Catalog No.
RHC81101
Species reactivity
Human, Rat, Hamster
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Osteopontin, BNSP, Uropontin, OPN, SPP-1, Secreted phosphoprotein 1, Bone sialoprotein 1, Nephropontin, Urinary stone protein, SPP1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P10451
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1M67
An electrochemically charged nanoengineered bioelectronic immunosensing device for osteopontin detection in serum samples., PMID:40405794
A serum biomarker panel and miniarray detection system for tracking disease activity and flare risk in lupus nephritis., PMID:40375995
TSAb inhibits osteogenic differentiation of MC3T3-E1 cells and exacerbates bone loss in Graves' disease mice., PMID:40354515
Osteopontin in Chronic Inflammatory Diseases: Mechanisms, Biomarker Potential, and Therapeutic Strategies., PMID:40282293
Hyaluronic acid-based hydrogel microspheres with multi-responsive properties for antibacterial therapy and bone regeneration in Staphylococcus aureus-infected skull defects., PMID:40236808
Osteopontin inhibits autophagy via CD44 and avβ3 integrin and promotes cell proliferation in osteoarthritic fibroblast-like synoviocytes., PMID:40102843
Bisphenols exposure at environmentally relevant dose promoted ovarian cancer progression and modulated tumor microenvironment through β-catenin/SPP1 axis., PMID:40054195
Denosumab Enhances Antitumor Immunity by Suppressing SPP1 and Boosting Cytotoxic T Cells., PMID:40009710
Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1+ monocytes-derived macrophages., PMID:39919902
M2 macrophages regulate nucleus pulposus cell extracellular matrix synthesis through the OPN-CD44 axis in intervertebral disc degeneration., PMID:39842659
The Association of Anti-Sm with Osteopontin Related to Cognitive Impairment in a Pristane-Induced Lupus BALB/c Mice Model., PMID:39684790
CXCL12-Targeted Immunomodulatory Gene Therapy Reduces Radiation-Induced Fibrosis in Healthy Tissues., PMID:39666014
Two-sided function of osteopontin during osteoblast differentiation., PMID:39658208
Osteopontin neutralization increases vitamin D receptors on NKT cells and ameliorates liver fibrosis by promoting their activity., PMID:39654627
Suppression of renal crystal formation, inflammation, and fibrosis by blocking oncostatin M receptor β signaling., PMID:39572752
Echinochrome A inhibits HMGB1-induced vascular smooth muscle cell migration by suppressing osteopontin expression., PMID:39539178
Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells., PMID:39484394
OPN-Mediated Crosstalk Between Hepatocyte E4BP4 and Hepatic Stellate Cells Promotes MASH-Associated Liver Fibrosis., PMID:39473081
Overcoming Irinotecan Resistance by Targeting Its Downstream Signaling Pathways in Colon Cancer., PMID:39456585
Combined proteomics and metabolomics analysis reveal the effect of a training course on the immune function of Chinese elite short-track speed skaters., PMID:39352112
FHL2 expression by cancer-associated fibroblasts promotes metastasis and angiogenesis in lung adenocarcinoma., PMID:39244734
TLR2 immunotherapy suppresses neuroinflammation, tau spread, and memory loss in rTg4510 mice., PMID:39098437
Niobium carbide MXenzyme-Driven comprehensive cholesterol regulation for photoacoustic image-guided and anti-inflammatory photothermal ablation in atherosclerosis., PMID:39072287
Immunogenicity and Safety Following 1 Dose of AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults: A Phase 3 Trial., PMID:39052726
ETV5 promotes lupus pathogenesis and follicular helper T cell differentiation by inducing osteopontin expression., PMID:38843187
Fibroblasts from HPV-negative oropharynx squamous cell carcinomas stimulate the release of osteopontin from cancer cells via the release of IL-6., PMID:38803348
Baseline urinary osteopontin levels are associated with the improvement of metabolic syndrome., PMID:38664124
The development of lateral flow devices for urinary biomarkers to assess kidney health., PMID:38609491
Circulating Osteopontin Predicts Clinical and Radiological Response in First-Line Treatment of Advanced Non-Small Cell Lung Cancer., PMID:38480620
Osteopontin, osteoprotegerin and musculoskeletal ultrasound findings in first-degree relatives of rheumatoid arthritis: potential markers of preclinical disease., PMID:38443806
Prognostic and predictive analyses of circulating plasma biomarkers in men with metastatic castration resistant prostate cancer treated with docetaxel/prednisone with or without bevacizumab., PMID:38347114
Bilateral retrobulbar optic neuritis combined with optic perineuritis associated with atezolizumab treatment for small cell lung carcinoma., PMID:38178774
Associations of serum keratin 1 with thyroid function and immunity in Graves' disease., PMID:38019813
Osteopontin Concentration in Prostates Fractions: A Novel Marker of Sperm Quality in Dogs., PMID:37999469
Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses., PMID:37935952
1,25-Dihydroxyvitamin D3: A Positive Factor for the Osteogenic Differentiation of hPDLSCs and for the Tissue Regenerative Activity of Cell Sheets., PMID:37798942
Associations Between Osteopontin Variants and Systemic Lupus Erythematosus: A Meta-Analysis., PMID:37695811
Osteopontin levels correlate with severity of diabetic cardiomyopathy in early stage of diabetes., PMID:37598938
Osteopontin expression and the effect of anti-VLA-4 mAb treatment in experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis., PMID:37587887
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways., PMID:37586160
Impact of dual neutralization of TNF-α and IL-1β along with Gentamicin treatment on the functions of blood and splenic neutrophils and its role on improvement of S. aureus induced septic arthritis., PMID:37572502
Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis., PMID:37535809
Comparative Study of the Cytokine Profiles of Serum and Tissues from Patients with the Ossification of the Posterior Longitudinal Ligament., PMID:37509659
Radiographic and immuno-histochemical evaluation of root perforation repair using MTA with or without platelet-rich fibrin or concentrated growth factors as an internal matrix in dog's teeth: in vivo animal study., PMID:37500933
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15., PMID:37468019
Osteopontin (OPN) alleviates the progression of osteoarthritis by promoting the anabolism of chondrocytes., PMID:37397527
A targeted isotope dilution mass spectrometry assay for osteopontin quantification in plasma of metastatic breast cancer patients., PMID:37384615
Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA., PMID:37340499
Complexity of Inflammation in the Trajectory of Vascular Disease: Interleukin 6 and Beyond., PMID:37006867
Serum osteopontin predicts the response to atezolizumab plus bevacizumab in patients with hepatocellular carcinoma., PMID:36991155
For research use only. Not for human or drug use.
