Catalog No.
RHD46401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Tumor necrosis factor alpha-induced protein 3, TNFAIP3, OTU domain-containing protein 7C, TNF alpha-induced protein 3, Zinc finger protein A20, OTUD7C, Putative DNA-binding protein A20
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P21580
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1R79
Association of the TNFRSF1B-rs1061622 variant with nonresponse to infliximab in ulcerative colitis., PMID:40414945
Interim PET after 4 cycles predicts outcome in histomolecularly confirmed primary mediastinal B-cell lymphoma., PMID:40030008
Psoriasis harbors multiple pathogenic type 17 T-cell subsets: Selective modulation by risankizumab., PMID:39978685
A20 haploinsufficiency diagnosis beyond systemic lupus erythematosus: A systematic review of the literature., PMID:39672252
The Role of TNF Receptor-Associated Factor 5 in the Formation of Germinal Centers by B Cells During the Primary Phase of the Immune Response in Mice., PMID:39596396
TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases., PMID:39562788
Identification and experimental validation of genes associated with programmed cell death in dendritic cells of the thyroid tissue in Hashimoto's thyroiditis., PMID:39260305
Genetic polymorphisms to identify patients with an optimal response to tildrakizumab in psoriasis patients from real-life clinical practice., PMID:39081053
Prolonged xenokidney graft survival in sensitized NHP recipients by expression of multiple human transgenes in a triple knockout pig., PMID:38865482
Myeloid A20 is critical for alternative macrophage polarization and type-2 immune-mediated helminth resistance., PMID:38680500
Tumor necrosis factor alpha induced protein 3, interleukin 10, tumor necrosis factor alpha, and interleukin 17 F genes polymorphisms in Algerian patients with rheumatoid arthritis., PMID:38642181
Exploration of the shared gene signatures and biological mechanisms between ischemia-reperfusion injury and antibody-mediated rejection in renal transplantation., PMID:38266883
[A20 haploinsufficiency: what do clinicians need to know?]., PMID:38160098
Association between PYTPN22 rs2476601, VEGF rs833070, TNFAIP3 rs6920220 Polymorphisms and Risk for Rheumatoid Arthritis in Early Undifferentiated Arthritis Patients: A Pilot Study., PMID:37893542
Genomic associations with antibody response to an oral cholera vaccine., PMID:37699782
Efficacy and safety of zanubrutinib plus R-CHOP in treatment of non-GCB DLBCL with extranodal involvement., PMID:37671152
Comprehensive analysis of hub biomarkers associated with immune and oxidative stress in Hashimoto's thyroiditis., PMID:37543352
Clinical relevance of molecular aspects in extranodal marginal zone lymphoma: a critical appraisal., PMID:37389189
METTL14-Mediated m6A Modification of TNFAIP3 Involved in Inflammation in Patients With Active Rheumatoid Arthritis., PMID:37327357
Case Report: A novel mutation in TNFAIP3 in a patient with type 1 diabetes mellitus and haploinsufficiency of A20., PMID:37324276
Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies., PMID:36534518
High activation levels maintained in receptor-binding domain-specific memory B cells in people with severe coronavirus disease 2019., PMID:36353774
Do genetics contribute to TNF inhibitor response prediction in Psoriatic Arthritis?, PMID:36243888
New, potent, small molecule agonists of tyrosine kinase receptors attenuate dry eye disease., PMID:36091713
TNFAIP3 mutation causing haploinsufficiency of A20 with a hemophagocytic lymphohistiocytosis phenotype: a report of two cases., PMID:36064566
Myelin oligodendrocyte glycoprotein-associated disease is associated with BANK1, RNASET2 and TNIP1 polymorphisms., PMID:36054934
Three Chinese pedigrees of A20 haploinsufficiency: clinical, cytokine and molecular characterization., PMID:35958611
Study of clinical factors, focus score, lymphocyte type and NF-κB pathway in Sjögren's syndrome., PMID:35915313
STAT3 regulates inflammatory cytokine production downstream of TNFR1 by inducing expression of TNFAIP3/A20., PMID:35841281
The immune microenvironment features and response to immunotherapy in EBV-associated lymphoepithelioma-like cholangiocarcinoma., PMID:35780451
Genetic and Clinical Factors Associated with Olokizumab Treatment in Russian Patients with Rheumatoid Arthritis., PMID:35455757
The Biology of Ocular Adnexal Marginal Zone Lymphomas., PMID:35267569
Let-7a Targeting TNFAPI3 Promotes Vascular Endothelial Cell Apoptosis of Pediatric Patients with Henoch-Schönlein Purpura via NF-κB Signaling Pathway., PMID:35256897
Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage., PMID:35077396
Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction., PMID:34464884
Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management., PMID:34447369
Clinical characteristics and genetic analysis of A20 haploinsufficiency., PMID:34030699
Mutation analysis of the TNFAIP3 in A20 haploinsufficiency: A case report., PMID:34011076
Chronic hepatic involvement in the clinical spectrum of A20 haploinsufficiency., PMID:33966343
Casp8 acts through A20 to inhibit PD-L1 expression: The mechanism and its implication in immunotherapy., PMID:33934451
Potential of the tumor‑derived extracellular vesicles carrying the miR‑125b‑5p target TNFAIP3 in reducing the sensitivity of diffuse large B cell lymphoma to rituximab., PMID:33887878
Spectrum of Systemic Auto-Inflammatory Diseases in India: A Multi-Centric Experience., PMID:33815380
Connection of BANK1, Tolerance, Regulatory B cells, and Apoptosis: Perspectives of a Reductionist Investigation., PMID:33815360
What is the evidence that mycobacteria are associated with the pathogenesis of Sjogren's syndrome?, PMID:33665595
A20 regulates the therapeutic effect of anti-PD-1 immunotherapy in melanoma., PMID:33298620
COVID-19, varying genetic resistance to viral disease and immune tolerance checkpoints., PMID:33113212
Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL., PMID:32785655
DNGR1-Cre-mediated Deletion of Tnfaip3/A20 in Conventional Dendritic Cells Induces Pulmonary Hypertension in Mice., PMID:32755457
Targeted next-generation sequencing reveals molecular heterogeneity in non-chronic lymphocytic leukemia clonal B-cell lymphocytosis., PMID:32738175
Identification of TNFAIP3 as relapse biomarker and potential therapeutic target for MOG antibody associated diseases., PMID:32709905
For research use only. Not for human or drug use.
