Catalog No.
RHB53703
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Transmembrane GTPase MFN2, Mitofusin-2, KIAA0214, CPRP1, MFN2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95140
Applications
IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1G22
Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells., PMID:39906960
MEHP induced mitochondrial damage by promoting ROS production in CIK cells, leading to apoptosis, autophagy, cell cycle arrest., PMID:39586385
Zn0-Induced Cytotoxicity and Mitochondrial Stress in Microglia: Implications of the Protective Role of Immunoglobulin G In Vitro., PMID:39129512
Photobiomodulation therapy with light-emitting diode in stimulating adipose tissue mitochondria., PMID:37851070
Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells., PMID:37292700
Resveratrol Protects against Zearalenone-Induced Mitochondrial Defects during Porcine Oocyte Maturation via PINK1/Parkin-Mediated Mitophagy., PMID:36136579
Panax notoginseng saponin R1 attenuates allergic rhinitis through AMPK/Drp1 mediated mitochondrial fission., PMID:35623408
Amelioration of cancer cachexia with preemptive administration of tumor necrosis factor-α blocker., PMID:35400817
Transcriptomic and ultrastructural evidence indicate that anti-HMGB1 antibodies rescue organic dust-induced mitochondrial dysfunction., PMID:35244775
Mitofusin-2 regulates leukocyte adhesion and β2 integrin activation., PMID:34494308
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293
Intracellular AIBP (Apolipoprotein A-I Binding Protein) Regulates Oxidized LDL (Low-Density Lipoprotein)-Induced Mitophagy in Macrophages., PMID:33356389
Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses., PMID:32249716
Apolipoprotein E negatively regulates murine allergic airway inflammation via suppressing the activation of NLRP3 inflammasome and oxidative stress., PMID:32062073
Expression of mitochondrial dynamics markers during melanoma progression: Comparative study of head and neck cutaneous and mucosal melanomas., PMID:30916813
Emerging role of prodromal headache in patients with anti-N-methyl-D-aspartate receptor encephalitis., PMID:30787630
TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics., PMID:29715546
Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling., PMID:28943312
Advanced glycation end products influence mitochondrial fusion-fission dynamics through RAGE in human aortic endothelial cells., PMID:31966653
Cell-free mitochondrial fusion assay detected by specific protease reaction revealed Ca2+ as regulator of mitofusin-dependent mitochondrial fusion., PMID:28460043
Exogenous H2S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes., PMID:27998959
Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells., PMID:27364555
p38 MAP kinase-dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER-mitochondria association and mitochondria motility., PMID:26337390
Tumour necrosis factor-α promotes liver ischaemia-reperfusion injury through the PGC-1α/Mfn2 pathway., PMID:24898700
Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake., PMID:24085037
Leptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins., PMID:22961849
IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse., PMID:22769563
Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner., PMID:22484496
Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points., PMID:21856920
Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission., PMID:21701560
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage., PMID:21459773
Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts., PMID:20153825
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease., PMID:19605646
Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons., PMID:19445933
Effects of overexpression of huntingtin proteins on mitochondrial integrity., PMID:19039036
Identification of a novel mitochondrial complex containing mitofusin 2 and stomatin-like protein 2., PMID:17121834
Expression of HSG is essential for mouse blastocyst formation., PMID:16083859
Control of mitochondrial morphology by a human mitofusin., PMID:11181170
For research use only. Not for human or drug use.
