Catalog No.
YHC80401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser68-Glu173
Predicted molecular weight
14.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10276
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RARA, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1, RAR-alpha, NR1B1
Interaction of neuropilin-1 and hepatocyte growth factor/C-Met pathway in liver fibrosis progression in hepatocyte-specific NRP-1 knockout mice., PMID:40419692
Effect of MiRNA 204-5P Mimics and Lipopolysaccharide-Induced Inflammation on Transcription Factor Levels, Cell Maintenance, and Retinoic Acid Signaling in Primary Limbal Epithelial Cells., PMID:40332443
Retinoic Acid Receptor Alpha- and Beta-Mediated Signaling Regulates Conjunctival Epithelial Cell Keratinization., PMID:40314655
Spermatogenesis advancement in pre-pubertal meagre Argyrosomus regius treated with recombinant gonadotropins., PMID:40301651
Immunophenotypic Profiling of Acute Promyelocytic Leukemia: Insights From a Large Cohort., PMID:40251942
[TTMV::RARA positive acute promyelocytic leukemia in a child]., PMID:40240024
HLA-DR positive acute promyelocytic leukaemia (APML) with cryptic PML::RARA fusion., PMID:40214855
The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid., PMID:40194363
Transcriptomic profile induced by calcitriol in CaSki human cervical cancer cell line., PMID:40168262
Genomic regions occupied by both RARα and VDR are involved in the convergence and cooperation of retinoid and vitamin D signaling pathways., PMID:40167329
Daxx Variation as a Potential Predictive Marker of the Therapeutic Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer., PMID:40130316
SERS-Based Assessment of DNA Methylation for the Evaluation of Measurable Residual Disease in Acute Promyelocytic Leukaemia., PMID:40042091
Meg3-NONO-RAR axis mediates RA pathway activation in TCDD-induced cleft palate., PMID:40024514
Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities., PMID:40022879
DNA methylation patterns contribute to changes of cellular differentiation pathways in leukocytes with LOY from patients with Alzheimer´s disease., PMID:39998604
Gene Fusion-Driven Cutaneous Adnexal Neoplasms: An Updated Review Emphasizing Molecular Characteristics., PMID:39912629
Turning over new ideas in human skeletal muscle proteostasis: What do we know and where to from here?, PMID:39910909
Evaluation of 3D-Printed Microfluidic Structures for Use in AML-Specific Biomarker Detection of PML::RARA., PMID:39859217
Utilization of RT-PCR and Optical Genome Mapping in Acute Promyelocytic Leukemia with Cryptic PML::RARA Rearrangement: A Case Discussion and Systemic Literature Review., PMID:39858554
Telomere shortening in donor cell-derived acute promyelocytic leukemia after allogeneic hematopoietic stem cell transplantation: a case report., PMID:39841197
Zebrafish modeling of atypical PML-RARA isoform from acute promyelocytic leukemia patient and its implications for clinical treatment., PMID:39836190
Predictive modelling of acute Promyelocytic leukaemia resistance to retinoic acid therapy., PMID:39807666
Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy., PMID:39807332
Signaling via retinoic acid receptors mediates decidual angiogenesis in mice and human stromal cell decidualization., PMID:39777800
Rapid Detection of PML::RARA Fusions in Acute Promyelocytic Leukemia: CRISPR/Cas9 Nanopore Sequencing with Adaptive Sampling., PMID:39766302
Effects of two different dexamethasone dosing regimens on ventilator-free days and long-term mortality in COVID-19 patients with moderate-to-severe ARDS: the REMED randomized clinical trial., PMID:39710693
Epigenetic Therapies., PMID:39694694
Genomic characteristics of PD-L1-Induced resistance to EGFR-TKIs in lung adenocarcinoma., PMID:39691079
Next-generation sequencing RNA fusion panel for the diagnosis of haematological malignancies., PMID:39672769
Phenotypic Profiling of Tigecycline-resistant Klebsiella pneumoniae Strains Induced In vitro., PMID:39671135
CDK9 recruits HUWE1 to degrade RARα and offers therapeutic opportunities for cutaneous T-cell lymphoma., PMID:39632829
Menstrual cycle phase does not influence muscle protein synthesis or whole-body myofibrillar proteolysis in response to resistance exercise., PMID:39630025
RAPID-CRISPR: highly sensitive diagnostic assay for detection of PML::RARA isoforms in acute promyelocytic leukemia., PMID:39622167
First case of acute promyelocytic leukemia with TFG-RARA achieved complete remission treated with venetoclax and all-trans retinoic acid., PMID:39606904
Optical Genome Mapping Reveals Complex and Cryptic Rearrangement Involving PML::RARA Fusion in Acute Promyelocytic Leukemia., PMID:39596602
Fluorescent Aerolysin (FLAER) Binding Is Abnormally Low in the Clonal Precursors of Acute Leukemias, with Binding Particularly Low or Absent in Acute Promyelocytic Leukemia., PMID:39595968
Long-term follow-up of a phase 2 study of all-trans retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin in acute promyelocytic leukemia., PMID:39584789
EZH2 inhibition sensitizes retinoic acid-driven senescence in synovial sarcoma., PMID:39550391
Impact of Simultaneous Presence of Multiple PML-RARA Isoforms on Phenotype in Patients with Acute Promyelocytic Leukaemia., PMID:39491447
Putative mechanisms of primary resistance to EGFR-targeted therapies: A retrospective study., PMID:39490204
Imatinib is effective in some PDGFRA/B-negative hypereosinophilic syndromes: A step closer to unveiling underlying mechanisms., PMID:39468717
Acute myeloid leukemia with NPM1, IDH2, and SETD2 mutations mimicking acute promyelocytic leukemia: A case report and literature review., PMID:39432585
Valencene as a novel potential downregulator of THRB in NSCLC: network pharmacology, molecular docking, molecular dynamics simulation, ADMET analysis, and in vitro analysis., PMID:39425858
Phase II trial of imatinib mesylate in patients with PDGFRA/B-negative hypereosinophilic syndrome., PMID:39389908
TTMV::RARA-positive acute promyelocytic leukemia with marrow necrosis and central nervous system involvement at disease recurrence., PMID:39343611
Phospholipase Cδ-4 (PLCδ4) Acts as a Nuclear Player to Influence Cyclin B Expression in the Embryonal Rhabdomyosarcoma Cell Lines RD and A204., PMID:39334946
Targeting ALDH1A1 to enhance the efficacy of KRAS-targeted therapy through ferroptosis., PMID:39317105
Unveiling the role of RARs in stomach adenocarcinoma: clinical implications and prognostic biomarkers., PMID:39262490
Tailored Digital PCR Follow-Up of Rare Fusion Transcripts after Initial Detection through RNA Sequencing in Hematological Malignancies., PMID:39182671
Critical variables regulating age-related anabolic responses to protein nutrition in skeletal muscle., PMID:39166128
For research use only. Not for human or drug use.
