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Anti-APP Antibody (R1J90)

Catalog #:   RHC12515 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: P05067
Overview

Catalog No.

RHC12515

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000

Target

AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05067

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1J90

Data Image
  • Immunofluorescence
    Immunocytochemistry analysis of Amyloid Precursor Protein(green) in Hela using Amyloid Precursor Protein antibody,and DAPI(blue).
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Amyloid Precursor Protein antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of Amyloid Precursor Protein in mouse brain lysates using Amyloid Precursor Protein antibody.
  • Western blot
    Western blot analysis of Amyloid Precursor Protein in rat Brain lysates using Amyloid Precursor Protein antibody.
References

Unique lipid cargoes in APOE4 human brain-derived extracellular vesicles recruit cell adhesion molecules and promote tauopathy in Alzheimer's disease., PMID:40502793

Enhancing Human Post-Exposure Rabies Prophylaxis in Canine Rabies Endemic Regions With an Interactive Web Solution., PMID:40496118

β-Amyloid as a new target to suppress tonic PTH hypersecretion in primary hyperparathyroidism., PMID:40492090

Soluble VCAM-1 may serve as a pharmacodynamic CSF marker to monitor BACE2 activity in non-human primates., PMID:40480341

Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis., PMID:40455292

Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life., PMID:40442822

PET imaging of TREM2 in amyloid-beta induced neuroinflammation., PMID:40434494

Immune impacts of infant whole-cell and acellular pertussis vaccination on co-administered vaccines., PMID:40414565

Live attenuated hfq-deleted Acinetobacter baumannii vaccine provides protection against systemic infection., PMID:40412336

Discovery of an APP-selective BACE1 inhibitor for Alzheimer's disease., PMID:40399225

Co-occurrence of Down Syndrome and Multiple Sclerosis., PMID:40395918

A fully automated paper-based smartphone-assisted microfluidic chemiluminescence sample to result immunoassay platform., PMID:40374237

Probe-free and wash-free strategy for on-site testing of chloramphenicol in food based on differential encodable microspheres separation system., PMID:40359682

Development and Characterization of a Recombinant galT-galU Protein for Broad-Spectrum Immunoprotection Against Porcine Contagious Pleuropneumonia., PMID:40332240

Strategies Beyond 3rd EGFR-TKI Acquired Resistance: Opportunities and Challenges., PMID:40322930

Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs., PMID:40307937

Field Evaluation of a Ready-to-Use Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Vaccine in Naturally Infected Farms in Taiwan., PMID:40284806

Blockage of CCL3 with neutralizing antibody reduces neuroinflammation and reverses Alzheimer disease phenotypes., PMID:40268067

Novel Soluble apxIVA-Truncated Protein and Its Application to Rapid Detection and Distinction of Actinobacillus pleuropneumoniae Wild-Strain-Infected Samples from Those Vaccinated with apxIV-Partially Deleted Vaccine., PMID:40266988

Combination of anlotinib with immunotherapy enhanced both anti-angiogenesis and immune response in high-grade serous ovarian cancer., PMID:40260248

Novel Approaches to Track Neurodegeneration in Murine Models of Alzheimer's Disease Reveal Previously Unknown Aspects of Extracellular Aggregate Deposition., PMID:40236040

Clinical Benefits and Risks of Antiamyloid Antibodies in Sporadic Alzheimer Disease: Systematic Review and Network Meta-Analysis With a Web Application., PMID:40194268

Establishing the lowest penicillin concentration to prevent pharyngitis due to Streptococcus pyogenes using a human challenge model (CHIPS): a randomised, double-blind, placebo-controlled trial., PMID:40157384

Distinguishing Low Expression Levels of Human Epidermal Growth Factor Receptor 2 in Breast Cancer: Insights from Qualitative and Quantitative Magnetic Resonance Imaging Analysis., PMID:40137571

Multianalyte Nanopore Detection of Alzheimer's Biomarkers: A Label-Free Platform with Improved Sensitivity and Range., PMID:40129019

Combination therapy with Chicoric acid and PD-1/PD-L1 blockade improves the immunotherapy response in patient-derived ovarian cancer xenograft model., PMID:40087780

Spatial prediction of immunity gaps during a pandemic to inform decision making: A geostatistical case study of COVID-19 in Dominican Republic., PMID:40074535

A novel flow through assay and smartphone application based prototype for point-of-care diagnosis of tuberculosis., PMID:40049786

Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease., PMID:40027647

Individual Genomic Loci, Transcript Level and Serum Profile of Immune, Antioxidant and Hormonal Markers Associated with Sheep Arthritis., PMID:40005882

Capturing what matters: Patient-reported LGI1-ANTibody encephalitis outcome RatiNg scale (LANTERN)., PMID:39996410

Predicting and validating the risk of interstitial lung disease in systemic lupus erythematosus., PMID:39986125

Concepts and Methods for Predicting Viral Evolution., PMID:39890732

Bone marrow mesenchymal stem cells derived cytokines associated with AKT/IAPs signaling ameliorate Alzheimer's disease development., PMID:39849525

Immunogenicity and vaccine efficacy of Actinobacillus pleuropneumoniae-derived extracellular vesicles as a novel vaccine candidate., PMID:39831520

Immunotherapy-Resistant Neuropathic Pain and Fatigue Predict Quality-of-Life in Contactin-Associated Protein-Like 2 Antibody Disease., PMID:39825737

Magnetofluidic-Assisted Portable Automated Microfluidic Devices for Protein Detection., PMID:39815389

Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy., PMID:39813317

Toward curing neurological autoimmune disorders: Biomarkers, immunological mechanisms, and therapeutic targets., PMID:39809275

Equipmentless point-of-care testing of dengue antibodies using ELISA and smartphones., PMID:39787848

Can GastroPanel be used as a triage tool to select patients with advanced atrophic gastritis for gastroscopy? A prospective clinical validation study., PMID:39762070

Smartphone-based mobile digital pressure sensor for quantitative point-of-care testing of respiratory syncytial virus infection., PMID:39756256

Immunohistochemical labeling of ongoing axonal degeneration 10 days following cervical contusion spinal cord injury in the rat., PMID:39753895

Acute Communication Between Microglia and Nonparenchymal Immune Cells in the Anti-Aβ Antibody-Injected Cortex., PMID:39741000

Effectiveness of a Novel PLA2R1 Knock-in Middle Age Rat Model in Repairing Renal Function Damage., PMID:39702946

Neprilysin-Mediated Amyloid Beta Clearance and Its Therapeutic Implications in Neurodegenerative Disorders., PMID:39698259

Neuroinflammation-targeted magnetic resonance imaging nanoprobes for the early diagnosis of Alzheimer's disease., PMID:39686760

Standardly Trained Peer Volunteer-Led, Social App Recruiting-Based Human Immunodeficiency Virus Testing Strategy Using Rapid Testing Kits (SPARK) Among Men Who Have Sex With Men: A Population-Based Survey Evaluation., PMID:39679350

Intranasal trivalent candidate vaccine induces strong mucosal and systemic immune responses against Neisseria gonorrhoeae., PMID:39660148

Improved glycemic and weight control with Dulaglutide addition in SGLT2 inhibitor treated obese type 2 diabetic patients at high cardiovascular risk in a real-world setting. The AWARE-2 study., PMID:39613122

Datasheet

Document Download

Anti-APP Antibody (R1J90).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-APP Antibody (R1J90) [RHC12515]
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