Catalog No.
RME82901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
Protein brahma homolog 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4, Protein BRG-1, Transcription activator BRG1, BRG1-associated factor 190A, SNF2-beta, SNF2L4, SMARCA4, ATP-dependent helicase SMARCA4, SNF2B, BRG1, BAF190A, Mitotic growth and transcription activator
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q3TKT4
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Y26
Arid1a-dependent canonical BAF complex suppresses inflammatory programs to drive efficient germinal center B cell responses., PMID:39143398
PD-1 antibody in combination with chemotherapy for the treatment of SMARCA4-deficient advanced undifferentiated carcinoma of the duodenum: Two case reports., PMID:38576599
Arid1a-dependent canonical BAF complex suppresses inflammatory programs to drive efficient Germinal Center B cell responses., PMID:38313292
Brain and Spinal Cord Tumors of Embryonic Origin., PMID:37452947
Unusual Aspects of Small Cell Carcinoma of the Ovary of Hypercalcaemic Type: Retained SMARCA4 Immunohistochemical Staining and Positive Staining With TLE1., PMID:37345679
Case report: Heterogenous SMARCA4-deficient thoracic non-small cell lung carcinoma with various responses to nivolumab., PMID:37051241
Characterization of Switch/Sucrose Nonfermenting Complex Proteins and Nestin Expression in a Cohort of Pediatric Central Nervous System Tumors., PMID:37036408
Malignant undifferentiated and rhabdoid tumors of the gastroesophageal junction and esophagus with SMARCA4 loss: a case series., PMID:36549598
Expanding the Use of an SS18-SSX Antibody for Molecular Assays in Synovial Sarcoma., PMID:35880992
Trans-activation of eotaxin-1 by Brg1 contributes to liver regeneration., PMID:35614068
Cytomorphologic features of SMARCA4-deficient non-small cell lung carcinoma and correlation with immunohistochemical and molecular features., PMID:35468657
Upregulation of Neogenin-1 by a CREB1-BAF47 Complex in Vascular Endothelial Cells is Implicated in Atherogenesis., PMID:35186922
Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation., PMID:34539636
Off-the-shelf proximity biotinylation for interaction proteomics., PMID:34408139
Small Cell Carcinoma of the Ovary, Hypercalcemic Type, in a 12-Month-Old Girl., PMID:34047234
Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation-Mass Spectrometry Assays., PMID:33771697
SMARCA4/BRG1-Deficient Non-Small Cell Lung Carcinomas: A Case Series and Review of the Literature., PMID:33367658
PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma., PMID:32358509
Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma., PMID:31906887
Hormonal aggressiveness according to the expression of cellular markers in corticotroph adenomas., PMID:30474823
An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm., PMID:29520069
Loss of Expression of a Novel Chromatin Remodeler SMARCA1 in Soft Tissue Sarcoma., PMID:31093468
Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition., PMID:28498870
Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein., PMID:27275536
The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth., PMID:25985234
Proteomics Differentiate Between Thyroid-Associated Orbitopathy and Dry Eye Syndrome., PMID:25829418
Differential SALL4 immunoexpression in malignant rhabdoid tumours and epithelioid sarcomas., PMID:24827994
Transcription of the Geminin gene is regulated by a negative-feedback loop., PMID:24554762
BRG1, a SWI/SNF chromatin remodeling enzyme ATPase, is required for maintenance of nuclear shape and integrity., PMID:24228137
An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells., PMID:24216762
A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1., PMID:23872584
The BRG1 chromatin remodeler regulates widespread changes in gene expression and cell proliferation during B cell activation., PMID:23757284
Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter., PMID:23571756
Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections., PMID:23405182
The clinical significance of SWI/SNF complex in pancreatic cancer., PMID:23229642
Differential chromatin structure encompassing replication origins in transformed and normal cells., PMID:23050047
Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle., PMID:21647563
Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression., PMID:21566516
Immunolocalization of BRG1-SWI/SNF protein during folliculogenesis in the porcine ovary., PMID:21492503
Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation., PMID:21245044
Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells., PMID:21102582
Production of a rat monoclonal antibody against Brg1., PMID:20025509
Histone marks and chromatin remodelers on the regulation of neurogenin1 gene in RA induced neuronal differentiation of P19 cells., PMID:19308998
The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone., PMID:19265191
Calcitonin, a regulator of the 25-hydroxyvitamin D3 1alpha-hydroxylase gene., PMID:19261615
Activity-dependent neuroprotective protein constitutes a novel element in the SWI/SNF chromatin remodeling complex., PMID:17878164
Expression of SRG3, a chromatin-remodelling factor, in the mouse oocyte and early preimplantation embryos., PMID:17462105
Two-component atomic force microscopy recognition imaging of complex samples., PMID:17196924
Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers., PMID:17075831
Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote., PMID:16880268
For research use only. Not for human or drug use.
