Catalog No.
RHC44201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
5-LO, ALOX5, LOG5, Polyunsaturated fatty acid 5-lipoxygenase, 5-lipoxygenase, Arachidonate 5-lipoxygenase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P09917
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1M33
Xin-Yi-Qing-Fei-Tang and its critical components reduce asthma symptoms by suppressing GM-CSF and COX-2 expression in RBL-2H3 cells., PMID:38631485
Immunohistochemical analysis of arachidonate 5-lipoxygenase expression in B-cell lymphomas: Implication for B cell differentiation and its analogy with lymphomagenesis., PMID:36689839
Evaluation of You-Gui-Wan critical compounds inhibiting ALOX-5 and HDC gene expression in RBL-2H3 cells using a fractional factorial design., PMID:36610671
Analysis of proximal ALOX5 promoter binding proteins by quantitative proteomics., PMID:32096311
Frontline Science: A reduction in DHA-derived mediators in male obesity contributes toward defects in select B cell subsets and circulating antibody., PMID:30576001
Biosynthesis of proresolving lipid mediators by vascular cells and tissues., PMID:28442547
Comparative Expression Analyses of Pro- versus Anti-Inflammatory Mediators within Synovium of Patients with Joint Trauma, Osteoarthritis, and Rheumatoid Arthritis., PMID:28316377
Lipid mediators foster the differentiation of T follicular helper cells., PMID:27838468
Genetic Predictors of Drug Hypersensitivity., PMID:27779086
Genetic variants associated with drugs-induced immediate hypersensitivity reactions: a PRISMA-compliant systematic review., PMID:26678823
Tocilizumab attenuates inflammation in ALS patients through inhibition of IL6 receptor signaling., PMID:23383400
Cyclooxygenase-2 generates the endogenous mutagen trans-4-hydroxy-2-nonenal in Enterococcus faecalis-infected macrophages., PMID:23321929
A novel function of IL-2: chemokine/chemoattractant/retention receptor genes induction in Th subsets for skin and lung inflammation., PMID:22464450
Arachidonate 5-lipoxygenase establishes adaptive humoral immunity by controlling primary B cells and their cognate T-cell help., PMID:21224059
ALOX5 promoter genotype and response to montelukast in moderate persistent asthma., PMID:18339529