Catalog No.
RHD80601
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
HSD11, HSD11L, 11-beta-HSD1, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1, 11-beta-hydroxysteroid dehydrogenase 1, HSD11B1, SDR26C1, Short chain dehydrogenase/reductase family 26C member 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P28845
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1T62
Subclone from CT26 resistant to anti-PD-1 therapy associated with increased expression of genes related to glucocorticoids., PMID:38861853
Microbiota modulates the steroid response to acute immune stress in male mice., PMID:38361932
11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients., PMID:37943405
Local glucocorticoid synthesis regulates house dust mite-induced airway hypersensitivity in mice., PMID:37936704
Plasma proteomic profiling reveals KRT19 could be a potential biomarker in patients with anti-MDA5+ dermatomyositis., PMID:37160775
Utero-placental expression and functional implications of HSD11B1 and HSD11B2 in canine pregnancy†., PMID:36722005
Distinct blood protein profiles associated with the risk of short-term and mid/long-term clinical relapse in patients with Crohn's disease stopping infliximab: when the remission state hides different types of residual disease activity., PMID:36008101
The Gut Microbiota Affects Corticosterone Production in the Murine Small Intestine., PMID:33921780
The mediation of pigeon egg production by regulating the steroid hormone biosynthesis of pigeon ovarian granulosa cells., PMID:33142527
Neurotrophin-3 stimulates stem Leydig cell proliferation during regeneration in rats., PMID:33090725
Clinical outcome in anti-neutrophil cytoplasmic antibody-associated vasculitis and gene variants of 11β-hydroxysteroid dehydrogenase type 1 and the glucocorticoid receptor., PMID:30445609
Cortisol Homeostasis in the Epidermis is Influenced by Topical Corticosteroids in Patients with Atopic Dermatitis., PMID:28794569
Local Glucocorticoid Activation by 11β-Hydroxysteroid Dehydrogenase 1 in Keratinocytes: The Role in Hapten-Induced Dermatitis., PMID:27070821
Glucocorticoid metabolism in the bovine cumulus-oocyte complex matured in vitro., PMID:26519454
The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis., PMID:23391632
Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms in vascular endothelial cells., PMID:18573267
[Generation and characterization of monoclonal antibody against HSD11B1]., PMID:18177616
Human 11beta-hydroxysteroid dehydrogenase type 1 is enzymatically active in its nonglycosylated form., PMID:11027492
Human 11beta-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli., PMID:10781878
For research use only. Not for human or drug use.
