Catalog No.
RHB81301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Methyl-CpG-binding protein MBD3, Methyl-CpG-binding domain protein 3, MBD3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95983
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1G82
Melatonin-induced suppression of DNA methylation promotes odontogenic differentiation in human dental pulp cells., PMID:32718272
Thyroid hormone activates Xenopus MBD3 gene via an intronic TRE in vivo., PMID:31585895
β-Defensins Coordinate In Vivo to Inhibit Bacterial Infections of the Trachea., PMID:30154362
Human β-defensin-3 induces IL-8 release and apoptosis in airway smooth muscle cells., PMID:28437599
CRISPR/Cas9 Targets Chicken Embryonic Somatic Cells In Vitro and In Vivo and generates Phenotypic Abnormalities., PMID:27694906
AICAR sustains J1 mouse embryonic stem cell self-renewal and pluripotency by regulating transcription factor and epigenetic modulator expression., PMID:23988673
Toll-like receptor expression and activation in mice with experimental dry eye., PMID:23372055
The impact of ovarian stimulation on the expression of candidate reprogramming genes in mouse preimplantation embryos., PMID:23154201
Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14., PMID:20944649
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens., PMID:19733297
Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation., PMID:19536139
Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges., PMID:17671515
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression., PMID:14610093
MBD3 and HDAC1, two components of the NuRD complex, are localized at Aurora-A-positive centrosomes in M phase., PMID:12354758
Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3., PMID:12183469
Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma., PMID:11823513
Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation., PMID:11689684
MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase., PMID:10947852