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Anti-KDM4B Antibody (R1G12)

Catalog #:   RHB49604 Specific References (7) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: O94953
Overview

Catalog No.

RHB49604

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000

Target

Jumonji domain-containing protein 2B, KDM4B, JmjC domain-containing histone demethylation protein 3B, JHDM3B, JMJD2B, Lysine-specific demethylase 4B, [histone H3]-trimethyl-L-lysine(9) demethylase 4B, KIAA0876

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O94953

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1G12

Data Image
  • Immunohistochemical
    Immunohistochemistry analysis of paraffin-embedded Human lung cancer using KDM4B/JMJD2B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot
    Western blot analysis of KDM4B in 293, COS7 lysates using KDM4B antibody.
References

Methylation of the JMJD2B epigenetic regulator differentially affects its ability to coactivate the ETV1 and JUN transcription factors., PMID:38213775

RETRACTED: KDM4A promotes the growth of non-small cell lung cancer by mediating the expression of Myc via DLX5 through the Wnt/β-catenin signaling pathway., PMID:33002480

Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy., PMID:27612013

The Prognostic Impact of Jumonji Domain-containing 2B in Patients with Resected Lung Adenocarcinoma., PMID:27630338

KDM4A, KDM4B and KDM4C in non-small cell lung cancer., PMID:26722485

Histone H3 lysine 4 monomethylation (H3K4me1) and H3 lysine 9 monomethylation (H3K9me1): distribution and their association in regulating gene expression under hyperglycaemic/hyperinsulinemic conditions in 3T3 cells., PMID:22951486

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein., PMID:15927959

Datasheet

Document Download

Anti-KDM4B Antibody (R1G12).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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For research use only. Not for human or drug use.

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Anti-KDM4B Antibody (R1G12) [RHB49604]
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