Catalog No.
RHE04302
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
CDC46, DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46, MCM5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P33992
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1U72
Advances in Cervical Cancer Diagnostics Based on Immunosensors: Innovative Approaches and Tumor Biomarkers., PMID:40192049
Label-free electrochemical immunosensor for picomolar detection of the cervical cancer biomarker MCM5., PMID:36038236
The Immunohistochemical Expression of MCM-3, -5, and -7 Proteins in the Uterine Fibroids., PMID:34449552
Proteomic analysis of host cellular proteins co-immunoprecipitated with duck enteritis virus gC., PMID:34091090
Comparison of TMA Technique and Routine Whole Slide Analysis in Evaluation of Proliferative Markers Expression in Laryngeal Squamous Cell Cancer., PMID:33144432
MCM5 urine expression (ADXBLADDER) is a reliable biomarker of high-risk non- muscle-invasive bladder cancer recurrence: A prospective matched case-control study., PMID:32924986
A Novel, non-invasive Test Enabling Bladder Cancer Detection in Urine Sediment of Patients Presenting with Haematuria-A Prospective Multicentre Performance Evaluation of ADXBLADDER., PMID:31307961
Diagnosis of urinary bladder urothelial carcinoma by immunocytology with p53, MCM5, MCM2 and Ki-67 antibodies using cell blocks derived from urine., PMID:30943322
Minichromosome Maintenance Proteins MCM-3, MCM-5, MCM-7, and Ki-67 as Proliferative Markers in Adrenocortical Tumors., PMID:30842144
Comparative Study of the Minichromosome Maintenance Proteins Complex (MCM 4/5/6) in Ameloblastoma and Unicystic Ameloblastoma., PMID:29845895
Significance of DNA Replication Licensing Proteins (MCM2, MCM5 and CDC6), p16 and p63 as Markers of Premalignant Lesions of the Uterine Cervix: Its Usefulness to Predict Malignant Potential., PMID:29373905
Effect of daidzein and equol on DNA replication in MCF-7 cells., PMID:29346578
Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology., PMID:28081547
Sox10 regulates skin melanocyte proliferation by activating the DNA replication licensing factor MCM5., PMID:27955842
A study of gene expression markers for predictive significance for bevacizumab benefit in patients with metastatic colon cancer: a translational research study of the Hellenic Cooperative Oncology Group (HeCOG)., PMID:24555920
Immunohistochemical features of multifocal melanoacanthoma in the hard palate: a case report., PMID:23356913
Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases., PMID:22556165
The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication., PMID:20663915
Improved screening for anal neoplasia by immunocytochemical detection of minichromosome maintenance proteins., PMID:18843031
Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress., PMID:18079179
Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase., PMID:17573775
Molecular architecture of the human GINS complex., PMID:17557111
p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer., PMID:15858126
DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process., PMID:15326181
DMBT1 expression is down-regulated in breast cancer., PMID:15301691
Diagnosis of oesophageal cancer by detection of minichromosome maintenance 5 protein in gastric aspirates., PMID:15266314
Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A., PMID:14749377
Diagnosis of genito-urinary tract cancer by detection of minichromosome maintenance 5 protein in urine sediments., PMID:12122098
Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa., PMID:11839717
Cdc6 expression as a marker of proliferative activity in brain tumors., PMID:11496317
DNA replication licensing and human cell proliferation., PMID:11493639
Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis., PMID:11046155
Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification., PMID:11024168
Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine., PMID:10551502
Minichromosome maintenance proteins as biological markers of dysplasia and malignancy., PMID:10473096
Improved cervical smear assessment using antibodies against proteins that regulate DNA replication., PMID:9843993
A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast., PMID:9366552
Cloning of Drosophila MCM homologs and analysis of their requirement during embryogenesis., PMID:9224901
Identification of two Xenopus laevis genes, xMCM2 and xCDC46, with sequence homology to MCM genes involved in DNA replication., PMID:8917078
Binding of human minichromosome maintenance proteins with histone H3., PMID:8798650
Fission yeast Nda1 and Nda4, MCM homologs required for DNA replication, are constitutive nuclear proteins., PMID:8838655
Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5., PMID:8751386
A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins., PMID:7601140
The association and involvement of some members of the P1 protein family in a cell-free DNA replication of Xenopus eggs., PMID:7733974
The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins., PMID:8265339
For research use only. Not for human or drug use.
