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Anti-GLA Antibody (R1K52)

Catalog #:   RHC19501 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, IP, WB
Accession: P06280
Overview

Catalog No.

RHC19501

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000

Target

Alpha-D-galactosidase A, Galactosylgalactosylglucosylceramidase GLA, GLA, Melibiase, Agalsidase, Alpha-D-galactoside galactohydrolase, Alpha-galactosidase A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06280

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1K52

Data Image
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Galactosidase alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of Galactosidase alpha in K562 lysates using Galactosidase alpha antibody.
References

Beta-2 microglobulin in lymphoma., PMID:40490112

Enzyme replacement therapy using a modified α-N-acetylgalactosaminidase to suppress progressive glycolipid accumulation and escape from antidrug antibody formation in young human NAGA-transgenic/Gla-knockout mice., PMID:40446427

Estimating population immunity to SARS-CoV-2 by random sampling from primary and secondary healthcare in Scotland, May 2024., PMID:40381379

PRRG4 Brain-Specific Conditional Knockout Mice Display Autism Spectrum Disorder-Like Behaviors., PMID:40380139

A polyvalent DNA prime with matched polyvalent protein/GLA-SE boost regimen elicited the most robust and broad IgG and IgG3 V1V2 binding antibody and CD4+ T cell responses among 13 HIV vaccine trials., PMID:40190112

Safety and implementation of phase I randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns., PMID:40178906

Lectin-Based Substrate Detection in Fabry Disease Using the Gb3-Binding Lectins StxB and LecA., PMID:40076891

Antibodies are predictive for diagnosis of celiac disease in pediatric type 1 diabetes., PMID:40056457

A Pentavalent HIV-1 Subtype C Vaccine Containing Computationally Selected gp120 Strains Improves the Breadth of V1V2 Region Responses., PMID:40006680

Clinical Insights into Protein-based Therapies for Precision Targeting of Psoriasis., PMID:39936423

[Non-Hodgkin's lymphomas: a short overview]., PMID:39932516

Phosphatidylserine (PS)-targeting chimeric Interferon (IFN) fusion proteins for anti-tumor applications., PMID:39896467

Posterior Positivity Distribution Analysis of Subclinical Bluetongue in the Eastern and North-Eastern States of India: A Wakeup Call for Outbreak Preparedness., PMID:39861807

Use of a mouse-human chimeric anti-α-galactosidase A monoclonal antibody as a reference for measuring serum antidrug antibody titers in patients with Fabry disease., PMID:39693814

Emerging AXL Inhibitors in Oncology: Chemical and Biological Advances in Targeted Cancer Therapy., PMID:39679460

HVTN 123: A Phase 1, Randomized Trial Comparing Safety and Immunogenicity of CH505TF gp120 Produced by Stably and Transiently Transfected Cell Lines., PMID:39671174

Exploring the potential of TGFβ as a diagnostic marker and therapeutic target against cancer., PMID:39577704

Immunogenicity of intraperitoneal and intranasal liposome adjuvanted VLP vaccines against SARS-CoV-2 infection., PMID:39516286

Safety and implementation of a phase 1 randomized GLA-SE-adjuvanted CH505TF gp120 HIV vaccine trial in newborns., PMID:39484284

Immunotherapy in Alzheimer's Disease: Current Status and Future Directions., PMID:39422934

Protection of Broiler Chickens Against Necrotic Enteritis by Intrapulmonary Delivery of a Live Clostridium perfringens Vaccine Exploiting the Gut-Lung-Axis Concept., PMID:39400219

Co-regulation of innate and adaptive immune responses induced by ID93+GLA-SE vaccination in humans., PMID:39381003

Programmable bionanomaterials for revolutionizing cancer immunotherapy., PMID:39291418

Identification of reactive Borrelia burgdorferi peptides associated with Lyme disease., PMID:39248571

Immunogenicity and safety of an Entamoeba histolytica adjuvanted protein vaccine candidate (LecA+GLA-3M-052 liposomes) in rhesus macaques., PMID:39090779

A comparative immunological assessment of multiple clinical-stage adjuvants for the R21 malaria vaccine in nonhuman primates., PMID:39083589

Enhancing carboplatin sensitivity in ovarian cancer cells by blocking the mercapturic acid pathway transporter., PMID:39051454

Protocol of a prospective multicenter study on comorbidity impact on multiple sclerosis and antibody-mediated diseases of the central nervous system (COMMIT)., PMID:39021565

Cancer treatment with biosimilar drugs: A review., PMID:38946928

Glycerides of lauric acid supplementation in the chicken diet enhances the humoral and cellular immune response to infectious bronchitis virus., PMID:38924873

Usefulness of antibody-drug conjugate as preconditioning for hematopoietic stem cell-targeted gene therapy in wild-type and Fabry disease mouse models., PMID:38820907

[Current Standards in the Treatment of Hodgkin Lymphoma]., PMID:38781993

Lymphatic endothelial cell-specific NRAS p.Q61R mutant embryos show abnormal lymphatic vessel morphogenesis., PMID:38743908

[Not Available]., PMID:38704747

Safety and immunogenicity of a polyvalent DNA-protein HIV vaccine with matched Env immunogens delivered as a prime-boost regimen or coadministered in HIV-uninfected adults in the USA (HVTN 124): a phase 1, placebo-controlled, double-blind randomised controlled trial., PMID:38692824

Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction., PMID:38670093

Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, phase 1, dose-escalation trial., PMID:38513684

Rituximab, gemcitabine and oxaliplatin in relapsed or refractory indolent and mantle cell lymphoma: results of a multicenter phase I/II-study of the German Low Grade Lymphoma Study Group., PMID:38459156

Evaluation of immunomodulatory (humoral as well as cell-mediated) and cytokines (TNF-α & IL-10) regulating potential of Neolamarckia cadamba fruit extract in Wistar albino rats., PMID:38456082

IgG Subclass Switch in Volunteers Repeatedly Immunized with the Full-Length Plasmodium falciparum Merozoite Surface Protein 1 (MSP1)., PMID:38400191

Recombinant Full-length Plasmodium falciparum Circumsporozoite Protein-Based Vaccine Adjuvanted With Glucopyranosyl Lipid A-Liposome Quillaja saponaria 21: Results of Phase 1 Testing With Malaria Challenge., PMID:38330357

Reducing agalsidase beta infusion time in Fabry patients: low incidence of antibody formation and infusion-associated reactions in an Italian multicenter study., PMID:38308295

Complement activation and cellular inflammation in Fabry disease patients despite enzyme replacement therapy., PMID:38304433

The emergence and implications of SARS-CoV-2 omicron subvariant BA.2.86 on global health., PMID:38215252

Antibody-drug conjugates in cancer therapy: innovations, challenges, and future directions., PMID:38153656

Immunological depiction of synthetic B-cell epitopes of Mycobacterium tuberculosis., PMID:38149531

Effects of switching from agalsidase-α to agalsidase-β on biomarkers, renal and cardiac parameters, and disease severity in fabry disease forming neutralizing antidrug antibodies: a case report., PMID:38135868

Characterization of Gla proteoforms and non-Gla peptides of gamma carboxylated proteins: Application to quantification of prothrombin proteoforms in human plasma., PMID:37996163

Infection, Inflammation, and Immunity in Sepsis., PMID:37759732

Antiviral Drugs and Vaccines for Omicron Variant: A Focused Review., PMID:37719798

Datasheet

Document Download

Anti-GLA Antibody (R1K52).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-GLA Antibody (R1K52) [RHC19501]
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