Catalog No.
YHC28801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met263-Asp491
Predicted molecular weight
28.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07948
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lck/Yes-related novel protein tyrosine kinase, p53Lyn, JTK8, p56Lyn, Tyrosine-protein kinase Lyn, LYN, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus., PMID:40506261
Curcumenol Inhibits Mast Cells Activation in Ovalbumin-Induced Anaphylaxis Model Mice through Modulation of the Fc Epsilon Receptor I Signaling Pathway., PMID:40503570
Physiochemical and transcriptomics of exotic holstein friesian cattle in Pakistani subtropics., PMID:40478316
Advances in sulfonyl exchange chemical biology: expanding druggable target space., PMID:40443986
NAMPT-mediated deacetylation of HCLS1 protein promotes clonogenic growth of pediatric CML cells., PMID:40349748
Identifying potential tear biomarkers in premature infants with retinopathy of prematurity based on proteome and transcriptome analysis., PMID:40343554
Liangxue Qushi Zhiyang Decoction Inhibits Atopic Dermatitis in Mice via FcγR-Mediated Phagocytosis., PMID:40322063
Macrophage Lyn Kinase Is a Sex-Specific Regulator of Post-Subarachnoid Hemorrhage Neuroinflammation., PMID:40281655
Development and characterization of the novel MYD88 mutated, 6q deleted BCWM.2 cell line for Waldenström macroglobulinaemia., PMID:40254718
Protectin D1, an omega-3-derived lipid mediator, resolves mast cell-driven allergic inflammation via FcεRⅠ signaling., PMID:40253829
Microglial TLR4-Lyn kinase is a critical regulator of neuroinflammation, Aβ phagocytosis, neuronal damage, and cell survival in Alzheimer's disease., PMID:40175501
Role of Lyn Immunohistochemical Staining in Progression of Colorectal Carcinoma., PMID:40156411
Structure-guided design of a truncated heterobivalent chemical probe degrader of IRE1α., PMID:40151563
Functional Role of Fatty Acid Synthase for Signal Transduction in Core-Binding Factor Acute Myeloid Leukemia with an Activating c-Kit Mutation., PMID:40149597
Daxx Variation as a Potential Predictive Marker of the Therapeutic Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer., PMID:40130316
Identification of potential biomarkers and therapeutic targets in psoriasis based on NF-κB pathway-related genes., PMID:40119934
FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells., PMID:40116400
Protocatechuic Acid Reduces Liver Fatty Acid Uptake in HFD-Fed Mice Associated With the Inhibition of DHHC5-Mediated CD36 Palmitoylation., PMID:40109131
Identifcation of the FGF family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:40086631
Selective Azapeptide CD36 Ligand MPE-298 Regulates oxLDL-LOX-1-Mediated Inflammation and Mitochondrial Oxidative Stress in Macrophages., PMID:40072113
Glial Alterations in the Glutamatergic and GABAergic Signalling Pathways in a Mouse Model of Lafora Disease, a Severe Form of Progressive Myoclonus Epilepsy., PMID:40035482
Direct neutrophil and T cell contact with macrophages induces release of phagosomally processed PAMPs via eructophagy., PMID:40019316
Bioinformatics analysis of shared biomarkers and immune pathways of preeclampsia and periodontitis., PMID:40016711
Megakaryocytes transfer mitochondria to bone marrow mesenchymal stromal cells to lower platelet activation., PMID:40014405
Nauclofficines A and B, two novel monoterpenoid indole alkaloids from the Li folk herb Nauclea officinalis with anti-allergic inflammatory effects on RBL-2H3 cells., PMID:39987995
Genetic insights into avian influenza resistance in Jeju Island chickens: the roles of Mx1 and oligoadenylate synthetase-like single nucleotide polymorphisms., PMID:39974787
EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI., PMID:39972345
Inflammatory/Immune Adverse Events in Chronic Myeloid Leukemia Patients During Treatment With Bosutinib., PMID:39910922
Identification of Immune Infiltration-Associated CC Motif Chemokine Ligands as Biomarkers and Targets for Colorectal Cancer Prevention and Immunotherapy., PMID:39859340
Perfluorooctane sulfonate attenuates IgE/Ag-stimulated mast cell activation and anaphylactic responses via activating SHP-1 pathway., PMID:39827624
Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase., PMID:39815634
Identification of critical endoplasmic reticulum stress-related genes in advanced atherosclerotic plaque., PMID:39814777
AMPK: An energy sensor for non-small cell lung cancer progression and treatment., PMID:39805353
Dietary Linolenic Acid Enhances IgE Binding to Bovine α-Lactalbumin/β-Lactoglobulin and Promotes KU812 Basophil Degranulation via Upregulation of the Lyn/Syk Pathway., PMID:39772611
Generation of a human induced pluripotent stem cell line (CRICKi021-A) from a patient with Ullrich congenital muscular dystrophy carrying a pathogenic mutation in the COL6A1 gene., PMID:39764974
Proteomic analysis of wanxi white goose testicles in different reproductive stages by data-independent acquisition (DIA) strategy., PMID:39752991
Conjugated Linoleic Acid (CLA) Mitigates High-Fat Diet (HFD)-Induced Mammary Gland Development Impairment of Pubertal Mice via Regulating CD36 Palmitoylation and Downstream JNK-ERK Pathway., PMID:39752534
Targeted exonic sequencing identifies novel variants in a cerebral small vessel disease cohort., PMID:39743006
Cross-modal sensory compensation increases mosquito attraction to humans., PMID:39742477
Whole exome sequencing analysis of a patient with myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions with ETV6::LYN fusion gene., PMID:39704842
FcRγIIA attenuates pathology of cutaneous leishmaniasis and modulates ITAMa/i balance., PMID:39696675
KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE-mediated Activation., PMID:39676406
The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling., PMID:39665272
Unraveling pathogenesis and potential biomarkers for autism spectrum disorder associated with HIF1A pathway based on machine learning and experiment validation., PMID:39657846
Isobavachin attenuates FcεRI-mediated inflammatory allergic responses by regulating SHP-1-dependent Fyn/Lyn/Syk/Lck signaling., PMID:39643121
Aberrantly Expressed Mitochondrial Lipid Kinase, AGK, Activates JAK2-Histone H3 Axis and BCR Signal: A Mechanistic Study with Implication in CLL Therapy., PMID:39636206
Cas10 relieves host growth arrest to facilitate spacer retention during type III-A CRISPR-Cas immunity., PMID:39626678
FGF receptor kinase inhibitors exhibit broad antiviral activity by targeting Src family kinases., PMID:39621133
CD11b deficiency attenuates the ischemia/reperfusion-induced AKI-to-CKD process by regulating macrophage polarization., PMID:39612192
Reverse Vaccinology and Immunoinformatics Strategy to Screen Oncogenic Proteins and Development of a Multiepitope Peptide Vaccine Targeting Protein Kinases against Oral Cancer: An in-silico Study., PMID:39611932
For research use only. Not for human or drug use.
