Catalog No.
RHD35101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
APNH, NHE-1, Sodium/hydrogen exchanger 1, Solute carrier family 9 member 1, Na(+)/H(+) exchanger 1, APNH1, Na(+)/H(+) antiporter, amiloride-sensitive, SLC9A1, NHE1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P19634
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1R30
Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin- and empagliflozin-induced arterial relaxation., PMID:39056245
Reduced Nhe1 (Na+-H+ Exchanger-1) Function Protects ApoE-Deficient Mice From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysms., PMID:32475310
p38-MAP Kinase Negatively Regulates the Slow Force Response to Stretch in Rat Myocardium through the Up-Regulation of Dual Specificity Phosphatase 6 (DUSP6)., PMID:30816666
Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy., PMID:30262908
NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion., PMID:28098891
Endothelial Na+/H+ exchanger NHE1 participates in redox-sensitive leukocyte recruitment triggered by methylglyoxal., PMID:25270604
Defective maintenance of pH of stratum corneum is correlated with preferential emergence and exacerbation of atopic-dermatitis-like dermatitis in flaky-tail mice., PMID:24581509
pH sensing by FAK-His58 regulates focal adhesion remodeling., PMID:24043700
Sgk1-dependent stimulation of cardiac Na+/H+ exchanger Nhe1 by dexamethasone., PMID:23860121
Inhibition of carbonic anhydrase prevents the Na(+)/H(+) exchanger 1-dependent slow force response to rat myocardial stretch., PMID:23709596
Extracellular acidification activates cAMP responsive element binding protein via Na+/H+ exchanger isoform 1-mediated Ca²⁺ oscillation in central nervous system pericytes., PMID:22922957
JAK2 mediates the acute response to decreased cell volume in mouse preimplantation embryos by activating NHE1., PMID:22740348
Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains., PMID:21797866
[Inhibition of NHE1 promotes hypoxia-induced differentiation of K562 leukemic cells]., PMID:21729545
High capacity Na+/H+ exchange activity in mineralizing osteoblasts., PMID:21413028
Role of Na+/H+ exchanger in resveratrol-induced growth inhibition of human breast cancer cells., PMID:21191669
The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors., PMID:19622752
5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes., PMID:18187546
Role of epidermal growth factor receptor (EGFR)-signaling versus cellular acidosis via Na+/H+ exchanger1(NHE1)-inhibition in troglitazone-induced growth arrest of breast cancer-derived cells MCF-7., PMID:17982257
Effect of chronic elevated carbon dioxide on the expression of acid-base transporters in the neonatal and adult mouse., PMID:17652362
Signal transduction mechanisms involved in the proliferation of C6 glioma cells induced by lysophosphatidic acid., PMID:16176063
Involvement of the Na+-independent Cl-/HCO3- exchange (AE) isoform in the compensation of myocardial Na+/H+ isoform 1 hyperactivity in spontaneously hypertensive rats., PMID:15897921
Renal expression of novel Na+/H+ exchanger isoform NHE8., PMID:12409279
For research use only. Not for human or drug use.
