Catalog No.
YHC79301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys28-Ile161
Predicted molecular weight
17.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10153
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Non-secretory ribonuclease, RNASE2, RNS2, Eosinophil-derived neurotoxin, EDN, Ribonuclease US, Ribonuclease 2, RNase UpI-2, RNase 2
Protease-activated receptor 2 and interleukin-13 receptor α1 activation is linked to eosinophilic chronic rhinosinusitis., PMID:40074076
RNA analysis of patients with benign and malignant pulmonary nodules., PMID:39822942
Identification of M2 macrophage-related genes for establishing a prognostic model in pancreatic cancer: FCGR3A as key gene., PMID:39574475
Exploring CD26-/lo subpopulations of lymphocytes in asthma phenotype and severity: A novel CD4+ T cell subset expressing archetypical granulocyte proteins., PMID:39319599
Elucidating common pathogenic transcriptional networks in infective endocarditis and sepsis: integrated insights from biomarker discovery and single-cell RNA sequencing., PMID:38332910
Integrating scRNA-seq to explore novel macrophage infiltration-associated biomarkers for diagnosis of heart failure., PMID:37974098
Antiviral effect of high-pressure nasal stimulation., PMID:37843339
The Pitaya Flower Tissue's Gene Differential Expression Analysis between Self-Incompatible and Self-Compatible Varieties for the Identification of Genes Involved in Self-Incompatibility Regulation., PMID:37511162
Identification of Shared Immune Cells and Immune-Related Co-Disease Genes in Chronic Heart Failure and Systemic Lupus Erythematosus Based on Transcriptome Sequencing., PMID:37408607
The Role of Eosinophil-Derived Neurotoxin and Vascular Endothelial Growth Factor in the Pathogenesis of Eosinophilic Asthma., PMID:37174726
RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication., PMID:37105176
Identification MNS1, FRZB, OGN, LUM, SERP1NA3 and FCN3 as the potential immune-related key genes involved in ischaemic cardiomyopathy by random forest and nomogram., PMID:36863704
Ribonuclease A Family Member 2 Promotes the Malignant Progression of Glioma Through the PI3K/Akt Signaling Pathway., PMID:35747836
Identification of novel genes influencing eosinophil-specific protein levels in asthma families., PMID:35671886
Construction and validation of a prognostic model of RNA binding proteins in clear cell renal carcinoma., PMID:35513791
Selective cleavage of ncRNA and antiviral activity by RNase2/EDN in THP1-induced macrophages., PMID:35347428
RNASE2 Mediates Age-Associated B Cell Expansion Through Monocyte Derived IL-10 in Patients With Systemic Lupus Erythematosus., PMID:35265065
Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia., PMID:35111390
Six RNA binding proteins (RBPs) related prognostic model predicts overall survival for clear cell renal cell carcinoma and is associated with immune infiltration., PMID:34420511
Cluster of highly expressed interferon-stimulated genes associate more with African ancestry than disease activity in patients with systemic lupus erythematosus. A systematic review of cross-sectional studies., PMID:34343626
Integrated Analysis of the Roles of RNA Binding Proteins and Their Prognostic Value in Clear Cell Renal Cell Carcinoma., PMID:34306592
Identification of a three-gene-based prognostic model in multiple myeloma using bioinformatics analysis., PMID:34249481
Development and validation of RNA binding protein-applied prediction model for gastric cancer., PMID:33589575
Integral Analysis of the RNA Binding Protein-associated Prognostic Model for Renal Cell Carcinoma., PMID:33456353
Development and validation of a prognostic model for kidney renal clear cell carcinoma based on RNA binding protein expression., PMID:33229623
Identification of a novel immune prognostic model in gastric cancer., PMID:32857339
Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2., PMID:32294405
Translation of mouse model to human gives insights into periodontitis etiology., PMID:32184465
Identification of key genes involved in myocardial infarction., PMID:31269974
Caught in a Trap? Proteomic Analysis of Neutrophil Extracellular Traps in Rheumatoid Arthritis and Systemic Lupus Erythematosus., PMID:30915077
Integrative approach identifies corticosteroid response variant in diverse populations with asthma., PMID:30367910
Comparative Proteomics Analysis of Urine Reveals Down-Regulation of Acute Phase Response Signaling and LXR/RXR Activation Pathways in Prostate Cancer., PMID:29286311
The genetically determined production of the alarmin eosinophil-derived neurotoxin is reduced in visceral leishmaniasis., PMID:29193305
Clinicopathologic and gene expression analysis of initial biopsies from patients with eosinophilic esophagitis refractory to therapy., PMID:28882697
Common Marker Genes Identified from Various Sample Types for Systemic Lupus Erythematosus., PMID:27257790
Eosinophil-Derived Neurotoxin (EDN/RNase 2) and the Mouse Eosinophil-Associated RNases (mEars): Expanding Roles in Promoting Host Defense., PMID:26184157
Safety of a New Amino Acid Formula in Infants Allergic to Cow's Milk and Intolerant to Hydrolysates., PMID:25844709
Transcriptome analysis of CD133-positive stem cells and prognostic value of survivin in colorectal cancer., PMID:25331798
Relationship between SNPs and expression level for candidate genes in rheumatoid arthritis., PMID:25221852
The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner., PMID:24738159
Elevation of Eosinophil-Derived Neurotoxin in Plasma of the Subjects with Aspirin-Exacerbated Respiratory Disease: A Possible Peripheral Blood Protein Biomarker., PMID:23805255
Genetic architecture of resilience of executive functioning., PMID:22711244
Elevated eosinophil protein X in urine from healthy neonates precedes development of atopy in the first 6 years of life., PMID:21680952
Effects of chronic ascariasis and trichuriasis on cytokine production and gene expression in human blood: a cross-sectional study., PMID:21666788
GATA transcription factors regulate the expression of the human eosinophil-derived neurotoxin (RNase 2) gene., PMID:19279013
Transcriptional regulation of human eosinophil RNase2 by the liver-enriched hepatocyte nuclear factor 4., PMID:19115260
siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts., PMID:16652140
Unique peptide identification of RNase A superfamily sequences based on reinforced merging algorithms., PMID:16568543
Effects of the very late adhesion molecule 4 antagonist WAY103 on human peripheral blood eosinophil vascular cell adhesion molecule 1-dependent functions., PMID:16210055
Blood cell gene expression profiling in rheumatoid arthritis. Discriminative genes and effect of rheumatoid factor., PMID:15158620
For research use only. Not for human or drug use.
