Catalog No.
RHC15201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
CYP2E, 4-nitrophenol 2-hydroxylase, CYP2E1, Cytochrome P450 2E1, CYPIIE1, Cytochrome P450-J
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05181
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1K16
High dose acetaminophen re-polarizes CD11b+ cells in the tumor microenvironment towards an activated macrophage phenotype., PMID:40158231
Lipid nanoparticle delivery of siRNA targeting Cyp2e1 gene attenuates subacute alcoholic liver injury in mice., PMID:37476942
Serum interleukin-4 is elevated in clinical drug-induced liver injury., PMID:37464727
Focal adhesion alterations in G0-positive melanoma cells., PMID:36533319
Increased serum anti-CYP2E1 IgG autoantibody levels may be involved in the pathogenesis of occupational trichloroethylene hypersensitivity syndrome: a case-control study., PMID:35763063
Plum Prevents Intestinal and Hepatic Inflammation in the Acute and Chronic Models of Dextran Sulfate Sodium-Induced Mouse Colitis., PMID:35476900
Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice., PMID:35024307
Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid., PMID:31726965
Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes., PMID:31585129
Characterization of Cellular Sources and Circulating Levels of Extracellular Vesicles in a Dietary Murine Model of Nonalcoholic Steatohepatitis., PMID:31497744
Cytochrome P450 2E1-deficient MRL+/+ mice are less susceptible to trichloroethene-mediated autoimmunity: Involvement of oxidative stress-responsive signaling pathways., PMID:31446053
Fructose Promotes Leaky Gut, Endotoxemia, and Liver Fibrosis Through Ethanol-Inducible Cytochrome P450-2E1-Mediated Oxidative and Nitrative Stress., PMID:30959577
Effect of Stem Cell Treatment on Acute Liver Failure Model Using Scaffold., PMID:30421375
CYP2J2 is the major enzyme in human liver microsomes responsible for hydroxylation of SYL-927, a novel and selective sphingosine 1-phosphate receptor 1 (S1P1 ) agonist., PMID:30362120
Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis., PMID:30305319
Featured structure-activity relationships for some tri- and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity - Impact of the extent of ortho-chlorination., PMID:30025364
The Impact of Drug Metabolism Gene Polymorphisms on Therapeutic Response and Survival in Diffuse Large B-Cell Lymphoma Patients., PMID:29629728
Proteomic Characteristics of Blood Serum in Rats with Different Behavioral Parameters after Acute Stress., PMID:28361418
Development of an IgY Antibody-Based Immunoassay for the Screening of the CYP2E1 Inhibitor/Enhancer from Herbal Medicines., PMID:28066249
Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice., PMID:27694226
Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles., PMID:26632633
Evaluation of Risk Factors for Nasopharyngeal Carcinoma in a High-risk Area of India, the Northeastern Region., PMID:26163617
The Protective Roles of IL-6 Trans-Signaling Regulated by ADAM9 on the Liver in Carbon Tetrachloride-Induced Liver Injury in Mice., PMID:26044069
Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease., PMID:26006114
Expression of CYP2E1 and CYP2U1 proteins in amygdala and prefrontal cortex: influence of alcoholism and smoking., PMID:25872594
Comprehensive kinetic analysis and influence of reaction components for chlorzoxazone 6-hydroxylation in human liver microsomes with CYP antibodies., PMID:25815637
Hypothesis of demodicidosis rosacea flushing etiopathogenesis., PMID:25683389
CYP2E1 autoantibodies in liver diseases., PMID:25462068
Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine., PMID:25138712
Characterization of arachidonic acid metabolism by rat cytochrome P450 enzymes: the involvement of CYP1As., PMID:24969701
CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia., PMID:24868327
Association studies of cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1) gene polymorphisms with acute rejection in kidney transplantation recipients., PMID:24654912
Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys., PMID:24593267
Expression of selected cytochrome P450 isoforms and of cooperating enzymes in colorectal tissues in selected pathological conditions., PMID:24485758
Ethanol plus the Jo2 Fas agonistic antibody-induced liver injury is attenuated in mice with partial ablation of argininosuccinate synthase., PMID:24224890
Quantification of cytochrome 2E1 in human liver microsomes using a validated indirect ELISA., PMID:24184659
Isoniazid hepatotoxicity: progress in understanding the immunologic component., PMID:24037911
Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure., PMID:23775837
Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter pylori infection., PMID:23686565
Hepatoprotective effect of water extract from Chrysanthemum indicum L. flower., PMID:23557275
Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: a critical role for E-selectin., PMID:23532958
Prilocaine- and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation., PMID:23530020
Nicotinamide N-oxidation by CYP2E1 in human liver microsomes., PMID:23418369
Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes., PMID:23010222
Development and validation of an enzyme-linked immunosorbent assay for the quantification of cytochrome 3A4 in human liver microsomes., PMID:22967564
The dual role of osteopontin in acetaminophen hepatotoxicity., PMID:22728710
Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with baicalin., PMID:22699086
Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin., PMID:22584460
The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism., PMID:22558931
Murine collagen antibody induced arthritis (CAIA) and primary mouse hepatocyte culture as models to study cytochrome P450 suppression., PMID:22425536
For research use only. Not for human or drug use.
