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Anti-GBA Antibody (R1J43)

Catalog #:   RHC05701 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, WB
Accession: P04062
Overview

Catalog No.

RHC05701

Species reactivity

Human, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

SGTase, Cholesterol glucosyltransferase, GBA, Cholesteryl-beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, GLUC, Imiglucerase, Beta-glucocerebrosidase, Lysosomal acid GCase, Beta-GC, Alglucerase, GC, Lysosomal acid glucosylceramidase, Acid beta-glucosidase

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04062

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1J43

Data Image
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of GBA expression in U87-MG cell lysate.
References

Rituximab as First-Line Compared to Escalation Immunotherapy Is Associated With Lower Disability Accumulation in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Multicenter Cohort Study From Germany and the United Kingdom., PMID:40492480

CONFIDENCE treatment success: long-term real-world effectiveness and safety of ocrelizumab in Germany., PMID:40470489

Worse recovery from acute attacks and faster disability accumulation highlights the unmet need for improved treatment in patients with late-onset neuromyelitis optica spectrum disorders (COPTER-LO study)., PMID:40292288

Effects of Anti-CD20 Antibody Therapy on Immune Cell Dynamics in Relapsing-Remitting Multiple Sclerosis., PMID:40214505

[Blood vessels as a target organ: from Ormond's disease to immunoglobulin G4-related diseases]., PMID:40167754

Challenges in Gaucher disease: Perspectives from an expert panel., PMID:40112481

Capturing what matters: Patient-reported LGI1-ANTibody encephalitis outcome RatiNg scale (LANTERN)., PMID:39996410

Identification of Cell Receptors Responsible for Recognition and Binding of Lipid Nanoparticles., PMID:39993835

Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model., PMID:39984138

Early comorbidities and diagnostic challenges in people with multiple sclerosis with possible impact on disease management., PMID:39944057

Immunotherapy-Resistant Neuropathic Pain and Fatigue Predict Quality-of-Life in Contactin-Associated Protein-Like 2 Antibody Disease., PMID:39825737

C5 complement inhibition versus FcRn modulation in generalised myasthenia gravis., PMID:39798960

Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD., PMID:39730197

Abatacept Induces Long-Term Reconstitution of the B-Cell Niche in a Patient With CTLA-4 Haploinsufficiency: A Case Report., PMID:39689284

African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1., PMID:39668204

Reconciling predicted and measured viscosity parameters in high concentration therapeutic antibody solutions., PMID:39663541

Amygdala-predominant α-synuclein pathology is associated with exacerbated hippocampal neuron loss in Alzheimer's disease., PMID:39659977

A foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responses., PMID:39567664

Assessing the Manufacturability and Critical Quality Attribute Profiles of Anti-IL-8 Immunoglobulin G Mutant Variants., PMID:39509699

CSF and blood signatures support classification of limbic encephalitis subtypes., PMID:39401553

High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson's disease., PMID:39388267

Eculizumab Use in Neuromyelitis Optica Spectrum Disorders: Routine Clinical Care Data From a European Cohort., PMID:39353149

An Inducible Luminescent System to Explore Parkinson's Disease-Associated Genes., PMID:39273438

[Can SARS-CoV-2 Infection Status in Preschool Children be Predicted by Pandemic-related Attitudes and Concerns of their Parents? Data from the Würzburg Daycare Centre Studies (Wü-KiTa-CoV, 2020-2022)]., PMID:39137922

HLA and KIR genetic association and NK cells in anti-NMDAR encephalitis., PMID:39050850

Broader anti-EBV TCR repertoire in multiple sclerosis: disease specificity and treatment modulation., PMID:39021292

Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy., PMID:38773124

Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease., PMID:38712038

SARS-CoV-2 Seroprevalence in a Berlin Kindergarten Environment: A Cross-Sectional Study, September 2021., PMID:38671622

Efgartigimod and Ravulizumab for Treating Acetylcholine Receptor Auto-antibody-Positive (AChR-Ab+) Generalized Myasthenia Gravis: Indirect Treatment Comparison., PMID:38642198

Ravulizumab in myasthenic crisis: the first case report., PMID:38388927

[Should patients with ANCA-associated vasculitis undergoing maintenance therapy with rituximab receive cotrimoxazole prophylaxis?]., PMID:38272971

Depressive symptoms and anti-N-methyl-D-aspartate-receptor GluN1 antibody seropositivity in the PROSpective cohort with incident stroke., PMID:38033615

Multi-omics for COVID-19: driving development of therapeutics and vaccines., PMID:37936830

Negative hyperselection of elderly patients with RAS and BRAF wild-type metastatic colorectal cancer receiving initial panitumumab plus FOLFOX or 5-FU/LV., PMID:37924647

Effect of Echinacea purpurea (L.) Moench and its extracts on the immunization outcome of avian influenza vaccine in broilers., PMID:37839770

An Efficient and Scalable Method for the Production of Immunogenic SARS-CoV-2 Virus-like Particles (VLP) from a Mammalian Suspension Cell Line., PMID:37766145

Neither alpha-synuclein-preformed fibrils derived from patients with GBA1 mutations nor the host murine genotype significantly influence seeding efficacy in the mouse olfactory bulb., PMID:37662402

IGLV3-21R110 mutation has prognostic value in patients with treatment-naive chronic lymphocytic leukemia., PMID:37505099

Endo-radiofrequency subcision in the treatment of acne scars: a pilot investigative study., PMID:37400740

Osteonecrosis in Gaucher disease in the era of multiple therapies: Biomarker set for risk stratification from a tertiary referral center., PMID:37249220

Effect of Previous Disease-Modifying Therapy on Treatment Effectiveness for Patients Treated With Ocrelizumab., PMID:37041077

Autoimmune Encephalitis Misdiagnosis in Adults., PMID:36441519

SARS-CoV-2 neutralizing camelid heavy-chain-only antibodies as powerful tools for diagnostic and therapeutic applications., PMID:36189209

Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial., PMID:35946107

Molecular map of chronic lymphocytic leukemia and its impact on outcome., PMID:35927489

Highly Sensitive Love Mode Acoustic Wave Platform with SiO2 Wave-Guiding Layer and Gold Nanoparticles for Detection of Carcinoembryonic Antigens., PMID:35884339

Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study., PMID:35875815

Serum anti-NMDA-receptor antibodies and cognitive function after ischemic stroke (PROSCIS-B)., PMID:35718820

Label-free multiplex electrochemical immunosensor for early diagnosis of lysosomal storage disorders., PMID:35662258

Datasheet

Document Download

Anti-GBA Antibody (R1J43).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-GBA Antibody (R1J43) [RHC05701]
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