Catalog No.
RHE74503
Species reactivity
Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
GNAQ, GAQ, Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P50148
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1X96
A model workflow for microfluidic enrichment and genetic analysis of circulating melanoma cells., PMID:40316673
MAPK Signaling and Angiopoietin-2 Contribute to Endothelial Permeability in Capillary Malformations., PMID:40235979
Clinico-genomic features predict distinct metastatic phenotypes in cutaneous melanoma., PMID:39975034
The LINC01315-encoded small protein YAPer-ORF competes with PRP4k to hijack YAP signaling to aberrantly promote cell growth., PMID:39962243
Clinical benefit with tebentafusp in a patient with GNAQ mutant metastatic blue nevus-associated melanoma., PMID:39551602
Transcription repression of estrogen receptor alpha by ghrelin/Gq/11/YAP signaling in granulosa cells promotes polycystic ovary syndrome., PMID:39225978
A Phase I Study of the CDK4/6 Inhibitor Palbociclib in Combination with Cetuximab and Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma., PMID:37982827
A phase Ib trial of combined PKC and MEK inhibition with sotrastaurin and binimetinib in patients with metastatic uveal melanoma., PMID:37359242
Exonic variants in multiple myeloma patients associated with relapsed/ refractory and response to bortezomib regimens., PMID:35002457
Uveal Melanoma Metastasis., PMID:34830841
The WHO 2018 Classification of Cutaneous Melanocytic Neoplasms: Suggestions From Routine Practice., PMID:34277420
Nivolumab as adjuvant treatment for a spinal melanocytoma: A case report., PMID:34106633
Comprehensive molecular characterization of gastric cancer patients from phase II second-line ramucirumab plus paclitaxel therapy trial., PMID:33494793
CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites., PMID:33361125
Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas., PMID:31239162
[New molecular pathological strategies for malignant iris tumors]., PMID:30623224
Association of Somatic GNAQ Mutation With Capillary Malformations in a Case of Choroidal Hemangioma., PMID:30422215
Rates of ERBB2 Alterations across Melanoma Subtypes and a Complete Response to Trastuzumab Emtansine in an ERBB2-Amplified Acral Melanoma., PMID:30093446
Clinical Application of Circulating Tumor Cells and Circulating Tumor DNA in Uveal Melanoma., PMID:32913999
Requirement of Gαq/Gα11 Signaling in the Preservation of Mouse Intestinal Epithelial Homeostasis., PMID:28174748
Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma., PMID:28138035
Developments in targeted therapy in melanoma., PMID:27923592
Melanoma., PMID:27188223
Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ., PMID:23656586
Gαq gene promoter polymorphisms and rheumatoid arthritis in the Han Chinese population are not associated., PMID:23315865
Ocular melanoma: what's new?, PMID:22234256
G alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity., PMID:20624888
Gene-gene and gene-environment interactions on IgE production in prenatal stage., PMID:19968631
For research use only. Not for human or drug use.
