Catalog No.
RHD55902
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
COX-1, Prostaglandin-endoperoxide synthase 1, PGH synthase 1, Prostaglandin H2 synthase 1, Cyclooxygenase-1, PHS 1, PTGS1, Prostaglandin G/H synthase 1, COX1, PGHS-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P23219
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1S26
COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells., PMID:33450390
Understanding the Interplay between COX-2 and hTERT in Colorectal Cancer Using a Multi-Omics Analysis., PMID:31614548
TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells., PMID:31555275
Effects of Cyclooxygenase on the Urothelium of the Urinary Bladder of Mice Exposed to Pelvic Radiation., PMID:27386631
The small tellurium-based compound SAS suppresses inflammation in human retinal pigment epithelium., PMID:27293373
The lack of aspirin resistance in patients with coronary artery disease., PMID:26980433
Expression of Prostaglandin E2 Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients., PMID:26225917
In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism., PMID:25238071
Adipose triglyceride lipase regulates eicosanoid production in activated human mast cells., PMID:25114172
MicroRNA-100-5p indirectly modulates the expression of Il6, Ptgs1/2 and Tlr4 mRNA in the mouse follicular dendritic cell-like cell line, FL-Y., PMID:24944008
Hormonal therapy deregulates prostaglandin-endoperoxidase synthase 2 (PTGS2) expression in endometriotic tissues., PMID:24423291
Type 2 lysophosphatidic acid receptor in gastric surface mucous cells: Possible implication of prostaglandin E2 production., PMID:24375908
Evaluation of laboratory methods routinely used to detect the effect of aspirin against new reference methods., PMID:24207016
Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway., PMID:24150174
Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results., PMID:23525414
New direct and indirect methods for the detection of cyclooxygenase 1 acetylation by aspirin; the lack of aspirin resistance among healthy individuals., PMID:23422285
Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process., PMID:23337807
How can we better classify NSAID hypersensitivity reactions?--validation from a large database., PMID:22739440
Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats., PMID:22233532
Cytosolic and calcium-independent phospholipase A(2) mediate glioma-enhanced proangiogenic activity of brain endothelial cells., PMID:21094175
Transient depletion of CD4(+) T cells augments IL-21-based immunotherapy of disseminated neuroblastoma in syngeneic mice., PMID:20039320
Cyclooxygenase-1 orchestrates germinal center formation and antibody class-switch via regulation of IL-17., PMID:19843949
Autoantibodies from schizophrenia patients induce cerebral cox-1/iNOS mRNA expression with NO/PGE2/MMP-3 production., PMID:19835666
Lunasin and lunasin-like peptides inhibit inflammation through suppression of NF-kappaB pathway in the macrophage., PMID:19682518
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease., PMID:19605646
Overexpression of progesterone receptor B increases sensitivity of human colon muscle cells to progesterone., PMID:18776045
Expression of Ca(2+)-independent and Ca(2+)-dependent phospholipases A(2) and cyclooxygenases in human melanocytes and malignant melanoma cell lines., PMID:18722548
Defective generation of a humoral immune response is associated with a reduced incidence and severity of collagen-induced arthritis in microsomal prostaglandin E synthase-1 null mice., PMID:18523303
FcepsilonRI- and Fcgamma receptor-mediated production of reactive oxygen species by mast cells is lipoxygenase- and cyclooxygenase-dependent and NADPH oxidase-independent., PMID:17982097
Anti-brain cholinergic auto antibodies from primary Sjögren syndrome sera modify simultaneously cerebral nitric oxide and prostaglandin biosynthesis., PMID:17920530
Expression of cyclooxygenase-1 and cyclooxygenase-2 in the normal human heart and in myocardial infarction., PMID:17868881
P2X7 receptor immunoreactive profile confined to resting and activated microglia in the epileptic brain., PMID:16635480
Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E2 production by microglia., PMID:16371234
Splenic PGE2-releasing macrophages regulate Th1 and Th2 immune responses in mice treated with heat-killed BCG., PMID:16204627
Proinflammatory cytokines and metalloproteases are expressed in the subacromial bursa in patients with rotator cuff disease., PMID:16171632
Cell-cell interaction underlies formation of fluid in the male reproductive tract of the rat., PMID:15851503
Cytokine expression and dendritic cell density in melanoma sentinel nodes., PMID:15846142
Activated human B lymphocytes express cyclooxygenase-2 and cyclooxygenase inhibitors attenuate antibody production., PMID:15728468
Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa., PMID:15720413
The 'alphabet' of rheumatoid arthritis treatment., PMID:15714747
Aspirin sensitivity: implications for patients with coronary artery disease., PMID:15613671
Nimesulide and indomethacin induce apoptosis in head and neck cancer cells., PMID:15482327
Elucidation of the mechanism of inhibition of cyclooxygenases by acyl-coenzyme A and acylglucuronic conjugates of ketoprofen., PMID:15476667
Molecular therapeutic targets in inflammation: cyclooxygenase and NF-kappaB., PMID:15379601
MITF is necessary for generation of prostaglandin D2 in mouse mast cells., PMID:15375155
Immunohistochemical localization of cyclooxygenase-1 and -2 in synovial tissues from patients with internal derangement or osteoarthritis of the temporomandibular joint., PMID:15337183
Species-specific expression of microsomal prostaglandin E synthase-1 and cyclooxygenases in male monkey reproductive organs., PMID:15301794
Paracrine upregulation of monocyte cyclooxygenase-2 by mediators produced by T lymphocytes: role of interleukin 17 and interferon-gamma., PMID:15229941
Upregulation of synoviocyte COX-2 through interactions with T lymphocytes: role of interleukin 17 and tumor necrosis factor-alpha., PMID:15229940
Cyclooxygenases 1, 2, and 3 and the production of prostaglandin I2: investigating the activities of acetaminophen and cyclooxygenase-2-selective inhibitors in rat tissues., PMID:15148345
For research use only. Not for human or drug use.
