Catalog No.
RHD11002
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
FOSL2, Fos-related antigen 2, FRA-2, FRA2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15408
Applications
FCM, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1P76
Pulmonary vascular remodeling in Fra-2 transgenic mice is driven by type 2 inflammation and accompanied by pulmonary vascular hyperresponsiveness., PMID:39903186
The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma., PMID:34076685
FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts., PMID:33754039
Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10., PMID:32220948
Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis., PMID:28805015
Unifying mechanism for different fibrotic diseases., PMID:28424250
Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma., PMID:27864286
OX40L blockade protects against inflammation-driven fibrosis., PMID:27298374
Histone Demethylation and Toll-like Receptor 8-Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-2., PMID:26814616
miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation., PMID:25367574
FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells., PMID:24587342
Transcriptional regulation of the human bone sialoprotein gene by fibroblast growth factor 2., PMID:23485603
Effects of intermittent hypoxia on leptin signalling in the carotid body., PMID:23201827
CD40 activation induces NREM sleep and modulates genes associated with sleep homeostasis., PMID:23072727
Transcriptional regulation of the mouse CD11c promoter by AP-1 complex with JunD and Fra2 in dendritic cells., PMID:22990073
Histone modifications on the adrenergic induction of type II deiodinase in rat pinealocytes., PMID:21704117
Endothelin-1 regulates rat bone sialoprotein gene transcription., PMID:20587945
The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis., PMID:20039427
Fos- and Jun-related transcription factors are involved in the signal transduction pathway of mechanical loading in condylar chondrocytes., PMID:16373449
Induction of AP-1 activity by androgen activation of the androgen receptor in LNCaP human prostate carcinoma cells., PMID:15486991
Fos-related antigen 2 controls protein kinase A-induced CCAAT/enhancer-binding protein beta expression in osteoblasts., PMID:15299028
The genetic modifier Rpe65Leu(450): effect on light damage susceptibility in c-Fos-deficient mice., PMID:12766089
Effect of exercise on mRNA expression of select adrenal medullary catecholamine biosynthetic enzymes., PMID:12133851
Composition and function of AP-1 transcription complexes during muscle cell differentiation., PMID:11877423
The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene., PMID:11861672
Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D., PMID:11254751
Differential expression and phosphorylation of particular fos family members by kainate in nuclear and cytosolic fractions of murine hippocampus., PMID:11098108
Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol)., PMID:10662601
Enterocyte-like differentiation of the Caco-2 intestinal cell line is associated with increases in AP-1 protein binding., PMID:10027748
The effects of measles virus persistent infection on AP-1 transcription factor binding in neuroblastoma cells., PMID:9237627
Changes in the expression of transcription factors ATF-2 and Fra-2 after axotomy and during regeneration in rat retinal ganglion cells., PMID:8883934
Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site., PMID:8612540
Hormonal modulation of major histocompatibility complex class I gene expression involves an enhancer A-binding complex consisting of Fra-2 and the p50 subunit of NF-kappa B., PMID:7744783
For research use only. Not for human or drug use.
