Catalog No.
YHC44601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr105-Ile221
Predicted molecular weight
15.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09958
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FUR, PCSK3, PACE, FURIN, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, Furin
Furin-Triggered Peptide Self-Assembly Activates Coumarin Excimer Fluorescence for Precision Live-Cell Imaging., PMID:40509353
Immunogenicity of NSDV GP38 and the role of furin in GP38 proteolytic processing., PMID:40492757
The furin cleavage site is required for pathogenesis, but not transmission, of SARS-CoV-2., PMID:40492735
Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A., PMID:40485510
Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana., PMID:40483572
Pathological Glucose Levels Enhance Entry Factor Expression and Hepatic SARS-CoV-2 Infection., PMID:40442985
Repurposing of Furin Inhibitors to Reduce Pathogenic E. coli- and Shigella flexneri-Induced Cytotoxicity, Oxidative Stress and Inflammation in Mammalian Epithelial Cells., PMID:40426498
Unveiling the Modes of Action of a Recombinant Antimicrobial Peptide, Hepcidin (rGf-Hep), from Gerres filamentosus Against Pathogenic Vibrios: Membrane Disintegration and Reactive Oxygen Species Generation Leading to Cell Death., PMID:40423874
Is shorter the solution for tuberculosis treatment?, PMID:40414234
End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study., PMID:40408534
A Targeted Integration-Based CHO Cell Platform for Simultaneous Antibody Display and Secretion., PMID:40407690
Optimizing the pharmacokinetics and selectivity of TMPRSS2 inhibitors., PMID:40382841
Protein tyrosine phosphatase receptor type kappa (PTPRK) revisited: evolving insights into structure, function, and pathology., PMID:40355891
Virtual Screening of Phytoconstituents in Indian Spices Based on their Inhibitory Potential against SARS-CoV-2., PMID:40353411
SARS-CoV-2 Infection Reactivates HIV-1 Replication From Latency in U1 Cells., PMID:40349202
Immunogenicity evaluation of respiratory syncytial virus prefusogenic-F based virus-like-particles consisting of G and M proteins in mice., PMID:40334534
Inhibition of placental trophoblast fusion by guanylate-binding protein 5., PMID:40333975
Furin inhibits HSCs activation and ameliorates liver fibrosis by regulating PTEN-L/PINK1/parkin mediated mitophagy in mouse., PMID:40330431
Plasma proteomics identify novel biomarkers and dynamic patterns of biological aging., PMID:40328427
Identification of Endoplasmic Reticulum Stress-Related Genes in Acute Myocardial Infarction: A Bioinformatics Approach with Experimental Validation., PMID:40319218
Role of Angiotensin II in Venezuelan Equine Encephalitis: Narrative Review., PMID:40317791
Massive mutagenesis reveals an incomplete amyloid motif in Bri2 that turns amyloidogenic upon C-terminal extension., PMID:40314981
Melittin Inhibits Ovarian Cancer Cell Growth by Downregulating MMP9 Expression via the JAK2-STAT3 Signaling Pathway., PMID:40304331
Proteome-Wide Genetic Study in East Asians and Europeans Identified Multiple Therapeutic Targets for Ischemic Stroke., PMID:40304040
Comparative analysis of replication and immune evasion among SARS-CoV-2 subvariants BA.2.86, JN.1, KP.2, and KP.3., PMID:40298448
Genetic variants in TMPRSS2 influence SARS-CoV-2 infection susceptibility within Mexican Mestizos., PMID:40296872
Aligning Health Promotion Principles With Health Behavior Practice: Experiences With Qualitative Tuberculosis Research., PMID:40296570
An In-Depth Characterization of SARS-CoV-2 Omicron Lineages and Clinical Presentation in Adult Population Distinguished by Immune Status., PMID:40284983
The Roxadustat (FG-4592) ameliorates tubulointerstitial fibrosis by promoting intact FGF23 cleavage., PMID:40281613
RNA Sequencing Revealed Distinct Expression Profiles and Temporal Expression Dynamics in Murine Model of Foreign Body Reaction., PMID:40269512
Enhancing tuberculosis (TB) case detection among hospitalized patients through lay health worker led screening: a before-and-after study in KwaZulu-Natal, South Africa., PMID:40268977
Hepatoprotective and Antiatherosclerotic Effects of Oleoylethanolamide-Based Dietary Supplement in Dietary-Induced Obesity in Mice., PMID:40265441
Alterations in the Expression of Proprotein Convertase Genes in Human Esophagus Squamous Cell Carcinomas., PMID:40264581
Peptide-DNA conjugate-assisted DNA cyclization for highly efficient and sensitive detection of furin., PMID:40259668
Fighting tuberculosis hand in hand: A call to engage communities affected by TB as essential partners in research., PMID:40202965
Capture of fusion-intermediate conformations of SARS-CoV-2 spike requires receptor binding and cleavage at either the S1/S2 or S2' site., PMID:40198676
ACTG A5409 (RAD-TB): Study Protocol for a Phase 2 Randomized, Adaptive, Dose-Ranging, Open-Label Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis., PMID:40195983
Translational Insights into Cancer-Associated Fibroblast Infiltration-Related Biomarkers in Glioblastoma and Their Clinical Prognostic Value., PMID:40191237
The mammalian egg's zona pellucida, fertilization, and fertility., PMID:40180510
Prospective evaluation of 92 protein biomarkers for early detection of endometrial cancer., PMID:40177982
The furin cleavage site is required for pathogenesis, but not transmission of SARS-CoV-2., PMID:40161656
Cleaved vs. Uncleaved: How Furin Cleavage Reshapes the Conformational Landscape of SARS-CoV-2 Spike., PMID:40161653
Equitable access needed in clinical research., PMID:40146818
The Legacy of COVID-19 in Breast Milk: The Association of Elevated Anti-Inflammatory and Antimicrobial Proteins with Vaccination or Infection., PMID:40136436
Semaphorin 3E-Plexin D1 Axis Drives Lung Fibrosis through ErbB2-Mediated Fibroblast Activation., PMID:40112179
Consensus furin cleavage sites in the cuticular collagens DPY-17 and SQT-3 are required for Q neuroblast left-right asymmetric migration in Caenorhabditis elegans., PMID:40110475
Role of furin in the severity of COVID-19 infection via effects on miR-20b and miR-106a., PMID:40095093
SARS-CoV-2 Entry Factors ACE2 , TMPRSS2 and FURIN in Salivary Glands From Primary Sjögren's Disease., PMID:40091593
Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case-Control Study in the Department of Defense Serum Repository., PMID:40079721
Oral SARS-CoV-2 Infection and Risk for Long Covid., PMID:40074704
For research use only. Not for human or drug use.
