Catalog No.
RHD49201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
Protein-glutamine deamidase TGM2, TGase II, Heart G alpha(h), Erythrocyte transglutaminase, Protein-glutamine gamma-glutamyltransferase 2, TG(C), Transglutaminase C, Protein-glutamine serotonyltransferase TGM2, tTG, tTgase, Transglutaminase-2, Protein-glutamine noradrenalinyltransferase TGM2, TGM2, TG2, TGase C, Protein G alpha(h), Protein-glutamine histaminyltransferase TGM2, Tissue transglutaminase, hhG alpha(h), G(h), hTG2, Transglutaminase H, Protein-glutamine dopaminyltransferase TGM2, TGC, Isopeptidase TGM2, TGase-2, TGase H, Transglutaminase II
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P21980
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1R92
Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis., PMID:40327404
Critical Role for Transglutaminase 2 in Scleroderma Skin Fibrosis and in the Development of Dermal Sclerosis in a Mouse Model of Scleroderma., PMID:39800950
Enhancing substrate specificity of microbial transglutaminase for precise nanobody labeling., PMID:39552758
A guide to selecting high-performing antibodies for Protein-glutamine gamma-glutamyltransferase 2 (TGM2) for use in western blot, immunoprecipitation and immunofluorescence., PMID:39220380
pH-Controlled Chemoselective Rapid Azo-Coupling Reaction (CRACR) Enables Global Profiling of Serotonylation Proteome in Cancer Cells., PMID:39208062
Bioorthogonal Labeling and Enrichment of Histone Monoaminylation Reveal Its Accumulation and Regulatory Function in Cancer Cell Chromatin., PMID:38848464
pH-Controlled chemoselective rapid azo-coupling reaction (CRACR) enables global profiling of serotonylation proteome in cancer cells., PMID:38766043
Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin., PMID:38562869
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease., PMID:38552723
Identification of inflammatory biomarkers in IgA nephropathy using the NanoString technology: a validation study in Caucasians., PMID:38291238
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis., PMID:37424036
Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease., PMID:37368893
Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines., PMID:37160910
Tissue transglutaminase activates integrin-linked kinase and β-catenin in ovarian cancer., PMID:35810788
Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack., PMID:35046049
Celiac Disease After Administration of Immune Checkpoint Inhibitors: A Case Report., PMID:34975913
Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition., PMID:33638284
The Role of Autophagy-Mediated Dengue Virus Antibody-Dependent Enhancement Infection of THP-1 Cells., PMID:33202415
Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease., PMID:33159915
Differentiating Staphylococcus infection-associated glomerulonephritis and primary IgA nephropathy: a mass spectrometry-based exploratory study., PMID:33057112
Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation., PMID:32793209
Dietary Gluten and Neurodegeneration: A Case for Preclinical Studies., PMID:32751379
Evaluation of Ocular Parameters in Adult Patients with Celiac Disease., PMID:32508197
HLA-DQ genotype and biochemical characterization of anti-transglutaminase 2 antibodies in patients with type 1 diabetes mellitus in Taiwan., PMID:32362042
Osteopontin contributes to late-onset asthma phenotypes in adult asthma patients., PMID:32009132
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2., PMID:31727780
Avoiding Small Intestinal Biopsies for Diagnosis of Celiac Disease in Children: A Reliable Strategy for All Patients?, PMID:29135820
Intestinal anti-transglutaminase 2 immunoglobulin A deposits in children at risk for coeliac disease (CD): data from the PreventCD study., PMID:29114847
Intestinal Production of Anti-Tissue Transglutaminase 2 Antibodies in Patients with Diagnosis Other Than Celiac Disease., PMID:28934109
No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease., PMID:27864127
Biochemical characterization of the medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2)., PMID:27855535
Immunohistochemical Expression of Antitissue Transglutaminase 2 in Tissue Injuries: An Interpretation Beyond Celiac Disease., PMID:27753658
Interpretation of serological tests in the diagnosis of celiac disease: Anti-deamidated gliadin peptide antibodies revisited., PMID:27452003
Recent Advances in Celiac Disease., PMID:27278238
Transglutaminase 2 May Be Associated with Peri-implant Gingival Overgrowth: Preliminary Assessments., PMID:26523722
Inflammation Mediated Metastasis: Immune Induced Epithelial-To-Mesenchymal Transition in Inflammatory Breast Cancer Cells., PMID:26207636
Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease., PMID:26001928
[Histological diagnosis and complications of celiac disease. Update according to the new S2k guidelines]., PMID:25820446
Diagnosing coeliac disease and the potential for serological markers., PMID:25266110
Upregulation of transglutaminase and ε (γ-glutamyl)-lysine in the Fisher-Lewis rat model of chronic allograft nephropathy., PMID:25143942
Celiac disease and autoimmunity., PMID:24979198
Intestinal titres of anti-tissue transglutaminase 2 antibodies correlate positively with mucosal damage degree and inversely with gluten-free diet duration in coeliac disease., PMID:24773630
Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators., PMID:24572070
High-titre circulating tissue transglutaminase-2 antibodies predict small bowel villous atrophy, but decision cut-off limits must be locally validated., PMID:24325651
Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes., PMID:24222690
TGM2 inhibition attenuates ID1 expression in CD44-high glioma-initiating cells., PMID:23877317
Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma., PMID:23765377
The role of TG2 in regulating S100A4-mediated mammary tumour cell migration., PMID:23469180
Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity., PMID:23425695
Intestinal anti-tissue transglutaminase antibodies in potential coeliac disease., PMID:23199325
For research use only. Not for human or drug use.
