Catalog No.
RHF28001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
Toll/interleukin-1 receptor domain-containing adapter protein, TIRAP, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MAL, MyD88-2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P58753
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Z68
Revealing the Mechanism of Buzhong Yiqi Tang in Ameliorating Autoimmune Thyroiditis via the Toll-like Receptor Pathway., PMID:40033498
Requirement of scavenger receptors for activation of the IRF-3/IFN-β/STAT-1 pathway in TLR4-mediated production of NO by LPS-activated macrophages., PMID:37059259
Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapy., PMID:36531688
Effects of substituting soybean meal with corn on immune function and gene expression of gut TLR4 pathway of growing goats., PMID:35186490
Determination of MYD88L265P mutation fraction in IgM monoclonal gammopathies., PMID:34788399
Case report: hepatitis in a child infected with SARS-CoV-2 presenting toll-like receptor 7 Gln11Leu single nucleotide polymorphism., PMID:34482844
RAGE silencing deters CML-AGE induced inflammation and TLR4 expression in endothelial cells., PMID:33639133
Genetic Basis of Response of Ghanaian Local Chickens to Infection With a Lentogenic Newcastle Disease Virus., PMID:32849779
Genetic Analyses of Tanzanian Local Chicken Ecotypes Challenged with Newcastle Disease Virus., PMID:31319636
Genetics and Genomic Regions Affecting Response to Newcastle Disease Virus Infection under Heat Stress in Layer Chickens., PMID:30669351
Association of an IRF3 putative functional uORF variant with resistance to Brucella infection: A candidate gene based analysis of InDel polymorphisms in goats., PMID:30477986
Innate Immunity Induced by the Major Allergen Alt a 1 From the Fungus Alternaria Is Dependent Upon Toll-Like Receptors 2/4 in Human Lung Epithelial Cells., PMID:30100902
SslE (YghJ), a Cell-Associated and Secreted Lipoprotein of Neonatal Septicemic Escherichia coli, Induces Toll-Like Receptor 2-Dependent Macrophage Activation and Proinflammation through NF-κB and MAP Kinase Signaling., PMID:29891541
Associations between functional polymorphisms and response to biological treatment in Danish patients with psoriasis., PMID:28696418
When TLRs fail, IgG has your back., PMID:28330862
Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity., PMID:28235196
FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression., PMID:26582197
Methylation of Cervical Neoplastic Cells Infected With Human Papillomavirus 16., PMID:26552048
CADM1 and MAL methylation status in cervical scrapes is representative of the most severe underlying lesion in women with multiple cervical biopsies., PMID:26219541
Effects of Pholiota nameko polysaccharide on NF-κB pathway of murine bone marrow-derived dendritic cells., PMID:25812973
Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjögren's syndrome?, PMID:25802401
Specific binding of the WASP N-terminal domain to Btk is critical for TLR2 signaling in macrophages., PMID:25213142
Association of TLR4 (D299G, T399I), TLR9 -1486T>C, TIRAP S180L and TNF-α promoter (-1031, -863, -857) polymorphisms with risk for systemic lupus erythematosus among South Indians., PMID:25182168
Polymorphisms of endotoxin pathway and endotoxin exposure: in vitro IgE synthesis and replication in a birth cohort., PMID:25102764
S100A proteins as molecular targets in the ocular surface inflammatory diseases., PMID:24439044
TLR2 and TLR4 in autoimmune diseases: a comprehensive review., PMID:24352680
Anti-CD14 antibody reduces LPS responsiveness via TLR4 internalization in human monocytes., PMID:24172224
Sarm1-mediated axon degeneration requires both SAM and TIR interactions., PMID:23946415
Anti-NMDA receptor encephalitis in children: the disorder, its diagnosis, and treatment., PMID:23622333
Human CD27+IgM+IgD+ B cells: T-cell or TLR-dependent?, PMID:23243153
IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients., PMID:23002119
Cetuximab-mediated tumor regression depends on innate and adaptive immune responses., PMID:22990672
Human cytomegalovirus induces TLR4 signaling components in monocytes altering TIRAP, TRAM and downstream interferon-beta and TNF-alpha expression., PMID:22970235
Mutation analysis of NF-κB signal pathway-related genes in ocular MALT lymphoma., PMID:22808296
A novel exopolysaccharide from the biofilm of Thermus aquaticus YT-1 induces the immune response through Toll-like receptor 2., PMID:21454596
Neisseria meningitidis capsular polysaccharides induce inflammatory responses via TLR2 and TLR4-MD-2., PMID:21191086
Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis., PMID:20112371
Mycoplasma genitalium-derived lipid-associated membrane proteins activate NF-kappaB through toll-like receptors 1, 2, and 6 and CD14 in a MyD88-dependent pathway., PMID:19793902
Regulation of TLR2 expression and function in human airway epithelial cells., PMID:19513781
Association of interacting genes in the toll-like receptor signaling pathway and the antibody response to pertussis vaccination., PMID:18987746
The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to, or severity of, rheumatoid arthritis., PMID:18180278
Expression of Toll/IL-1R domain-containing adaptor protein (TIRAP) is detrimental to primary clearance of Salmonella and is not required for the generation of protective immunity., PMID:18096248
Protein kinase Cdelta binds TIRAP/Mal to participate in TLR signaling., PMID:17161867
Activation of complement C3, C5, and C9 genes in tumors treated by photodynamic therapy., PMID:16947020
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals., PMID:16886064
Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5., PMID:16239509
Preferential expression and function of Toll-like receptor 3 in human astrocytes., PMID:15652398
TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages., PMID:11896392
For research use only. Not for human or drug use.
