Catalog No.
RHC11305
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
HIST1H2AB, Histone H2A.2, Histone H2A type 1-B/E, Histone H2A/m, HIST1H2AE, H2AFA, Histone H2A/a, H2AC4, H2AFM
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04908
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1J81
Radiation-Induced Gamma-H2AX Foci Staining and Analysis., PMID:40418470
Detection of γ-H2A.X for Rapid Assessment of Genotoxic Agent-induced Double-strand DNA Breaks by Immunofluorescence., PMID:40257558
Human Source Severe Acute Respiratory Syndrome Coronavirus 2 Aerosol Transmission to Remote Sentinel Hamsters., PMID:40256039
Inhibition of EETosis with an anti-citrullinated histone antibody: a novel therapeutic approach for eosinophilic inflammatory disorders., PMID:40051617
ALKBH1 knockdown promotes the growth, migration and invasion of HTR-8/SVneo cells through regulating the m5C modification PSMD14., PMID:40025166
Real-Time, High-Throughput Microscopic Quantification of Human Neutrophil Extracellular Trap Release and Assessing the Pharmacology of Antagonists., PMID:39494869
On the Hunt for the Histone Code., PMID:39489218
Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch., PMID:39149911
Preclinical activity of datopotamab deruxtecan, a novel TROP2 directed antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (TROP2) in ovarian carcinoma., PMID:38981151
Multiplex imaging reveals spatially resolved DNA-damage response neighborhoods in TP53-mutated myelodysplastic neoplasms., PMID:38801208
FZD7-Targeted Nanoparticles to Enhance Doxorubicin Treatment of Triple-Negative Breast Cancer., PMID:38559981
B-cell intrinsic regulation of antibody mediated immunity by histone H2A deubiquitinase BAP1., PMID:38529289
O-GlcNAcylation stimulates the deubiquitination activity of USP16 and regulates cell cycle progression., PMID:38462164
Short Communication: Mosquito Histone 2A Protein Facilitate Japanese Encephalitis Virus Infection in the Mosquito., PMID:38441490
Anti-citrullinated histone monoclonal antibody CIT-013, a dual action therapeutic for neutrophil extracellular trap-associated autoimmune diseases., PMID:38031350
Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27., PMID:37756334
Pannexin 1 Modulates Angiogenic Activities of Human Endothelial Colony-Forming Cells Through IGF-1 Mechanism and Is a Marker of Senescence., PMID:37589139
Induction of NETosis in ovine colostral PMN upon exposure to Neospora caninum tachyzoites., PMID:37404777
EAE of Mice: Enzymatic Cross Site-Specific Hydrolysis of H2A Histone by IgGs against H2A, H1, H2B, H3, and H4 Histones and Myelin Basic Protein., PMID:37239982
EAE of Mice: Enzymatic Cross Site-Specific Hydrolysis of H2B Histone by IgGs against H1, H2A, H2B, H3, and H4 Histones and Myelin Basic Protein., PMID:37049736
Enzyme-Digested Edible Bird's Nest (EBND) Prevents UV and Arid Environment-Induced Cellular Oxidative Stress, Cell Death and DNA Damage in Human Skin Keratinocytes and Three-Dimensional Epithelium Equivalents., PMID:36978856
Failure of Costimulatory Blockade-induced Regulatory T Cells to Sustain Long-term Survival of High Ischemic Allografts., PMID:36978228
[Clinical significance and pathogenesis analysis of heterogeneous nuclear ribonucleoprotein U in acute myeloid leukemia]., PMID:36709168
Interplay Between the Histone Variant H2A.Z and the Epigenome in Pancreatic Cancer., PMID:36470770
Multiple Sclerosis: Enzymatic Cross Site-Specific Recognition and Hydrolysis of H3 Histone by IgGs against H3, H1, H2A, H2B, H4 Histones, Myelin Basic Protein, and DNA., PMID:36289924
Neospora caninum-induced NETosis in canine colostral polymorphonuclear neutrophils., PMID:36152379
Experimental Autoimmune Encephalomyelitis of Mice: Enzymatic Cross Site-Specific Hydrolysis of H4 Histone by IgGs against Histones and Myelin Basic Protein., PMID:36012448
Multiple Sclerosis: Enzymatic Cross Site-Specific Recognition and Hydrolysis of H2A Histone by IgGs against H2A, H1, H2B, H3 Histones, Myelin Basic Protein, and DNA., PMID:36009424
Intranasal and Intramuscular Immunization with Outer Membrane Vesicles from Serogroup C Meningococci Induced Functional Antibodies and Immunologic Memory., PMID:35950702
Autoimmune Diseases: Enzymatic cross Recognition and Hydrolysis of H2B Histone, Myelin Basic Protein, and DNA by IgGs against These Antigens., PMID:35897678
Characterization of the B-Cell Epitopes of Echinococcus granulosus Histones H4 and H2A Recognized by Sera From Patients With Liver Cysts., PMID:35770070
Romidepsin (FK228) improves the survival of allogeneic skin grafts through downregulating the production of donor-specific antibody via suppressing the IRE1α-XBP1 pathway., PMID:35557040
Evaluation of a new multi-epitope sequence of eight known Leishmania infantum antigens for HVL diagnosis by ELISA and Western blot., PMID:35381816
Antibody-suppressor CXCR5+ CD8+ T cellular therapy ameliorates antibody-mediated rejection following kidney transplant in CCR5 KO mice., PMID:35114045
Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis., PMID:35086525
Secretory immunoglobulin A from human milk hydrolyzes 5 histones and myelin basic protein., PMID:34802738
Extracellular vesicles from Fasciola gigantica induce cellular response to stress of host cells., PMID:34742714
The Major Peanut Allergen Ara h 2 Produced in Nicotiana benthamiana Contains Hydroxyprolines and Is a Viable Alternative to the E. Coli Product in Allergy Diagnosis., PMID:34671372
A Novel Blood-Brain Barrier-Permeable Chemotherapeutic Agent for the Treatment of Glioblastoma., PMID:34646647
Multiple Sclerosis: Enzymatic Cross Site-Specific Hydrolysis of H1 Histone by IgGs against H1, H2A, H2B, H3, H4 Histones, and Myelin Basic Protein., PMID:34439806
Sequential Chromatin Immunoprecipitation to Identify Heterotypic Nucleosomes., PMID:34382188
Phf5a regulates DNA repair in class switch recombination via p400 and histone H2A variant deposition., PMID:33938017
Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains., PMID:33810299
RNF8-ubiquitinated KMT5A is required for RNF168-induced H2A ubiquitination in response to DNA damage., PMID:33710666
Serum IgG2 antibody multicomposition in systemic lupus erythematosus and lupus nephritis (Part 1): cross-sectional analysis., PMID:33374003
Autoantibodies in outbred Swiss Webster mice following exposure to gold and mercury., PMID:33358697
Serum IgG2 antibody multi-composition in systemic lupus erythematosus and in lupus nephritis (Part 2): prospective study., PMID:33351137
Site-Specific Phosphorylation of Histone H1.4 Is Associated with Transcription Activation., PMID:33238524
Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms., PMID:33238161
Tumor Suppressive Maspin-Sensitized Prostate Cancer to Drug Treatment Through Negative Regulating Androgen Receptor Expression., PMID:33195208
For research use only. Not for human or drug use.
