Catalog No.
RHE02501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
KNS, UKHC, KNS1, Conventional kinesin heavy chain, KIF5B, Ubiquitous kinesin heavy chain, Kinesin-1 heavy chain
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P33176
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1U65
Evolution of treatment strategies for solid tumors with RET rearrangement in China and real-world treatment status of Non-small Cell Lung Cancer (NSCLC)., PMID:39497173
Generation of recombinant and chickenized scFv versions of an anti-kinesin monoclonal antibody H2., PMID:37036074
Case report: Salvage capmatinib therapy in KIF5B-MET fusion-positive lung adenocarcinoma with resistance to telisotuzumab vedotin., PMID:36033470
Rab44 regulates murine mast cell-driven anaphylaxis through kinesin-1-dependent secretory granule translocation., PMID:35469841
Correlation of PD-L1 Expression with Clinicopathological and Genomic Features in Chinese Non-Small-Cell Lung Cancer., PMID:35444698
The genomic characteristics of RET fusion positive tumors in Chinese non-small cell lung cancer (NSCLC) patients., PMID:35220468
Immunolocalization of dynein, dynactin, and kinesin in the cerebral tissue as a possible supplemental diagnostic tool for traumatic brain injury in postmortem examination., PMID:31038188
Engagement of vimentin intermediate filaments in hypotonic stress., PMID:30887571
Kinesin-dependent transport of keratin filaments: a unified mechanism for intermediate filament transport., PMID:29944446
RET Fusion Lung Carcinoma: Response to Therapy and Clinical Features in a Case Series of 14 Patients., PMID:28082048
Custom Gene Capture and Next-Generation Sequencing to Resolve Discordant ALK Status by FISH and IHC in Lung Adenocarcinoma., PMID:27343444
A Unique Role for Endothelial Cell Kinesin Light Chain 1, Variant 1 in Leukocyte Transendothelial Migration., PMID:26994343
Identification of Kinesin-1 Cargos Using Fluorescence Microscopy., PMID:26966786
[New targets and new drugs in thoracic oncology]., PMID:26076869
Progress in Discovery of KIF5B-RET Kinase Inhibitors for the Treatment of Non-Small-Cell Lung Cancer., PMID:25625428
Diabetes induces changes in KIF1A, KIF5B and dynein distribution in the rat retina: implications for axonal transport., PMID:25064602
Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma., PMID:23932363
Usefulness of immunohistochemistry for the detection of the BRAF V600E mutation in Japanese lung adenocarcinoma., PMID:23927882
A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1., PMID:23872584
Diabetes alters KIF1A and KIF5B motor proteins in the hippocampus., PMID:23776493
A prospective PCR-based screening for the EML4-ALK oncogene in non-small cell lung cancer., PMID:22908099
Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex., PMID:22308290
Control of insulin granule dynamics by AMPK dependent KLC1 phosphorylation., PMID:21099273
Gadkin: A novel link between endosomal vesicles and microtubule tracks., PMID:20798811
Kinesin-1 regulates microtubule dynamics via a c-Jun N-terminal kinase-dependent mechanism., PMID:19759393
KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer., PMID:19383809
Kinesin-1 (uKHC/KIF5B) is required for bidirectional motility of ER exit sites and efficient ER-to-Golgi transport., PMID:18817524
Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells., PMID:17925227
Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver., PMID:17360972
GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin., PMID:15644324
Beta-dystrobrevin interacts directly with kinesin heavy chain in brain., PMID:14600269
Kinesin light-chain KLC3 expression in testis is restricted to spermatids., PMID:11319135
KIF5C, a novel neuronal kinesin enriched in motor neurons., PMID:10964943
For research use only. Not for human or drug use.
