Catalog No.
YHC38401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe236-Thr398
Predicted molecular weight
20.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09086
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Oct-2, POU domain, class 2, transcription factor 2, OTF-2, OCT2, Octamer-binding protein 2, POU2F2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding transcription factor 2, OTF2
BCOR and ZC3H12A suppress a core stemness program in exhausted CD8+ T cells., PMID:40327039
Upregulation of PREX1 Expression by POU2F2 Promotes the Malignant Progression of Acute Myeloid Leukemia via the mTOR Pathway., PMID:40317800
Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2-Mediated Transcriptional Network in Multiple Myeloma., PMID:40167268
POU2F2+ B cells enhance antitumor immunity and predict better survival in non small cell lung cancer., PMID:39994401
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer's disease., PMID:39905093
POU2F2 activates the Akt/mTOR signalling pathway and enhances B lymphocyte function during diabetic kidney disease by promoting PIK3CD transcription., PMID:39401868
Expression of POU2F3 Transcription Factor and POU2AF2, POU2F3 Coactivator, in Tuft Cell-like Carcinoma and Other Tumors., PMID:39319626
LncRNA HOXA11-AS intercepts the POU2F2-mediated downregulation of SLC3A2 in osteoarthritis to suppress ferroptosis., PMID:39251054
Expression and Function of FAM72A Gene in Multiple MyelomaFAM72A., PMID:39129160
Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies., PMID:39029462
Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng., PMID:38821052
POU2F2-mediated upregulation of lncRNA PTPRG-AS1 inhibits ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis., PMID:38318853
Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury., PMID:38310257
IκBζ is a dual-use coactivator of NF-κB and POU transcription factors., PMID:38309274
A Systems Biology Approach for Investigating Significant Biomarkers and Drug Targets Common Among Patients with Gonorrhea, Chlamydia, and Prostate Cancer: A Pilot Study., PMID:38033384
Identification of genetic biomarkers, drug targets and agents for respiratory diseases utilising integrated bioinformatics approaches., PMID:37925496
SETD2 loss in renal epithelial cells drives epithelial-to-mesenchymal transition in a TGF-β-independent manner., PMID:37418588
CEBPB/POU2F2 modulates endothelin 1 expression in prehypertensive SHR vascular smooth muscle cells., PMID:36942826
The MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven cell proliferation by controlling the expression of OCT2., PMID:36849510
Multi-region sequencing depicts intratumor heterogeneity and clonal evolution in cervical cancer., PMID:36635412
Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution., PMID:36629404
TCDD alters essential transcriptional regulators of osteogenic differentiation in multipotent mesenchymal stem cells., PMID:36370075
POU Domain Class 2 Transcription Factor 2 Inhibits Ferroptosis in Cerebral Ischemia Reperfusion Injury by Activating Sestrin2., PMID:36306010
Identification of Key Non-coding RNAs and Transcription Factors in Calcific Aortic Valve Disease., PMID:35845040
Activation of MYO1G by lncRNA MNX1-AS1 Drives the Progression in Lung Cancer., PMID:35819746
SOX12 Promotes Thyroid Cancer Cell Proliferation and Invasion by Regulating the Expression of POU2F1 and POU3F1., PMID:35619584
Receptor for activated C kinase 1 promotes cervical cancer lymph node metastasis via the glycolysis‑dependent AKT/mTOR signaling., PMID:35616137
CBX7 represses the POU2F2 to inhibit the PD-L1 expression and regulate the immune response in bladder cancer., PMID:35526483
Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers., PMID:34461601
[Analysis of the functional role of polymorphism in the CDKN2B-AS1 gene GWAS-significant for primary open-angle glaucoma (an in-silico study)]., PMID:34410056
Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma epithelial cells., PMID:34176764
Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8., PMID:34010659
Long Non-Coding RNA ARAP1-AS1 Facilitates the Progression of Cervical Cancer by Regulating miR-149-3p and POU2F2., PMID:33965958
POU2F2 regulates glycolytic reprogramming and glioblastoma progression via PDPK1-dependent activation of PI3K/AKT/mTOR pathway., PMID:33931589
POU2F2 promotes the proliferation and motility of lung cancer cells by activating AGO1., PMID:33832481
OBF1 and Oct factors control the germinal center transcriptional program., PMID:33512466
Alterations to Placental Glucocorticoid Receptor Expression with Alcohol Consumption., PMID:33409870
A Network-Based Analysis Reveals the Mechanism Underlying Vitamin D in Suppressing Cytokine Storm and Virus in SARS-CoV-2 Infection., PMID:33362771
Increased expression of interleukin-21-inducible genes in minor salivary glands are associated with primary Sjögren's syndrome disease characteristics., PMID:33247940
The people behind the papers - Awais Javed and Michel Cayouette., PMID:32988973
Characterizing therapeutic signatures of transcription factors in cancer by incorporating profiles in compound treated cells., PMID:32886093
Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina., PMID:32878923
A Network-Based Bioinformatics Approach to Identify Molecular Biomarkers for Type 2 Diabetes that Are Linked to the Progression of Neurological Diseases., PMID:32041280
Overexpressing of POU2F2 accelerates fracture healing via regulating HMGA1/Wnt/β-catenin signaling pathway., PMID:31782345
Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord., PMID:31231191
Epigenetic Regulation of NAMPT by NAMPT-AS Drives Metastatic Progression in Triple-Negative Breast Cancer., PMID:30940661
Protein network analysis reveals selectively vulnerable regions and biological processes in FTD., PMID:30283816
Bioinformatics analysis of novel transcription factors and related differentially regulated modules in non-union skeletal fractures., PMID:29578472
Six2 is involved in GATA1-mediated cell apoptosis in mouse embryonic kidney-derived cell lines., PMID:28842839
Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network., PMID:28750683
For research use only. Not for human or drug use.
