Catalog No.
RHB16901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Pituitary homeobox 3, Paired-like homeodomain transcription factor 3, Homeobox protein PITX3, PTX3, PITX3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O75364
Applications
FCM, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1F20
Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes., PMID:31248447
PITX3 mutations associated with autosomal dominant congenital cataract in the Chinese population., PMID:30816539
A novel frameshift mutation in CX46 associated with hereditary dominant cataracts in a Chinese family., PMID:28546921
Direct conversion of human fibroblasts into dopaminergic neural progenitor-like cells using TAT-mediated protein transduction of recombinant factors., PMID:25767075
Epigenetic regulation contributes to urocortin-enhanced midbrain dopaminergic neuron differentiation., PMID:25641682
Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons., PMID:22069189
Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons., PMID:18650325
Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures., PMID:18646205
Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra., PMID:18634852
The lens-regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression., PMID:18430088
Differential expression of the homeobox gene Pitx3 in midbrain dopaminergic neurons., PMID:16190884
PITX2 regulates procollagen lysyl hydroxylase (PLOD) gene expression: implications for the pathology of Rieger syndrome., PMID:11157981
Variation in residual PITX2 activity underlies the phenotypic spectrum of anterior segment developmental disorders., PMID:10958652
The Pitx2 protein in mouse development., PMID:10822271
N-Cadherin, a cell adhesion molecule involved in establishment of embryonic left-right asymmetry., PMID:10807574
The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals., PMID:9708733
For research use only. Not for human or drug use.
