injury induced by nandrolone decanoate through downregulation of osteopontin and mTOR expressions., PMID:40315693
Curcumin Inhibits Lipopolysaccharide-Induced Inflammation Through the HMGB1/NF-κB Signaling Pathway to Promote the Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells., PMID:40310592
Synergistic effect of 2'-fucosyllactose and osteopontin on intestinal mucosal immunity injury., PMID:40308162
Mitochondrial Oxygen Consumption and Immunocytochemistry of Human Dental Pulp Stem Cell Following 808 nm PBM Therapy: A 3D Cell Culture Study., PMID:40294940
Orai1 Participates in Coronary Artery Dysfunction Caused by Hypertension via Regulating Smooth Muscle Cell Phenotype Transformation., PMID:40293813
Type IV collagen, carcinoembryonic antigen, osteopontin, and hepatocyte growth factor as biomarkers for liver metastatic colorectal cancer., PMID:40289465
Plasma osteopontin levels are associated with the risk of future incident venous thromboembolism-the Trøndelag Health Study (HUNT)., PMID:40288683
Osteopontin in Chronic Inflammatory Diseases: Mechanisms, Biomarker Potential, and Therapeutic Strategies., PMID:40282293
Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts., PMID:40280123
Post-ESWL urinary osteopontin level and ion-activity product of calcium oxalate are associated with stone recurrence after 5-year follow-up., PMID:40275250
Resveratrol exerts antiviral activity against pseudorabies virus through regulation of the OPN-ERK/JNK-IL-1β signaling axis., PMID:40274095
Orthodontic treatment after occlusal intervention balances osteoblast and osteoclast differentiation via SIRT1 beta catenin signaling in rats with hypofunctional occlusion., PMID:40263606
Gouqi-derived Nanovesicles (GqDNVs) promoted MC3T3-E1 cells proliferation and improve fracture healing., PMID:40252435
MIR155HG suppresses the osteogenic differentiation of bone marrow mesenchymal stem cells through regulating miR-155-5p and DKK1 expression., PMID:40251598
IGF-1 signaling pathway activation promotes axonal regeneration and repair: A mechanism study on catalpol-induced functional recovery after ischemic stroke., PMID:40245961