Catalog No.
RHE26601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Multicatalytic endopeptidase complex subunit MECl-1, MECL1, Macropain subunit MECl-1, Proteasome MECl-1, LMP10, PSMB10, Low molecular mass protein 10, Proteasome subunit beta-2i, Proteasome subunit beta type-10
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P40306
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1V71
HDACs alters negatively to the tumor immune microenvironment in gynecologic cancers., PMID:37572797
Can tonsillectomy modify the innate and adaptive immunity pathways involved in IgA nephropathy?, PMID:24756968
The immunoproteasome in steatohepatitis: its role in Mallory-Denk body formation., PMID:21256843
A novel role for the immunoproteasome in retinal function., PMID:20881299
Autoimmune reactivity against the 20S-proteasome includes immunosubunits LMP2 (beta1i), MECL1 (beta2i) and LMP7 (beta5i)., PMID:18375405
Development and characterization of human constitutive proteasome and immunoproteasome subunit-specific monoclonal antibodies., PMID:16101829
Antigen-processing machinery in human dendritic cells: up-regulation by maturation and down-regulation by tumor cells., PMID:15265880
IFN-alpha mediates the up-regulation of HLA class I on melanoma cells without switching proteasome to immunoproteasome., PMID:14645150
Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells., PMID:12407112
Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation., PMID:11717192
Tissue distribution of constitutive proteasomes, immunoproteasomes, and PA28 in rats., PMID:11032729
Interferon regulatory factor 1 mediates the interferon-gamma induction of the human immunoproteasome subunit multicatalytic endopeptidase complex-like 1., PMID:10575004
Invasion by Salmonella typhimurium induces increased expression of the LMP, MECL, and PA28 proteasome genes and changes in the peptide repertoire of HLA-B27., PMID:9746558
Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits., PMID:9311996
For research use only. Not for human or drug use.
