Catalog No.
YHC33801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly1441-Ala1669
Predicted molecular weight
26.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08572
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COL4A2, Collagen alpha-2(IV) chain
Blood biochemical landscape and new insights into clinical decision-making for polycystic ovary syndrome in Chinese women: a prospective cohort study., PMID:40375948
Investigation of the Pathogenesis of Liver Fibrosis Associated with Type 2 Diabetes Mellitus via Bioinformatic Analysis., PMID:40299397
A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome., PMID:40279671
Host transcriptome response to Mycoplasma bovis and bovine viral diarrhea virus in bovine tissues., PMID:40211134
Exome sequencing of a Portuguese cohort of early-onset Alzheimer's disease implicates the X-linked lysosomal gene GLA., PMID:40185916
Acute exposure to antimony elicits endocrine disturbances, leading to PCOS and ovarian fibrosis in female zebrafish., PMID:40174734
Identification of Ferroptosis- and Hypoxia-related Genes in iPSC-derived Oligodendrocyte Precursor Cells from Multiple Sclerosis Patients., PMID:40127044
Integrative analysis of semaphorins family genes in colorectal cancer: implications for prognosis and immunotherapy., PMID:40103807
Phenotype and surgical management of drug-resistant epilepsy in patients with COL4A1 and COL4A2 variants., PMID:40055992
Complement C5a and C5a receptor 1 mediates glomerular damage in focal segmental glomerulosclerosis., PMID:39984108
Integrative Proteomics and Phosphoproteomics Profiling of Symptomatic Accessory Navicular Bone Based on Tandem Mass Tag Technology., PMID:39698044
COL4A2 -Related Disorder Presenting in Adulthood With Rhabdomyolysis., PMID:39679724
An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis., PMID:39656438
Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites., PMID:39580674
Multiple intracerebral hematomas during SEEG recording and intradural hemorrhage after spinal tap: A case report prompting more research on collagen IV gene mutation and oral nicotine consumption as risk factors., PMID:39579033
Integrative transcriptome analysis reveals Serpine2 promotes glomerular mesangial cell proliferation and extracellular matrix accumulation via activating ERK1/2 signalling pathway in diabetic nephropathy., PMID:39557806
Podoplanin Expression in Early-Stage Colorectal Cancer-Associated Fibroblasts and Its Utility as a Diagnostic Marker for Colorectal Lesions., PMID:39451200
Alterations in the placental proteome in association with the presence of black carbon particles: A discovery study., PMID:39442658
IL6 and WNK2 polymorphisms and prognosis in patients with intracerebral hemorrhage receiving edaravone., PMID:39433142
ASSESSMENT OF RETINAL ARTERIOLAR TORTUOSITY IN PATIENTS WITH COL4A1 OR COL4A2 MUTATIONS., PMID:39405554
Changes of collagen content in lung tissues of plateau yak and its mechanism of adaptation to hypoxia., PMID:39372716
Identification of a novel intronic variant in COL4A2 gene associated with fetal severe cerebral encephalomalacia and subdural hemorrhage., PMID:39350129
Identification of Genetic Loci Associated With Intracerebral Hemorrhage Using a Multitrait Analysis Approach., PMID:39298701
COL4A2 enhances thyroid cancer cell proliferation through the AKT pathway., PMID:39220121
Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage., PMID:39216230
Teaching NeuroImage: Porencephaly and Hemorrhage in Infantile COL4A2-Related Cerebral Microangiopathy., PMID:39116375
Skeletal pathology in mouse models of Gould syndrome is partially alleviated by genetically reducing TGFβ signaling., PMID:39097038
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
Multiorgan manifestations of COL4A1 and COL4A2 variants and proposal for a clinical management protocol., PMID:39016117
Col4a2 Mutations Contribute to Infantile Epileptic Spasm Syndrome and Neuroinflammation., PMID:39006838
Comprehensive analysis of the expression, prognostic, and immune infiltration for COL4s in stomach adenocarcinoma., PMID:38907304
Identification of established and novel extracellular matrix components in glioblastoma as targets for angiogenesis and prognosis., PMID:38775886
Evaluating neural crest cell migration in a Col4a1 mutant mouse model of ocular anterior segment dysgenesis., PMID:38729574
Identification of potential candidate genes for the Huoyan trait in developing Wulong goose embryos by transcriptomic analysis., PMID:38727584
AP-1-dependent fibrosis: Exploring its potential role in the pathogenesis of placental transmogrification of the lung (PTL) via tissue-level transcriptome analysis., PMID:38718468
TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage., PMID:38717426
Bioinformatics analysis revealed the potential crosstalk genes and molecular mechanisms between intracranial aneurysms and periodontitis., PMID:38685029
Collagen IV assembly is influenced by fluid flow in kidney cell-derived matrices., PMID:38670459
Association of the COL4A2 Gene Polymorphisms with Primary Intracerebral Hemorrhage Risk and Outcome in Chinese Han Population., PMID:38565785
Aerobic Exercise Modulates Proteomic Profiles in Gastrocnemius Muscle of db/db Mice, Ameliorating Sarcopenia., PMID:38541736
Sex-specific genetic architecture of blood pressure., PMID:38459180
Infantile hemiparesis and porencephaly due to a COL4A1 mutation: Gould syndrome., PMID:38355202
Cerebrospinal fluid proteomic signatures are associated with symptom severity of first-episode psychosis., PMID:38340697
The anoikis-related gene signature predicts survival and correlates with immune infiltration in osteosarcoma., PMID:38217543
Notch signaling pathway induces expression of type IV collagen in angiogenesis., PMID:38167713
Variants in exon 2 of MED12 gene causes uterine leiomyoma's through over-expression of MMP-9 of ECM pathway., PMID:38041927
Extracellular matrix analysis of fibrosis: A step towards tissue engineering for urethral stricture disease., PMID:38032942
Identification and Validation of CXCL2 as a Key Gene for Childhood Obesity., PMID:38010448
Effects of Doxorubicin on Extracellular Matrix Regulation in Primary Cardiac Fibroblasts from Mice., PMID:37974221
Impaired intracellular Ca2+ signaling contributes to age-related cerebral small vessel disease in Col4a1 mutant mice., PMID:37963192
For research use only. Not for human or drug use.
