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Anti-CLU/Clusterin Antibody (R1N16)

Catalog #:   RMC84101 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IP, WB
Accession: Q06890
Overview

Catalog No.

RMC84101

Species reactivity

Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IP: 1:20, WB: 1:500-1:1000

Target

APOJ, ApoJalpha, NA1/NA2, Complement cytolysis inhibitor, Complement cytolysis inhibitor a chain, Ku70-binding protein 1, Testosterone-repressed prostate message 2, ApoJbeta, TRPM-2, Complement cytolysis inhibitor b chain, SGP-2, KUB1, Apolipoprotein J, Apo-J, Clusterin, Sulfated glycoprotein 2, Aging-associated gene 4 protein, CLI, CLU, Complement-associated protein SP-40,40

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q06890

Applications

IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1N16

Data Image
  • Western blot
    Western blot analysis of Clusterin alpha chain in rat Brain lysates using Clusterin alpha Chain antibody.
References

Tracking clusterin expression in hematopoietic stem cells reveals their heterogeneous composition across the lifespan., PMID:40132120

The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome., PMID:39859144

Targeting immune checkpoints on myeloid cells: current status and future directions., PMID:39751898

A non-invasive model for diagnosis of primary Sjogren's disease based on salivary biomarkers, serum autoantibodies, and Schirmer's test., PMID:39695856

Complement C7 and clusterin form a complex in circulation., PMID:38333209

First Data on Ornithodoros moubata Aquaporins: Structural, Phylogenetic and Immunogenic Characterisation as Vaccine Targets., PMID:35745548

A comprehensive molecular approach in fish allergy: Usefulness in daily clinical practice., PMID:35716706

Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development., PMID:35628842

Potential participation of CTRP6, a complement regulator, in the pathology of age related macular degeneration., PMID:35397057

Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms., PMID:35062233

Changes in Expression of Specific mRNA Transcripts after Single- or Re-Irradiation in Mouse Testes., PMID:35052491

Genomics of Alzheimer's disease implicates the innate and adaptive immune systems., PMID:34708251

Serum Clusterin Level Could Reflect the Current Activity of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis., PMID:34672135

Clusterin enhances cell survival by suppressing neuronal nitric-oxide synthase expression in the rhodopsin S334ter-line3 retinitis pigmentosa model., PMID:34242654

The Anti-HER3 mAb Seribantumab Effectively Inhibits Growth of Patient-Derived and Isogenic Cell Line and Xenograft Models with Oncogenic NRG1 Fusions., PMID:33824166

Discovery and validation of FBLN1 and ANT3 as potential biomarkers for early detection of cervical cancer., PMID:33602229

Clusterin Deficiency Predisposes C57BL/6j Mice to Cationic Bovine Serum Albumin-Induced Glomerular Inflammation., PMID:33262633

Chronic treatment with the (iso-)glutaminyl cyclase inhibitor PQ529 is a novel and effective approach for glomerulonephritis in chronic kidney disease., PMID:33159802

Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells., PMID:32597148

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease., PMID:32296418

Colorimetric Paper-Based Immunosensor for Simultaneous Determination of Fetuin B and Clusterin toward Early Alzheimer's Diagnosis., PMID:31661258

Differential effects of apoE and apoJ mimetic peptides on the action of an anti-Aβ scFv in 3xTg-AD mice., PMID:30026023

Development of a Label-Free Immunosensor for Clusterin Detection as an Alzheimer's Biomarker., PMID:29361679

Expression of clusterin in colorectal carcinoma in relation to clinicopathological criteria., PMID:29279586

Inhibiting the Ca2+ Influx Induced by Human CSF., PMID:29241555

Effects of an Aβ-antibody fragment on Aβ aggregation and astrocytic uptake are modulated by apolipoprotein E and J mimetic peptides., PMID:29155887

Downregulation of Apolipoprotein-E and Apolipoprotein-J in Moyamoya Disease-A Proteome Analysis of Cerebrospinal Fluid., PMID:28843803

Spatiotemporal expression patterns of clusterin in the mouse inner ear., PMID:28687930

A Preliminary Study: PS1 Increases U1 snRNA Expression Associated with AD., PMID:28577205

Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells., PMID:28076321

Toll-like receptor 4 signaling is required for clusterin-induced tumor necrosis factor-α secretion in macrophage., PMID:27965092

The emerging roles of clusterin on reduction of both blood retina barrier breakdown and neural retina damage in diabetic retinopathy., PMID:27232509

Serum Clusterin as a Prognostic Marker of Chronic Spontaneous Urticaria., PMID:27175709

Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses., PMID:27148688

Clusterin Binds to Aβ1-42 Oligomers with High Affinity and Interferes with Peptide Aggregation by Inhibiting Primary and Secondary Nucleation., PMID:26884339

Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis., PMID:26399194

Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases., PMID:25940137

Evaluation of vaccine seroresponse rates and adverse event rates through Bayesian and frequentist methods., PMID:25909683

Role of an extracellular chaperone, Clusterin in the pathogenesis of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma., PMID:25057782

Clusterin expression in gastrointestinal neuroendocrine tumours is highly correlated with location and is helpful in determining the origin of liver metastases., PMID:24807631

A multimarker panel for circulating tumor cells detection predicts patient outcome and therapy response in metastatic colorectal cancer., PMID:24752533

Diagnostic evaluation of urinary angiogenin (ANG) and clusterin (CLU) as biomarker for bladder cancer., PMID:24696417

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer., PMID:24512919

Syndecan-1 knockdown in endometrial epithelial cells alters their apoptotic protein profile and enhances the inducibility of apoptosis., PMID:24478463

Far-infrared radiation inhibits proliferation, migration, and angiogenesis of human umbilical vein endothelial cells by suppressing secretory clusterin levels., PMID:24334140

Quantification of clusterin in paired cerebrospinal fluid and plasma samples., PMID:24146185

Plasma clusterin concentrations may predict resistance to intravenous immunoglobulin in patients with Kawasaki disease., PMID:23956692

Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction., PMID:23454623

Protective role of clusterin in preserving endothelial function in AL amyloidosis., PMID:22981431

Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma., PMID:22718493

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-CLU/Clusterin Antibody (R1N16) [RMC84101]
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