Catalog No.
YHC80001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro595-Gly770
Predicted molecular weight
21.94 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10253
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GAA, Lysosomal alpha-glucosidase, Acid maltase, Aglucosidase alfa
Long-Read Sequencing Identifies Mosaic Sequence Variations in Friedreich's Ataxia-GAA Repeats., PMID:40507780
Partial Alpha-Tubulin Gene Amplification by Nested PCR in Fresh Biological Samples and Formalin-Fixed, Paraffin-Embedded Tissues for Paracoccidioides spp. Identification., PMID:40483612
Evaluating PSA dynamics for predicting androgen deprivation failure with a patient specific prostate cancer model., PMID:40456781
Guanidinoacetic Acid and Methionine Supplementation Improve the Growth Performance of Beef Cattle via Regulating the Antioxidant Levels and Protein and Lipid Metabolisms in Serum and Liver., PMID:40427441
Base editing of trinucleotide repeats that cause Huntington's disease and Friedreich's ataxia reduces somatic repeat expansions in patient cells and in mice., PMID:40419681
Creatine mitigates neurogenesis impairment caused by defective DcpS decapping., PMID:40410278
Effects of heterozygous SMG1 mutations on nonsense-mediated mRNA decay in human pluripotent stem cell model., PMID:40403878
Thermostable lamprey variable lymphocyte receptor antibody for detection of Plasmodium falciparum histidine rich protein-2., PMID:40382473
Comparison of Prostate-specific Membrane Antigen Reporting and Data System Version 1.0 versus 2.0 for Prostate Cancer Assessment., PMID:40377421
Therapeutic combination of L-ascorbic acid, N-acetylcysteine, and dimethyl fumarate in Friedreich's ataxia: insights from in vitro models., PMID:40375363
Comparative analysis of complete chloroplast genomes of Cousinia (Asteraceae) species., PMID:40365567
Comparative analysis of chloroplast genomes and phylogenetic relationships of different pitaya cultivars., PMID:40346528
Ganoderic acid A: an in-depth review of pharmacological effects and molecular docking analysis., PMID:40316150
An indirect competitive ELISA for determination of guanidine acetic acid in animal feed., PMID:40312435
Brain microvascular endothelial cells differentiated from a Friedreich's Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly permeable., PMID:40303283
MSH2 is not required for either maintenance of DNA methylation or repeat contraction at the FMR1 locus in fragile X syndrome or the FXN locus in Friedreich's ataxia., PMID:40296143
Guanidinoacetic acid in laying hen diets with varying dietary energy: Productivity, antioxidant status, yolk fatty acid profile, hepatic lipid metabolism, and gut health., PMID:40267570
Ganoderic acid a potentiates cisplatin's cytotoxicity on gallbladder cancer cells by promoting DNA damage and inhibiting cell stemness., PMID:40259397
Improving the treatment of Pompe disease with enzyme replacement therapy: current strategies and clinical evidence., PMID:40237692
Ganoderic Acid A Prevented Osteoporosis by Modulating the PIK3CA/p-Akt/TWIST1 Signaling Pathway., PMID:40236832
Biochemical and Genetic Testing of GAA in Over 30.000 Symptomatic Patients Suspected to Be Affected With Pompe Disease., PMID:40225932
Synergistic anti-inflammatory effects of Ganoderma lucidum polysaccharide and ganoderic acid A on LPS-induced RAW264.7 cells by inhibition of TLR4/NF-κB activation., PMID:40220822
Association of +67 G/A and -426 T/C Polymorphism in Eotaxin (CCL11) Gene with Psoriasis Phenotypes., PMID:40149440
LRPPRC confers enhanced oxidative phosphorylation metabolism in triple-negative breast cancer and represents a therapeutic target., PMID:40133967
Rare loss-of-function variants in HECTD2 and AKAP11 confer risk of bipolar disorder., PMID:40133559
High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models., PMID:40128218
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway., PMID:40054827
Late-onset vestibulocerebellar ataxia: clinical and genetic studies in a long follow-up series of 50 patients., PMID:40024931
Epigenetic Modulation Directs Recovery Post LASIK and SMILE Surgery: An Experimental Study., PMID:40003656
A stable GH31 α-glucosidase as a model system for the study of mutations leading to human glycogen storage disease type II., PMID:39995088
Frataxin deficiency and the pathology of Friedreich's Ataxia across tissues., PMID:39981684
Near-complete assembly and comprehensive annotation of the wheat Chinese Spring genome., PMID:39949061
Recognition Mechanism of RNA by TLR13: Structural Insights and Implications for Immune Activation., PMID:39938739
Clinical and genetic spectrums of Pompe disease in Duhok city, Kurdistan region, Iraq., PMID:39910942
Functional Characterization of Parallel Fiber-Purkinje Cell Synapses in Two Friedreich's Ataxia Mouse Models., PMID:39907933
Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA., PMID:39905333
Performance Responses and Fillet Quality of Rainbow Trout (Oncorhynchus mykiss) to Increasing Addition Levels of Dietary Supplementation of Guanidinoacetic Acid., PMID:39858267
Engineering of a lysosomal-targeted GAA enzyme., PMID:39846949
Recent Insights Into Wnt-Related tRNA-Derived Fragments (tRFs) in Human Diseases., PMID:39835731
A Real-World Data Analysis of Alglucosidase Alfa in the FDA Adverse Event Reporting System (FAERS) Database., PMID:39833603
NKAPL facilitates transcription pause-release and bridges elongation to initiation during meiosis exit., PMID:39824811
Complete mitochondrial genome assembly and comparative analysis of Colocasia esculenta., PMID:39819387
Ganoderic Acid A Alleviates Severe Acute Pancreatitis by Modulating Gut Homeostasis and Inhibiting TLR4-NLRP3 Signaling., PMID:39811933
Friedreich Ataxia: An (Almost) 30-Year History After Gene Discovery., PMID:39810753
Friedreich ataxia: what can we learn from non-GAA repeat mutations?, PMID:39810561
Integrated TWAS, GWAS, and RNAseq results identify candidate genes associated with reproductive traits in cows., PMID:39809816
Conservation agricultural practices promoted arbuscular mycorrhizal fungal colonization and glomalin content on sandy clay loam of southern India., PMID:39807493
Intestinal barrier function, caecal microbiota and growth performance of thermoneutral or heat stressed broiler chickens fed reduced crude protein diets supplemented with guanidinoacetic acid., PMID:39805251
Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease., PMID:39780163
For research use only. Not for human or drug use.
