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Anti-KDM5A Antibody (R1T69)

Catalog #:   RHD83401 Specific References (12) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, IP, WB
Accession: P29375
Overview

Catalog No.

RHD83401

Species reactivity

Human, Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

RBBP-2, RBBP2, JARID1A, [histone H3]-trimethyl-L-lysine(4) demethylase 5A, RBP2, KDM5A, Lysine-specific demethylase 5A, Histone demethylase JARID1A, Retinoblastoma-binding protein 2, Jumonji/ARID domain-containing protein 1A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P29375

Applications

FCM, IF, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1T69

Data Image
  • Western blot
    Western blot analysis of KDM5A / Jarid1A / RBBP2 expression in (1) HEK293 cell lysate; (2) Mouse spleen lysate.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
References

Assessing the Immune Cell Subset and Genetic Mutations in Patients With Palindromic Rheumatism Seronegative for Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide., PMID:35819819

The immune microenvironment features and response to immunotherapy in EBV-associated lymphoepithelioma-like cholangiocarcinoma., PMID:35780451

LncRNA IFITM4P promotes immune escape by up-regulating PD-L1 via dual mechanism in oral carcinogenesis., PMID:35051616

Exonic variants in multiple myeloma patients associated with relapsed/ refractory and response to bortezomib regimens., PMID:35002457

Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade., PMID:32908002

The therapeutic effect of dexmedetomidine on protection from renal failure via inhibiting KDM5A in lipopolysaccharide-induced sepsis of mice., PMID:31682847

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases., PMID:30538297

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development., PMID:24619213

Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4., PMID:21987186

Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms., PMID:21935404

Expression of the adhesion molecule CEACAM1 (CD66a, BGP, C-CAM) in breast cancer is associated with the expression of the tumor-suppressor genes Rb, Rb2, and p27., PMID:11964043

Retinoblastoma gene product-associated proteins in human colon cancer cell lines., PMID:8343169

Datasheet

Document Download

Anti-KDM5A Antibody (R1T69).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-KDM5A Antibody (R1T69) [RHD83401]
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