Catalog No.
RHE39501
Species reactivity
Human, Mouse, Rat, Cow
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
PTGER2, PGE2 receptor EP2 subtype, Prostaglandin E2 receptor EP2 subtype, Prostanoid EP2 receptor, PGE receptor EP2 subtype
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P43116
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1W40
A novel angiogenesis-related scoring model predicts prognosis risk and treatment responsiveness in diffuse large B-cell lymphoma., PMID:37402040
The prostaglandin receptor EP2 determines prognosis in EP3-negative and galectin-3-high cervical cancer cases., PMID:31980713
Canine placental prostaglandin E2 synthase: expression, localization, and biological functions in providing substrates for prepartum PGF2alpha synthesis., PMID:25297547
Hormonal therapy deregulates prostaglandin-endoperoxidase synthase 2 (PTGS2) expression in endometriotic tissues., PMID:24423291
Autocrine and paracrine mechanisms of prostaglandin E₂ action on trophoblast/conceptus cells through the prostaglandin E₂ receptor (PTGER2) during implantation., PMID:23861370
PGE(2) receptor (EP(4)) agonists: potent dilators of human bronchi and future asthma therapy?, PMID:22244823
Prostaglandin E2 inhibits migration of colonic lamina propria fibroblasts., PMID:20803697
Prostaglandin receptors EP2 and IP are detectable in atherosclerotic arteries and plaques., PMID:20357748
Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells., PMID:19623651
Protection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2., PMID:19389932
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells., PMID:19116446
Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells., PMID:18319253
Expression of mRNAs encoding receptors that mediate stress signals in gonadotropin-releasing hormone neurons of the mouse., PMID:16721036
Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis., PMID:16446378
Postsynaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor., PMID:16251433
Immunolocalization of low-affinity prostaglandin E receptors, EP and EP, in adult human epidermis., PMID:15854037
Prostaglandin E2 receptor subtypes, EP1, EP2, EP3 and EP4 in human and mouse ocular tissues--a comparative immunohistochemical study., PMID:15380814
Activation of EP4 receptors contributes to prostaglandin E2-mediated stimulation of renal sensory nerves., PMID:15292051
Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling., PMID:15266025
E-prostanoid (EP)2/EP4 receptor-dependent maturation of human monocyte-derived dendritic cells and induction of helper T2 polarization., PMID:14872092
Disrupted function of tumor necrosis factor-alpha-stimulated gene 6 blocks cumulus cell-oocyte complex expansion., PMID:12959984
Loss of the EP2 prostaglandin E2 receptor in immortalized human keratinocytes results in increased invasiveness and decreased paxillin expression., PMID:12466123
Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues., PMID:11980863
Prostaglandin E(2) inhibits IL-18-induced ICAM-1 and B7.2 expression through EP2/EP4 receptors in human peripheral blood mononuclear cells., PMID:11970988
Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice., PMID:11809688
Detection of prostaglandin EP(1), EP(2), and FP receptor subtypes in human sclera., PMID:11726620
Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration., PMID:11093764
Prostanoid receptors in intestinal epithelium: selective expression, function, and change with inflammation., PMID:11049698
Upregulation of cyclooxygenase-1 and the PGE2 receptor EP2 in rat and human mesangioproliferative glomerulonephritis., PMID:10959556
Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3, and EP4 in human kidney., PMID:10477136
A conserved threonine in the second extracellular loop of the human EP2 and EP4 receptors is required for ligand binding., PMID:9788776
Prostaglandin receptors of the EP2 and EP4 subtypes regulate B lymphocyte activation and differentiation to IgE-secreting cells., PMID:9561124
For research use only. Not for human or drug use.
