Catalog No.
YHC31801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp724
Predicted molecular weight
85.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08238
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSPC2, HSP 90, HSP90B, Heat shock protein HSP 90-beta, Heat shock 84 kDa, HSPCB, HSP84, HSP90AB1, HSP 84
Investigation of cognitive enhancements and mechanisms of kinsenoside in APP/PS1 mice through network pharmacology, in vivo experiments, and machine learning., PMID:40513940
Maternal High-Fat Diet-Induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins., PMID:40513769
Unraveling Botulinum Neurotoxin A Light-Chain-Induced Signaling Pathways: A Phosphoproteomic Analysis in a Controlled Cellular Model., PMID:40507977
Strong Hsp90α/β Protein Expression in Advanced Primary CRC Indicates Short Survival and Predicts Response to the Hsp90α/β-Specific Inhibitor Pimitespib., PMID:40498011
Exploring the anti-gastric cancer mechanisms of Diosgenin through integrated network analysis, bioinformatics, single-cell sequencing, and cell experiments., PMID:40487391
HNRNPH1 promotes autophagy to inhibit the development of lung adenocarcinoma via the HSP90AB1/MAP1LC3B axis., PMID:40468317
Identification of multiomics and immune infiltration-associated biomarkers for early gastric cancer: a machine learning-based diagnostic model development study., PMID:40450287
Computational investigation and experimental validation of the molecular mechanism of Solanecio mannii aqueous roots extract against cervical cancer., PMID:40446016
TCF7 enhances pulmonary hypertension by boosting stressed natural killer cells and their interaction with pulmonary arterial smooth muscle cells., PMID:40442690
The chaperones HSP90AA1, HSP90AB1 and BAG3 are specifically distributed among human hippocampal subfields during different Alzheimer's disease stages., PMID:40436281
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics., PMID:40421421
Honokiol in the treatment of triple-negative breast cancer: a network pharmacology approach and experimental validation., PMID:40398092
Exploring the antitumor potential of cucurbitacin B in hepatocellular carcinoma through network pharmacology, molecular docking, and molecular dynamics simulations., PMID:40397117
HSP90 and the cancer transcriptome: a comprehensive review of inhibitors and mechanistic insights., PMID:40383747
Quantitative Proteomic Analysis of Cardiac Xenograft Failure in a Pig-to-Non-Human Primate Model Identifies NF-κB as a Critical Immunomodulatory Target., PMID:40375624
LGR5 interacts with HSP90AB1 to mediate enzalutamide resistance by activating the WNT/β-catenin/AR axis in prostate cancer., PMID:40280884
The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification., PMID:40259338
Association between hyperlipidemia and nephrolithiasis: A comprehensive bioinformatics analysis deciphering the potential common denominator pathogenesis., PMID:40245021
Reversal of sorafenib resistance in hepatocellular carcinoma by curcumol: insights from network pharmacology, molecular docking, and experimental validation., PMID:40242448
Screening colorectal cancer associated autoantigens through multi-omics analysis and diagnostic performance evaluation of corresponding autoantibodies., PMID:40240912
Application of network pharmacology, bioinformatics, computational molecular docking, and experimental validation to study the anticancer effects of oleanolic acid in oral squamous carcinoma cells., PMID:40208786
The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid., PMID:40194363
The N6-methyladenosine reader IGF2BP3 promotes bladder cancer progression through enhancing HSP90AB1 expression., PMID:40105114
Identification of key LncRNAs and mRNAs associated with intramuscular fat in pig via WGCNA., PMID:40069611
Histone chaperones as potential epidrug targets against cancer., PMID:40059533
Identifying gene expression and cellular pathways involved in glomerular AL-amyloidosis and correlation with experimental data: seeking novel therapeutic interventions., PMID:39985165
Study of Hsp90α and Hsp90β role in virus replication using cell lines with Hsp90 gene knockouts., PMID:39948206
Identification of critical genes and drug repurposing targets in entorhinal cortex of Alzheimer's disease., PMID:39928227
Dehydroepiandrosterone ameliorates primary dysmenorrhea by suppressing the SP1/Hsp90ab1/COX-2 signaling pathway., PMID:39914036
Assessment of Hsp90β-selective inhibitor safety and on-target effects., PMID:39880847
BRN3A, a transcription factor, regulates the expression of genes involved in biological processes shaping the HPV induced cervical cancer., PMID:39873931
IKZF1 promotes pyroptosis and prevents M2 macrophage polarization by inhibiting JAK2/STAT5 pathway in colon cancer., PMID:39862997
Proteomics Reveals the Response Mechanism of Embryonic Bovine Lung Cells to Mycoplasma bovis Infection., PMID:39859536
Study on mechanism of Spatholobi Caulis in the treatment of the hand-foot skin reaction induced by targeted drug therapy based on network pharmacology and molecular docking: An observational study., PMID:39792751
circTP63-N suppresses the proliferation and metastasis of nasopharyngeal carcinoma via engaging with HSP90AB1 to modulate the YAP1/Hippo signaling pathway., PMID:39754006
Potential molecular mechanisms of tobacco smoke exposure in Alzheimer's disease., PMID:39694170
Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer., PMID:39671399
Molecular response of canine testis to GnRH agonist: Insights into AR, HIF-1α, and HSPs expression during arrest and recovery of spermatogenesis., PMID:39631561
Unveiling biomarker detection in Alzheimer's disease: a computational approach to microarray analysis., PMID:39606011
Decoding neuronal genes in stroke-induced pain: insights from single-nucleus sequencing in mice., PMID:39581982
Genomic regions and biological mechanisms underlying climatic resilience traits derived from automatically-recorded vaginal temperature in lactating sows under heat stress conditions., PMID:39574795
Integrating Metabolomic Analysis, Network Pharmacology, and Molecular Docking to Underlying Pharmacological Mechanism and Ethnobotanical Rationalization for Diabetes Mellitus: Study on Medicinal Plant Fibraurea tinctoria Lour., PMID:39539006
GLCCI1 alleviates GRP78-initiated endoplasmic reticulum stress-induced apoptosis of retinal ganglion cells in diabetic retinopathy by upregulating and interacting with HSP90AB1., PMID:39496608
Exploring the Regulatory Interaction of Differentially Expressed Proteins in Cleft Palate Induced by Retinoic Acid., PMID:39473103
Ubiquitin-related gene markers predict immunotherapy response and prognosis in patients with epithelial ovarian carcinoma., PMID:39448713
Bioinformatics data combined with single-cell analysis reveals patterns of immunoinflammatory infiltration and cell death in melanoma., PMID:39418727
Effects of treadmill exercise on endoplasmic reticulum protein folding and endoplasmic reticulum-associated protein degradation pathways in APP/PS1 mice., PMID:39397952
LncRNA HAR1A inhibits non-small cell lung cancer growth by downregulating c-MYC transcripts and facilitating its proteasomal degradation., PMID:39340992
Unveiling proteomic targets in the hypothalamus of ovariectomized and estradiol-treated rats: Insights into menopausal syndrome mechanisms., PMID:39326767
Single-cell RNA sequencing reveals the communications between tumor microenvironment components and tumor metastasis in osteosarcoma., PMID:39324133
For research use only. Not for human or drug use.
