Catalog No.
RHE58203
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
Gamma-ECS, GCLC, Gamma-glutamylcysteine synthetase, GCS heavy chain, GLCLC, Glutamate--cysteine ligase catalytic subunit, GLCL
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P48506
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1X10
Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells., PMID:35379825
Probucol promotes high glucose-induced proliferation and inhibits apoptosis by reducing reactive oxygen species generation in Müller cells., PMID:31144240
The impact of ganglion cell layer cysts in diabetic macular oedema treated with anti-vascular endothelial growth factor., PMID:31099498
Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cells., PMID:28436007
Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress., PMID:27048381
TGFβ1 mediates alcohol-induced Nrf2 suppression in lung fibroblasts., PMID:25421510
Molecular cloning and analysis of Ancylostoma ceylanicum glutamate-cysteine ligase., PMID:25092620
Keap1 inhibition attenuates glomerulosclerosis., PMID:24523358
Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: the role of IL-6 signaling and Nrf2/AKR1C axis identification., PMID:23933386
Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy., PMID:23633659
Epidermal growth factor receptor transactivation is necessary for glucagon-like peptide-1 to protect PC12 cells from apoptosis., PMID:23147408
Molecular mechanisms of early growth response protein-1 (EGR-1) expression by quercetin in INS-1 beta-cells., PMID:22174042
The role of c-Jun phosphorylation in EpRE activation of phase II genes., PMID:19666106
Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1., PMID:18523133
Extract of Ginkgo biloba induces glutamate cysteine ligase catalytic subunit (GCLC)., PMID:18167050
Influence of glutathione-related genes on symptoms and immunologic markers among vulcanization workers in the southern Sweden rubber industries., PMID:18066575
Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels., PMID:17479437
[Effects of benzo(a)pyrene on the expression of gamma-glutamate-cysteine ligase: a primary study with rat alveolar epithelial cells]., PMID:17288842
4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes., PMID:17173895
Identification of an E-box motif as a transcriptional repressor element in the proximal promoter region of the GCLC gene in rat lung epithelial L2 cells., PMID:16198230
[Experimental study of E-box, a transcriptional suppressor element in gamma-GCS gene]., PMID:15949339
Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development., PMID:15336720
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase., PMID:11909699
Germinal center B cells lack homing receptors necessary for normal lymphocyte recirculation., PMID:6339668
For research use only. Not for human or drug use.
