Catalog No.
YHC33301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala678-Leu894
Predicted molecular weight
26.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08514
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb
Generation of integration-free induced pluripotent stem cell (iPSC) line MURAi002-A from hemoglobin E/β-thalassemia disease patient harboring βE/β0 (CD41/42, -CTTT) compound heterozygous mutation., PMID:40441082
The Effects of Plasma Exosomes of Young Individuals Compared to Old Ones on Age-Related Inflammation and Lineage Differentiation of CD34+ Umbilical Cord Blood Hematopoietic Stem Cells., PMID:40325533
Block of Kv1 potassium channels and NMR structure of recombinant conotoxin κ-SrXIA., PMID:40324600
The Reactive Oxygen Species Scavenger N-Acetyl-L-Cysteine Reduces Storage-Dependent Decline in Integrin α IIb β 3-Mediated Platelet Function, Inhibiting Pre-Activation of Integrin and Its β 3 Subunit Cleavage., PMID:40321407
Glanzmann thrombasthenia: a multi-center study of demographics, clinical spectrum, and treatment efficacy., PMID:40301132
Unbiased analysis of NUP98-KDM5A-induced murine leukemia reveals phenotypic heterogeneity recapitulating human disease subtypes., PMID:40258564
Novel homozygous frameshift mutation of ITGB3 in the Glanzmann thrombasthenia patient with abnormal bone metabolism and congenital bone defects., PMID:40251671
Regulation of in vitro human hematopoietic differentiation by dioxin-like compounds., PMID:40187479
Association between extracellular vesicles (EVs) and thrombosis in antiphospholipid syndrome., PMID:40123163
Platelet glycoprotein VI promotes folic acid-induced acute kidney injury through interaction with tubular epithelial cell-derived galectin-3., PMID:40119472
Lienal Polypeptide Decreases Immune Thrombocytopenia in a Mouse Model by Upregulating Cytokine Production and Increasing the Levels of CD4+, CD8+, and T Regulatory Cells., PMID:40113259
Multimodal discovery of bavachinin A: A natural FLT3 agonist for treating thrombocytopenia., PMID:40058315
Analysis of thalassemia genotypes and HbA2 test results in pregnant women in Shenzhen, China., PMID:40033000
[Hematological Characteristics of Neonates with Abnormal Hemoglobin and Their Parents in Guangzhou Area]., PMID:40017204
Oxymatrine, a novel TLR2 agonist, promotes megakaryopoiesis and thrombopoiesis through the STING/NF-κB pathway., PMID:39906691
ADAMTS13 Improves Endothelial Function and Reduces Inflammation in Diabetic Retinopathy., PMID:39851513
Nootkatone Derivative Nootkatone-(E)-2-iodobenzoyl hydrazone Promotes Megakaryocytic Differentiation in Erythroleukemia by Targeting JAK2 and Enhancing JAK2/STAT3 and PKCδ/MAPK Crosstalk., PMID:39791711
Modeling the Impact of Extracellular Vesicle Cargoes in the Diagnosis of Coronary Artery Disease., PMID:39767589
Dengue infection changes the expressions of CD154 and CD148 in human platelets., PMID:39710119
Exosomal miR-146a-5p derived from bone marrow mesenchymal stromal cells regulate Th1/Th2 balance and alleviates immune thrombocytopenia in pregnancy., PMID:39699695
Unravelling the ontogeny and tissue-specific expression profiles of immune-related genes in the near-threatened endemic catfish, Clarias dussumieri., PMID:39642945
Molecular cloning, expression analysis, and functional characterization of an interleukin-15 like gene in common carp (Cyprinus carpio L.)., PMID:39628491
Influence of exposure duration on human pressure-induced inflammatory responses: Comparison between tunnel workers and underwater divers., PMID:39567182
Compound K Promotes Megakaryocytic Differentiation by NLRP3 Inflammasome Activation., PMID:39456190
Engineering Hyperechogenic Colloids with Clot-Targeting Capabilities from Platelet-Derived Membranes., PMID:39360874
Oxazolidinone antibiotics impair ex vivo megakaryocyte differentiation from hematopoietic progenitor cells and their maturation into platelets., PMID:39297641
Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation., PMID:39304946
Genetic Profile of Beta-Thalassemia and Sickle Cell Disease in Eastern Uttar Pradesh., PMID:39267277
[Platelet-specific Rictor knockout inhibits platelet production and activation and reduces thrombosis in mice]., PMID:39276057
Modulation of Staphylococcus aureus gene expression during proliferation in platelet concentrates with focus on virulence and platelet functionality., PMID:39052660
Trauma patients have reduced ex vivo flow-dependent platelet hemostatic capacity in a microfluidic model of vessel injury., PMID:38985805
[Pedigree Analysis and Molecular Mechanism Study of Hereditary Glanzmann Thrombasthenia Caused by Compound Heterozygous Mutation of the ITGA2B Gene]., PMID:38951065
[Analysis of the Gene Mutation Type and Frequency of Thalassemia Patients in Jingzhou Area]., PMID:38926976
[Thalassemia Genotypes and HbA2 levels of Children in Wuzhou, Guangxi]., PMID:38926975
Xuefu Zhuyu decoction alleviates deep vein thrombosis through inhibiting the activation of platelets and neutrophils via sirtuin 1/nuclear factor kappa-B pathway., PMID:38908490
The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors., PMID:38853593
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia., PMID:38845541
Off-target effect of high-dose sildenafil on adenosine 5'- diphosphate and collagen-induced platelet activation through mitogen-activated protein kinase pathway in treated BALB/C mice and in vitro experiments: A preliminary study., PMID:38808925
Identification and functional analyses of CD4-1+ cells in grass carp (Ctenopharyngodon idella)., PMID:38797336
SDF-1 promotes metastasis of NSCLC by enhancing chemoattraction of megakaryocytes through the PI3K/Akt signaling pathway., PMID:38726826
An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections., PMID:38718314
Decreasing circ_0014614 promotes the differentiation of bone marrow flineage cells into megakaryocytes in essential thrombocythemia via activiation of miR-138-5p/caspase3 axis., PMID:38703475
Improving platelet function following prophylactic platelet transfusion in patients with hematological malignancies., PMID:38682289
[Effects of Platelet-Rich Plasma-Derived Exosomes on Proliferation and Migration of Tendon Stem/Progenitor Cell]., PMID:38548389
Inducible IL-2 production and IL-2+ cell expansion are landmark events for T-cell activation of teleost., PMID:38499218
Adjuvant effects of β-defensin on DNA vaccine OmpC against edwardsiellosis in flounder (Paralichthys olivaceus)., PMID:38471627
A New δ-Globin Gene Variant: Hb A2-Yulin [δ46(CD5)Gly→Arg,HBD: C.139G > A]., PMID:38450437
Extracellular vesicles are a late marker of inflammation, hypercoagulability and COVID-19 severity., PMID:38341321
Platelet Proteome Reveals Novel Targets for Hypercoagulation in Pseudoexfoliation Syndrome., PMID:38338682
Spatiotemporal expression profiles of c-Mpl mRNA in the tooth germ: Comparative expression dynamics of vascularization-related genes., PMID:38336176
For research use only. Not for human or drug use.
